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Quality in Sport

The Rising Role of Isometric Exercise in the Non-Pharmacological Management of Hypertension: A Review of Current Evidence and Clinical Guidelines
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The Rising Role of Isometric Exercise in the Non-Pharmacological Management of Hypertension: A Review of Current Evidence and Clinical Guidelines

Authors

  • Aleksandra Wielogórska District Medical Center in Grojec, ul. Ks. Piotra Skargi 10, 05-600 Grojec, Poland https://orcid.org/0009-0006-6582-6569
  • Maria Orłowska LUX MED Sp. z o.o. ul. Szturmowa 2, 02-678 Warszawa, Polska https://orcid.org/0009-0004-1009-2815
  • Maria Sanocka SZPITAL POWIATOWY GAJDA-MED SP https://orcid.org/0009-0000-9428-2464
  • Joanna Falana Independent Public Central Clinical Hospital in Warsaw, Banacha 1a, 02-097 Warsaw, Poland https://orcid.org/0009-0001-0110-9505
  • Agnieszka Kamińska Independent Public Health Care Facility in Garwolin https://orcid.org/0009-0002-3391-504X
  • Jana Kozłowska Independent Public Specialist Western Hospital of St. John Paul II, Daleka 11, 05-825 Grodzisk Mazowiecki, Poland https://orcid.org/0009-0008-5278-2864
  • Anna Kwiatkowska District Medical Center in Grojec ul. Ks. Piotra Skargi 10, 05-600 Grojec, Poland https://orcid.org/0009-0008-1334-6517
  • Agnieszka Przepióra Independent Public Complex of Health Care Facilities in Kozienice https://orcid.org/0009-0002-6368-537X
  • Karolina Trojnar Independent Public Health Care Facility in Garwolin, Garwolin, Poland https://orcid.org/0009-0003-5633-603X
  • Anna Żmigrodzka Independent Public Health Care Facility in Garwolin Lubelska 50, 08-400 Garwolin, Poland https://orcid.org/0009-0005-0179-8960
  • Klaudia Czernic-Goławska Independent Public Central Clinical Hospital in Warsaw https://orcid.org/0009-0009-7485-7246

DOI:

https://doi.org/10.12775/QS.2026.71.74822

Keywords

arterial hypertension, physical exercise, isometric training, aerobic training

Abstract

Background: Arterial hypertension is a major modifiable cardiovascular risk factor, which remains one of the most significant challenges of contemporary medicine. Despite the availability of effective pharmacotherapy, non-pharmacological interventions, such as physical activity, constitute an important element of hypertension management.

 

Aim: This paper aims to systematise the knowledge regarding the beneficial effects of physical activity on blood pressure control in hypertensive patients, taking into account physiological aspects, the type of physical exertion, and its dosage based on the latest guidelines.

 

Material and methods: A systematized review of the literature was conducted using PubMed and Google Scholar databases, covering the period from 2013 to 2026. The inclusion criteria focused on large-scale meta-analyses, systematic reviews, and current clinical guidelines (ESC 2024, ESH 2023, PTNT 2024) evaluating the hypotensive efficacy of various physical exertion modalities in adult populations.

 

Results: Physical exercise reduces blood pressure by enhancing endothelial function (increased NO bioavailability, decreased ET-1), reducing oxidative stress and modulating autonomic nervous system. While aerobic exercise is the standard recommendation, recent data highlight isometric resistance training as the most effective intervention for lowering blood pressure, both systolic blood pressure (SBP) and diastolic blood pressure (DBP).

 

Conclusions:

Physical activity overall is effective in lowering blood pressure, with the most pronounced effect in hypertensive patients. All exercise modalities - aerobic, isometric, resistance, combined training - help to maintain blood pressure control. Isometric exercise demonstrates the most favourable outcomes in hypertension management. A finding that should be taken into account when formulating recommendations for hypertensive patients in clinical practice.

References

1. Narodowy Fundusz Zdrowia [National Health Fund]. Raport o zdrowiu: Nadcisnienie tetnicze [Health report: Arterial hypertension]. Warsaw; 2019. Available from: https://ezdrowie.gov.pl/portal/home/badania-i-dane/zdrowe-dane/raporty/nfz-o-zdrowiu-nadcisnienie-tetnicze (Accessed: March 30, 2026).

2. World Health Organization. Global report on hypertension: the race against a silent killer. Geneva; 2023. Available from: https://www.who.int/publications/i/item/9789240081062 (Accessed: March 31, 2026).

3. Polish Society of Hypertension and Polish Cardiac Society Experts. 2024 Guidelines for the management of arterial hypertension in Poland — position statement of the Experts of the Polish Society of Hypertension/Polish Cardiac Society. Nadciśnienie Tętnicze w Praktyce. 2024;10(3-4):53–111. https://journals.viamedica.pl/nadcisnienie_tetnicze_w_praktyce/article/view/103769/81866

4. Mancia G, Kreutz R, Brunström M, et al. 2023 ESH Guidelines for the management of arterial hypertension. J Hypertens. 2023;41(12):1874-2071. https://doi.org/10.1097/HJH.0000000000003480

5. Edwards JJ, Deenmamode AHP, Griffiths M, et al. Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials. Br J Sports Med. 2023;57(20):1317-1326. https://doi.org/10.1136/bjsports-2022-106503

6. McEvoy JW, McCarthy CP, Bruno RM, et al. 2024 ESC Guidelines for the management of elevated blood pressure and hypertension. Eur Heart J. 2024;45(38):3912–4018. https://doi.org/10.1093/eurheartj/ehae178

7. Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018;39(33):3021–3104. https://doi.org/10.1093/eurheartj/ehy339

8. Thomopoulos C, et al. Do recent meta-analyses truly prove that treatment with blood pressure-lowering drugs is beneficial at any blood pressure value, no matter how low? A critical review. J Hypertens. 2022;40(5):839–846. https://doi.org/10.1097/HJH.0000000000003056

9. Liang C, Song Z, Yao X, Xiao Q, Fu H, Tang L. Exercise interventions for the effect of endothelial function in hypertensive patients: A systematic review and meta-analysis. J Clin Hypertens. 2024;26(6):599-614. https://doi.org/10.1111/jch.14818

10. Green DJ, Hopman MTE, Padilla J, et al. Vascular adaptation to exercise in humans: role of hemodynamic stimuli. Physiol Rev. 2017;97(2):495-528. https://doi.org/10.1152/physrev.00014.2016

11. Gao W, et al. Effects of different types of exercise on hypertension in middle-aged and older adults: a network meta-analysis. Front Public Health. 2023;11:1194124. https://doi.org/10.3389/fpubh.2023.1194124

12. Hao Z, et al. Aerobic, resistance, and isometric exercise to reduce blood pressure variability: a network meta-analysis of 15 clinical trials. J Clin Hypertens (Greenwich). 2025;27(5):e70050. https://doi.org/10.1111/jch.70050

13. Sun H, Zhang Y, Shi L. Advances in exercise-induced vascular adaptation: mechanisms, models, and methods. Front Bioeng Biotechnol. 2024;12:1370234. https://doi.org/10.3389/fbioe.2024.1370234

14. Farinatti P, et al. Editorial: post-exercise hypotension: clinical applications and potential mechanisms. Front Physiol. 2022;13:899497. https://doi.org/10.3389/fphys.2022.899497

15. Edwards JJ, Coleman DA, Ritti-Dias RM, et al. Isometric exercise training and arterial hypertension: an updated review. Sports Med. 2024;54:1459–1497. https://doi.org/10.1007/s40279-024-02036-x

16. Cornelissen VA, Smart NA. Exercise training for blood pressure: a systematic review and meta-analysis. J Am Heart Assoc. 2013;2(1):e004473. https://doi.org/10.1161/JAHA.112.004473

17. Pescatello LS, et al. Do the combined blood pressure effects of exercise and antihypertensive medications add up to the sum of their parts? A systematic meta-review. BMJ Open Sport Exerc Med. 2021;7(1):e000895 https://doi.org/10.1136/bmjsem-2020-000895

18. Smart NA, Way D, Carlson D, et al. Effects of isometric resistance training on resting blood pressure: individual participant data meta-analysis. J Hypertens. 2019;37(10):1927-1938. https://doi.org/10.1097/HJH.0000000000002105

19. Inder J, Carlson D, Dieberg G, et al. Isometric exercise training for blood pressure management: a systematic review and meta-analysis to optimize benefit. Hypertens Res. 2016;39:88–94. https://doi.org/10.1038/hr.2015.111

20. Coneglian JC, et al. Acute blood pressure response to different types of isometric exercise: a systematic review with meta-analysis. Rev Cardiovasc Med. 2023;24(2):60. https://doi.org/10.31083/j.rcm2402060

21. Pescatello LS, et al. Physical activity to prevent and treat hypertension: a systematic review. Med Sci Sports Exerc. 2019;51(6):1314-1323. https://doi.org/10.1249/MSS.0000000000001943

22. Fiega J, Lubaszka Z, Michalska M, Żurek U, Szewczyk D, Sikorska E. Influence of sport activity on hypertension - literature review. Journal of Education, Health and Sport. 2023;33(1):100-117. https://doi.org/10.12775/JEHS.2023.33.01.011

Quality in Sport

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Published

2026-09-13

How to Cite

1.
WIELOGÓRSKA, Aleksandra, ORŁOWSKA, Maria, SANOCKA, Maria, FALANA, Joanna, KAMIŃSKA, Agnieszka, KOZŁOWSKA, Jana, KWIATKOWSKA, Anna, PRZEPIÓRA, Agnieszka, TROJNAR, Karolina, ŻMIGRODZKA, Anna and CZERNIC-GOŁAWSKA, Klaudia. The Rising Role of Isometric Exercise in the Non-Pharmacological Management of Hypertension: A Review of Current Evidence and Clinical Guidelines. Quality in Sport. Online. 13 September 2026. Vol. 71, p. 74822. [Accessed 17 September 2026]. DOI 10.12775/QS.2026.71.74822.
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Vol. 71 (2026)

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Copyright (c) 2026 Aleksandra Wielogórska, Maria Orłowska, Maria Sanocka, Joanna Falana, Agnieszka Kamińska, Jana Kozłowska, Anna Kwiatkowska, Agnieszka Przepióra, Karolina Trojnar, Anna Żmigrodzka, Klaudia Czernic-Goławska

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