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Quality in Sport

Caffeine Sources and Exercise Performance: A Narrative Review of Anhydrous Caffeine, Coffee, and Energy Drinks
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Caffeine Sources and Exercise Performance: A Narrative Review of Anhydrous Caffeine, Coffee, and Energy Drinks

Authors

  • Izabela Czerny Independent Public Healthcare Institution of the Ministry of the Interior and Administration in Lublin, ul. Grenadierów 3, 20-331, Lublin, Poland https://orcid.org/0009-0005-6770-4314
  • Szymon Daniszewski Independent Public Healthcare Institution of the Ministry of the Interior and Administration in Lublin, ul. Grenadierów 3, 20-331, Lublin, Poland https://orcid.org/0009-0009-9481-1149
  • Wioleta Pluta Independent Public Health Care Facility in Puławy, Józefa Bema 1, 24-100 Puławy, Poland https://orcid.org/0009-0004-8990-7238
  • Roksana Milaniuk University Clinical Hospital No. 4 in Lublin, Doktora Kazimierza Jaczewskiego 8, 20-954 Lublin, Poland https://orcid.org/0009-0004-8199-4672
  • Aleksandra Drzewiecka University Clinical Hospital No. 4 in Lublin, Doktora Kazimierza Jaczewskiego 8, 20-954 Lublin, Poland https://orcid.org/0009-0004-7030-3266
  • Beata Surówka University Clinical Hospital No. 1 in Lublin, Stanisława Staszica 16, 20-081 Lublin, Poland https://orcid.org/0009-0008-0284-0077
  • Piotr Tylec Independent Public Health Care Facility in Puławy, Józefa Bema 1, 24-100 Puławy, Poland https://orcid.org/0009-0000-0490-2974
  • Krzysztof Talarowski Independent Public Health Care Centre in Puławy, Józefa Bema 1, 24-100 Puławy, Poland https://orcid.org/0009-0007-5651-6208
  • Arkadiusz Ściubak University Clinical Hospital No. 4 in Lublin, Doktora Kazimierza Jaczewskiego 8, 20-954 Lublin, Poland https://orcid.org/0009-0002-3292-1085
  • Aleksandra Pacek Medical University in Lublin, Aleje Racławickie 1, 20-059 Lublin, Poland https://orcid.org/0009-0009-4950-3577
  • Jakub Bryl Medical University in Lublin, Aleje Racławickie 1, 20-059 Lublin, Poland https://orcid.org/0009-0000-8772-2839

DOI:

https://doi.org/10.12775/QS.2026.70.74595

Keywords

caffeine supplementation, anhydrous caffeine, coffee, energy drinks, exercise performance, ergogenic aids

Abstract

Background: Caffeine is a widely used ergogenic aid available as anhydrous caffeine, coffee, and energy drinks. These sources differ in dosing accuracy, composition, and practical application, which may affect exercise performance.

Aim: This review aimed to compare the effects of anhydrous caffeine, coffee, and energy drinks on exercise performance and to assess whether ergogenic responses depend mainly on caffeine dose or also on source and product composition.

Material and methods: A narrative review supported by a structured search of PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar was conducted. Original studies, systematic reviews, meta-analyses, position stands, and relevant mechanistic publications were included, with emphasis on direct comparisons using equivalent or similar caffeine doses.

Results: Anhydrous caffeine provides the greatest dosing precision and the most standardized evidence. Coffee may produce comparable effects, particularly in endurance exercise, although caffeine content is more variable. Energy drinks may improve selected outcomes, but their multi-ingredient composition limits interpretation. Responses are also influenced by dose, timing, exercise type, habitual intake, genetic variability, individual sensitivity, and sleep-related effects.

Conclusions: Current evidence does not show clear superiority of one caffeine source. Similar doses may produce comparable effects in selected protocols, but more direct comparative studies are needed. Caffeine use should be individualized and tested during training.

References

1. Maughan, R. J., Burke, L. M., Dvorak, J., Larson-Meyer, D. E., Peeling, P., Phillips, S. M., Rawson, E. S., Walsh, N. P., Garthe, I., Geyer, H., Meeusen, R., van Loon, L. J. C., Shirreffs, S. M., Spriet, L. L., Stuart, M., Vernec, A., Currell, K., Ali, V. M., Budgett, R. G. M., Engebretsen, L. (2018). IOC consensus statement: Dietary supplements and the high-performance athlete. British Journal of Sports Medicine, 52(7), 439–455. https://doi.org/10.1136/bjsports-2018-099027

2. Grgic, J., Grgic, I., Pickering, C., Schoenfeld, B. J., Bishop, D. J., & Pedisic, Z. (2020). Wake up and smell the coffee: Caffeine supplementation and exercise performance—An umbrella review of 21 published meta-analyses. British Journal of Sports Medicine, 54(11), 681–688. https://doi.org/10.1136/bjsports-2018-100278

3. Guest, N. S., VanDusseldorp, T. A., Nelson, M. T., Grgic, J., Schoenfeld, B. J., Jenkins, N. D. M., Arent, S. M., Antonio, J., Stout, J. R., Trexler, E. T., Smith-Ryan, A. E., Goldstein, E. R., Kalman, D. S., & Campbell, B. I. (2021). International Society of Sports Nutrition position stand: Caffeine and exercise performance. Journal of the International Society of Sports Nutrition, 18(1), 1. https://doi.org/10.1186/s12970-020-00383-4

4. Jiménez, S. L., Díaz-Lara, J., Pareja-Galeano, H., & Del Coso, J. (2021). Caffeinated drinks and physical performance in sport: A systematic review. Nutrients, 13(9), 2944. https://doi.org/10.3390/nu13092944

5. Lowery, L. M., Anderson, D. E., Scanlon, K. F., Stack, A., Escalante, G., Campbell, S. C., Kerksick, C. M., Nelson, M. T., Ziegenfuss, T. N., VanDusseldorp, T. A., Kalman, D. S., Campbell, B. I., Kreider, R. B., & Antonio, J. (2023). International Society of Sports Nutrition position stand: Coffee and sports performance. Journal of the International Society of Sports Nutrition, 20(1), 2237952. https://doi.org/10.1080/15502783.2023.2237952

6. Hodgson, A. B., Randell, R. K., & Jeukendrup, A. E. (2013). The metabolic and performance effects of caffeine compared to coffee during endurance exercise. PLOS ONE, 8(4), e59561. https://doi.org/10.1371/journal.pone.0059561

7. Jagim, A. R., Harty, P. S., Tinsley, G. M., Kerksick, C. M., Gonzalez, A. M., Kreider, R. B., Arent, S. M., Jäger, R., Smith-Ryan, A. E., Stout, J. R., Campbell, B. I., VanDusseldorp, T. A., & Antonio, J. (2023). International Society of Sports Nutrition position stand: Energy drinks and energy shots. Journal of the International Society of Sports Nutrition, 20(1), 2171314. https://doi.org/10.1080/15502783.2023.2171314

8. Quinlivan, A., Irwin, C., Grant, G. D., Anoopkumar-Dukie, S., Skinner, T., Leveritt, M., & Desbrow, B. (2015). The effects of Red Bull energy drink compared with caffeine on cycling time-trial performance. International Journal of Sports Physiology and Performance, 10(7), 897–901. https://doi.org/10.1123/ijspp.2014-0481

9. Arnaud, M. J. (2011). Pharmacokinetics and metabolism of natural methylxanthines in animal and man. In B. B. Fredholm (Ed.), Methylxanthines: Handbook of Experimental Pharmacology (Vol. 200, pp. 33–91). Springer. https://doi.org/10.1007/978-3-642-13443-2_3

10. Grzegorzewski, J., Bartsch, F., Köller, A., & König, M. (2022). Pharmacokinetics of caffeine: A systematic analysis of reported data for application in metabolic phenotyping and liver function testing. Frontiers in Pharmacology, 12, 752826. https://doi.org/10.3389/fphar.2021.752826

11. Fredholm, B. B., Bättig, K., Holmén, J., Nehlig, A., & Zvartau, E. E. (1999). Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacological Reviews, 51(1), 83–133. https://doi.org/10.1016/S0031-6997(24)01396-6

12. Doherty, M., & Smith, P. M. (2005). Effects of caffeine ingestion on rating of perceived exertion during and after exercise: A meta-analysis. Scandinavian Journal of Medicine & Science in Sports, 15(2), 69–78. https://doi.org/10.1111/j.1600-0838.2005.00445.x

13. Graham, T. E. (2001). Caffeine and exercise: Metabolism, endurance and performance. Sports Medicine, 31(11), 785–807. https://doi.org/10.2165/00007256-200131110-00002

14. Nehlig, A. (2018). Interindividual differences in caffeine metabolism and factors driving caffeine consumption. Pharmacological Reviews, 70(2), 384–411. https://doi.org/10.1124/pr.117.014407

15. Southward, K., Rutherfurd-Markwick, K. J., & Ali, A. (2018). The effect of acute caffeine ingestion on endurance performance: A systematic review and meta-analysis. Sports Medicine, 48(8), 1913–1928. https://doi.org/10.1007/s40279-018-0939-8

16. Grgic, J., Trexler, E. T., Lazinica, B., & Pedisic, Z. (2018). Effects of caffeine intake on muscle strength and power: A systematic review and meta-analysis. Journal of the International Society of Sports Nutrition, 15, 11. https://doi.org/10.1186/s12970-018-0216-0

17. Salinero, J. J., Lara, B., & Del Coso, J. (2019). Effects of acute ingestion of caffeine on team sports performance: A systematic review and meta-analysis. Research in Sports Medicine, 27(2), 238–256. https://doi.org/10.1080/15438627.2018.1552146

18. Domaszewski, P. (2026). Coffee versus caffeine as ergogenic aids: Biological and methodological distinctions with implications for exercise performance and recovery. Nutrients, 18(2), 328. https://doi.org/10.3390/nu18020328

19. Trexler, E. T., Smith-Ryan, A. E., Roelofs, E. J., Hirsch, K. R., & Mock, M. G. (2016). Effects of coffee and caffeine anhydrous on strength and sprint performance. European Journal of Sport Science, 16(6), 702–710. https://doi.org/10.1080/17461391.2015.1085097

20. Richardson, D. L., & Clarke, N. D. (2016). Effect of coffee and caffeine ingestion on resistance exercise performance. Journal of Strength and Conditioning Research, 30(10), 2892–2900. https://doi.org/10.1519/JSC.0000000000001382

21. Clarke, N. D., Richardson, D. L., Thie, J., & Taylor, R. (2018). Coffee ingestion enhances one-mile running race performance. International Journal of Sports Physiology and Performance, 13(6), 789–794. https://doi.org/10.1123/ijspp.2017-0456

22. Lara, B., González-Millán, C., Salinero, J. J., Abián-Vicén, J., Areces, F., Barbero-Álvarez, J. C., Muñoz, V., Portillo, L. J., González-Ravé, J. M., & Del Coso, J. (2014). Caffeine-containing energy drink improves physical performance in female soccer players. Amino Acids, 46(5), 1385–1392. https://doi.org/10.1007/s00726-014-1709-z

23. Gwacham, N., & Wagner, D. R. (2012). Acute effects of a caffeine-taurine energy drink on repeated sprint performance of American college football players. International Journal of Sport Nutrition and Exercise Metabolism, 22(2), 109–116. https://doi.org/10.1123/ijsnem.22.2.109

24. Negaresh, R., Al-Riyami, S. A. A., Mardaniyan Ghahfarrokhi, M., Del Coso, J., Karimi, Z., Yaghoobi, M., & Bagheri, R. (2026). Caffeine use in sport: A systematic review and meta-analysis of acute side effects and implications for athlete health and safety. Sports Medicine. Advance online publication. https://doi.org/10.1007/s40279-026-02441-4

25. de Souza, J. G., Del Coso, J., Fonseca, F. de S., Silva, B. V. C., de Souza, D. B., Gianoni, R. L. da S., Filip-Stachnik, A., Serrão, J. C., & Claudino, J. G. (2022). Risk or benefit? Side effects of caffeine supplementation in sport: A systematic review. European Journal of Nutrition, 61(8), 3823–3834. https://doi.org/10.1007/s00394-022-02874-3

26. Pickering, C., & Kiely, J. (2018). Are the current guidelines on caffeine use in sport optimal for everyone? Inter-individual variation in caffeine ergogenicity, and a move towards personalised sports nutrition. Sports Medicine, 48(1), 7–16. https://doi.org/10.1007/s40279-017-0776-1

27 .Carvalho, A., Marticorena, F. M., Grecco, B. H., Barreto, G., & Saunders, B. (2022). Can I have my coffee and drink it? A systematic review and meta-analysis to determine whether habitual caffeine consumption affects the ergogenic effect of caffeine. Sports Medicine, 52(9), 2209–2220. https://doi.org/10.1007/s40279-022-01685-0

28. Clarke, N. D., & Richardson, D. L. (2021). Habitual caffeine consumption does not affect the ergogenicity of coffee ingestion during a 5-km cycling time trial. International Journal of Sport Nutrition and Exercise Metabolism, 31(1), 13–20. https://doi.org/10.1123/ijsnem.2020-0204

29. Southward, K., Rutherfurd-Markwick, K. J., Badenhorst, C. E., & Ali, A. (2018). The role of genetics in moderating the inter-individual differences in the ergogenicity of caffeine. Nutrients, 10(10), 1352. https://doi.org/10.3390/nu10101352

30. Barreto, G., Esteves, G. P., Marticorena, F., Oliveira, T. N., Grgic, J., & Saunders, B. (2024). Caffeine, CYP1A2 genotype, and exercise performance: A systematic review and meta-analysis. Medicine & Science in Sports & Exercise, 56(2), 328–339. https://doi.org/10.1249/MSS.0000000000003313

31. Mielgo-Ayuso, J., Marqués-Jiménez, D., Refoyo, I., Del Coso, J., León-Guereño, P., & Calleja-González, J. (2019). Effect of caffeine supplementation on sports performance based on differences between sexes: A systematic review. Nutrients, 11(10), 2313. https://doi.org/10.3390/nu11102313

32. Berjisian, E., Naderi, A., Mojtahedi, S., Grgic, J., Ghahramani, M. H., Karayigit, R., Forbes, J. L., Amaro-Gahete, F. J., & Forbes, S. C. (2022). Are caffeine’s effects on resistance exercise and jumping performance moderated by training status? Nutrients, 14(22), 4840. https://doi.org/10.3390/nu14224840

33. Bodur, M., Barkell, J., Li, X., & Sajadi Hezaveh, Z. (2025). Does caffeine supplementation affect sleep in athletes? A systematic review of nine randomized controlled trials. Clinical Nutrition ESPEN, 65, 76–85. https://doi.org/10.1016/j.clnesp.2024.11.007

Quality in Sport

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Published

2026-08-22

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CZERNY, Izabela, DANISZEWSKI, Szymon, PLUTA, Wioleta, MILANIUK, Roksana, DRZEWIECKA, Aleksandra, SURÓWKA, Beata, TYLEC, Piotr, TALAROWSKI, Krzysztof, ŚCIUBAK, Arkadiusz, PACEK, Aleksandra and BRYL, Jakub. Caffeine Sources and Exercise Performance: A Narrative Review of Anhydrous Caffeine, Coffee, and Energy Drinks. Quality in Sport. Online. 22 August 2026. Vol. 70, p. 74595. [Accessed 26 August 2026]. DOI 10.12775/QS.2026.70.74595.
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Copyright (c) 2026 Izabela Czerny, Szymon Daniszewski, Wioleta Pluta, Roksana Milaniuk, Aleksandra Drzewiecka, Beata Surówka, Piotr Tylec, Krzysztof Talarowski, Arkadiusz Ściubak, Aleksandra Pacek, Jakub Bryl

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