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Quality in Sport

Physical Activity as a Key Determinant of Health-Related Quality of Life: A Narrative Review
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  4. Medical Sciences

Physical Activity as a Key Determinant of Health-Related Quality of Life: A Narrative Review

Authors

  • Yana Lavrenchuk Norbert Barlicki Memorial Teaching Hospital No. 1, Medical University of Lodz, Łódź, Poland https://orcid.org/0009-0001-1510-2902
  • Natalia Drobińska https://orcid.org/0009-0006-9295-7564
  • Hanna Kasprzak https://orcid.org/0009-0000-9038-1035
  • Kacper Jaskulski https://orcid.org/0009-0006-1631-8058
  • Krzysztof Wichman https://orcid.org/0009-0006-8073-6211
  • Katarzyna Kowalenko https://orcid.org/0009-0003-5582-9713
  • Zuzanna Olszowiec https://orcid.org/0009-0003-6775-8086
  • Jan Szadkowski https://orcid.org/0009-0009-4276-8636

DOI:

https://doi.org/10.12775/QS.2026.69.74368

Keywords

physical activity, health-related quality of life, exercise, sedentary behaviour, public health, narrative review

Abstract

Background. Health-related quality of life (HRQoL) is an important indicator of physical, psychological and

social well-being. Regular physical activity is widely recognized as a modifiable factor supporting health

promotion, disease prevention and functional independence.

Aim. The aim of this narrative review was to summarize current evidence regarding the relationship between

physical activity and HRQoL across different population groups.

Materials and Methods. A narrative review was conducted using literature identified in PubMed, Scopus

and Web of Science. The review included international guidelines, systematic reviews, meta-analyses,

umbrella reviews and selected original studies published mainly between 2020 and 2025, with earlier

landmark publications included for context.

Results. The available evidence indicates that physical activity is consistently associated with better HRQoL

in children, adolescents, adults, older adults and individuals with chronic diseases. The most frequently

reported benefits include improved physical functioning, mental well-being, social participation and self-

rated health. Recent studies also emphasize the role of sedentary behaviour and 24-hour movement

behaviours.

Conclusions. Physical activity is an important determinant of HRQoL throughout the lifespan. Promoting

regular physical activity and reducing sedentary behaviour should remain key priorities in public health,

prevention and rehabilitation.

References

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Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020;54(24):1451-1462. https://doi.org/10.1136/bjsports-2020-102955

Warburton DER, Nicol CW, Bredin SSD. Health benefits of physical activity: the evidence. CMAJ. 2006;174(6):801-809. https://doi.org/10.1503/cmaj.051351

Gill DL, Hammond CC, Reifsteck EJ, Jehu CM, Williams RA, Adams MM, et al. Physical activity and quality of life. J Prev Med Public Health. 2013;46(Suppl 1):S28-S34. https://doi.org/10.3961/jpmph.2013.46.S.S28

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Schwartz BD, Liu H, MacDonald EE, Mekari S, O’Brien MW. Impact of physical activity and exercise training on health-related quality of life in older adults: an umbrella review. GeroScience. 2025;47:2879-2893. https://doi.org/10.1007/s11357-024-01493-6

Santos B, Monteiro D, Silva FM, Flores G, Bento T, Duarte-Mendes P. Objectively measured physical activity and sedentary behaviour on cardiovascular risk and health-related quality of life in adults: a systematic review. Healthcare (Basel). 2024;12(18):1866. https://doi.org/10.3390/healthcare12181866

Dale R, O’Rourke T, Nussbaumer-Streit B, Probst T. 24-hour movement behaviours and mental health in non-clinical populations: a systematic review. PLoS One. 2025;20(6):e0325445. https://doi.org/10.1371/journal.pone.0325445

Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major cause of chronic diseases. Compr Physiol. 2012;2(2):1143-1211. https://doi.org/10.1002/cphy.c110025

Janssen I, LeBlanc AG. Systematic review of the health benefits of physical activity and fitness in school-aged children and youth. Int J Behav Nutr Phys Act. 2010;7:40. https://doi.org/10.1186/1479-5868-7-40

Marker AM, Steele RG, Noser AE. Physical activity and health-related quality of life in children and adolescents: a systematic review and meta-analysis. Health Psychol. 2018;37(10):893-903. https://doi.org/10.1037/hea0000653

Wu XY, Han LH, Zhang JH, Luo S, Hu JW, Sun K. The influence of physical activity, sedentary behavior on health-related quality of life among the general population of children and adolescents: a systematic review. PLoS One. 2017;12(11):e0187668. https://doi.org/10.1371/journal.pone.0187668

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White RL, Vella SA, Biddle SJH, Sutcliffe J, Guagliano JM, Uddin R, et al. Physical activity and mental health: a systematic review and best-evidence synthesis of mediation and moderation studies. Int J Behav Nutr Phys Act. 2024;21:134. https://doi.org/10.1186/s12966-024-01676-6

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Barbosa BCR, de Menezes-Júnior LAA, Fróis LF, Vidigal MCA, de Paula W, Chagas CMS, et al. Replacing sedentary behavior with physical activity reduces symptoms of anxiety and depression: a study with young adults. BMC Public Health. 2025;25(1):2971. https://doi.org/10.1186/s12889-025-23523-4

Xu L, Ji Y, Wen X. Associations of physical activity and sedentary behavior with mental health among university students: the mediating role of cardiorespiratory fitness and moderating role of gender. BMC Public Health. 2025;25(1):3260. https://doi.org/10.1186/s12889-025-24528-9

Quality in Sport

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Published

2026-08-15

How to Cite

1.
LAVRENCHUK, Yana, DROBIŃSKA, Natalia, KASPRZAK, Hanna, JASKULSKI, Kacper, WICHMAN, Krzysztof, KOWALENKO, Katarzyna, OLSZOWIEC, Zuzanna and SZADKOWSKI, Jan. Physical Activity as a Key Determinant of Health-Related Quality of Life: A Narrative Review. Quality in Sport. Online. 15 August 2026. Vol. 69, p. 74368. [Accessed 17 September 2026]. DOI 10.12775/QS.2026.69.74368.
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Issue

Vol. 69 (2026)

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Medical Sciences

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Copyright (c) 2026 Yana Lavrenchuk, Natalia Drobińska, Hanna Kasprzak, Kacper Jaskulski, Krzysztof Wichman, Katarzyna Kowalenko, Zuzanna Olszowiec, Jan Szadkowski

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