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Quality in Sport

Exercise Prescription in Breast Cancer–Related Lymphedema: Safety, Functional Outcomes, and Practical Rehabilitation Strategies
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Exercise Prescription in Breast Cancer–Related Lymphedema: Safety, Functional Outcomes, and Practical Rehabilitation Strategies

Authors

  • Rema Mohaissen https://orcid.org/0009-0000-0289-1167
  • Mikołaj Tyla Medical University of Silesia in Katowice 15 Poniatowskiego Street, 40-055 Katowice, Poland https://orcid.org/0009-0009-4032-517X
  • Patryk Stabrawa Medical University of Silesia in Katowice 15 Poniatowskiego Street, 40-055 Katowice, Poland https://orcid.org/0009-0002-8918-6034
  • Laura Więcko Medical University of Silesia in Katowice 15 Poniatowskiego Street, 40-055 Katowice, Poland https://orcid.org/0009-0005-3749-6366
  • Katarzyna Trela Medical University of Silesia in Katowice 15 Poniatowskiego Street, 40-055 Katowice, Poland https://orcid.org/0009-0002-6631-5825
  • Aleksander Tuteja Medical University of Silesia in Katowice 15 Poniatowskiego Street, 40-055 Katowice, Poland https://orcid.org/0009-0006-5127-0889
  • Jakub Warecki Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice Plac Traugutta 2, 41-800 Zabrze, Poland https://orcid.org/0009-0007-5271-3810
  • Jakub Słota Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice Plac Traugutta 2, 41-800 Zabrze, Poland https://orcid.org/0009-0007-8790-6022
  • Kacper Solarz Leszek Giec Upper-Silesian Medical Centre of the Medical University of Silesia in Katowice, Ziołowa 45-47, 40-635 Katowice, Poland. https://orcid.org/0009-0000-7393-6529
  • Łukasz Dylewicz Szpital Murcki Sp. z o.o., Sokołowskiego 2, 40-749 Katowice, Poland https://orcid.org/0009-0007-4929-1063

DOI:

https://doi.org/10.12775/QS.2026.67.74232

Keywords

breast cancer-related lymphedema, exercise prescription, resistance training, rehabilitation, compression therapy, physical activity

Abstract

Breast cancer-related lymphedema (BCRL) is a chronic complication of breast cancer treatment that may affect limb volume, symptoms, upper-limb function, activity and quality of life. Although limb avoidance was historically recommended, current evidence supports structured exercise in rehabilitation and survivorship care. This narrative review synthesized evidence on exercise prescription in BCRL, focusing on safety, resistance training, functional outcomes, compression, assessment and practical strategies.The strongest evidence concerns progressive resistance training. In selected patients with stable BCRL, gradual resistance training does not appear to worsen lymphedema outcomes with monitoring and precautions. In at-risk populations, resistance or multimodal exercise does not appear to increase BCRL risk, although prevention evidence remains mixed. Aerobic and mixed exercise may support fitness, fatigue, function and quality of life, but BCRL-specific dosing is less defined. Compression use varies across studies, supporting individualized decisions. Assessment should combine limb measures, symptoms, function, stage and patient-reported outcomes.

Conclusions. Exercise should not be automatically contraindicated in patients with BCRL or women at risk. Prescription should consider baseline assessment, BCRL status, symptom stability, progressive loading, compression needs and monitoring. Future research should standardize definitions, compression protocols, exercise dosing, outcomes and event reporting.

References

1. Executive Committee of the International Society of Lymphology. The diagnosis and treatment of peripheral lymphedema: 2023 Consensus Document of the International Society of Lymphology. Lymphology. 2023;56(4):133-151. https://doi.org/10.2458/lymph.6372.

2. Davies C, Levenhagen K, Ryans K, Perdomo M, Gilchrist L. Interventions for breast cancer-related lymphedema: clinical practice guideline from the Academy of Oncologic Physical Therapy of APTA. Phys Ther. 2020;100(7):1163-1179. https://doi.org/10.1093/ptj/pzaa087.

3. Klassen AF, Tsangaris E, Kaur MN, Poulsen L, Beelen LM, Jacobsen AL, Jørgensen MG, Sørensen JA, Vasilic D, Dayan J, Mehrara B, Pusic AL. Development and psychometric validation of a patient-reported outcome measure for arm lymphedema: the LYMPH-Q Upper Extremity Module. Ann Surg Oncol. 2021;28(9):5166-5182. https://doi.org/10.1245/s10434-021-09887-y.

4. Ahmed RL, Thomas W, Yee D, Schmitz KH. Randomized controlled trial of weight training and lymphedema in breast cancer survivors. J Clin Oncol. 2006;24(18):2765-2772. https://doi.org/10.1200/JCO.2005.03.6749.

5. Schmitz KH, Ahmed RL, Troxel A, Cheville A, Smith R, Lewis-Grant L, Bryan CJ, Williams-Smith CT, Greene QP. Weight lifting in women with breast-cancer-related lymphedema. N Engl J Med. 2009;361(7):664-673. https://doi.org/10.1056/NEJMoa0810118.

6. Schmitz KH, Ahmed RL, Troxel AB, Cheville A, Lewis-Grant L, Smith R, Bryan CJ, Williams-Smith CT, Chittams J. Weight lifting for women at risk for breast cancer-related lymphedema: a randomized trial. JAMA. 2010;304(24):2699-2705. https://doi.org/10.1001/jama.2010.1837.

7. Cormie P, Pumpa K, Galvão DA, Turner E, Spry N, Saunders C, Zissiadis Y, Newton RU. Is it safe and efficacious for women with lymphedema secondary to breast cancer to lift heavy weights during exercise: a randomised controlled trial. J Cancer Surviv. 2013;7(3):413-424. https://doi.org/10.1007/s11764-013-0284-8.

8. Hasenoehrl T, Palma S, Ramazanova D, Kölbl H, Dorner TE, Keilani M, Crevenna R. Resistance exercise and breast cancer-related lymphedema-a systematic review update and meta-analysis. Support Care Cancer. 2020;28(8):3593-3603. https://doi.org/10.1007/s00520-020-05521-x.

9. Wang L, Shi YX, Wang TT, Chen KX, Shang SM. Breast cancer-related lymphoedema and resistance exercise: an evidence-based review of guidelines, consensus statements and systematic reviews. J Clin Nurs. 2023;32(9-10):2208-2227. https://doi.org/10.1111/jocn.16437.

10. Shah C, Whitworth P, Valente S, Schwarz GS, Kruse M, Kohli M, Brownson K, Lawson L, Dupree B, Vicini FA. Bioimpedance spectroscopy for breast cancer-related lymphedema assessment: clinical practice guidelines. Breast Cancer Res Treat. 2023;198(1):1-9. https://doi.org/10.1007/s10549-022-06850-7.

11. Shen A, Qiang W, Zhang L, Bian J, Zhu F, Zhang Z, Lu Q. Risk factors for breast cancer-related lymphedema: an umbrella review. Ann Surg Oncol. 2024;31(1):284-302. https://doi.org/10.1245/s10434-023-14277-7.

12. Kim DS, Sim YJ, Jeong HJ, Kim GC. Effect of active resistive exercise on breast cancer-related lymphedema: a randomized controlled trial. Arch Phys Med Rehabil. 2010;91(12):1844-1848. https://doi.org/10.1016/j.apmr.2010.09.008.

13. Basha MA, Aboelnour NH, Alsharidah AS, Kamel FH. Effect of exercise mode on physical function and quality of life in breast cancer-related lymphedema: a randomized trial. Support Care Cancer. 2022;30(3):2101-2110. https://doi.org/10.1007/s00520-021-06559-1.

14. Ammitzbøll G, Johansen C, Lanng C, Andersen EW, Kroman N, Zerahn B, Hyldegaard O, Wittenkamp MC, Dalton SO. Progressive resistance training to prevent arm lymphedema in the first year after breast cancer surgery: results of a randomized controlled trial. Cancer. 2019;125(10):1683-1692. https://doi.org/10.1002/cncr.31962.

15. Bloomquist K, Adamsen L, Hayes SC, Lillelund C, Andersen C, Christensen KB, Oturai P, Ejlertsen B, Tuxen MK, Møller T. Heavy-load resistance exercise during chemotherapy in physically inactive breast cancer survivors at risk for lymphedema: a randomized trial. Acta Oncol. 2019;58(12):1667-1675. https://doi.org/10.1080/0284186X.2019.1643916.

16. Cormie P, Singh B, Hayes S, Peake JM, Galvão DA, Taaffe DR, Spry N, Nosaka K, Cornish B, Schmitz KH, Newton RU. Acute inflammatory response to low-, moderate-, and high-load resistance exercise in women with breast cancer-related lymphedema. Integr Cancer Ther. 2016;15(3):308-317. https://doi.org/10.1177/1534735415617283.

17. Cormie P, Galvão DA, Spry N, Newton RU. Neither heavy nor light load resistance exercise acutely exacerbates lymphedema in breast cancer survivor. Integr Cancer Ther. 2013;12(5):423-432. https://doi.org/10.1177/1534735413477194.

18. Gülören G, Doğan Y, Özgül S, Gürşen C, Çinar GN, İpekten F, Akbayrak T. Acute effects of remedial exercises with and without compression on breast-cancer-related lymphedema. Healthcare (Basel). 2023;11(22):2949. https://doi.org/10.3390/healthcare11222949.

19. Omar MTA, Gwada RFM, Omar GSM, El-Sabagh RM, Mersal AEA. Low-intensity resistance training and compression garment in the management of breast cancer-related lymphedema: single-blinded randomized controlled trial. J Cancer Educ. 2020;35(6):1101-1110. https://doi.org/10.1007/s13187-019-01564-9.

20. Hayes SC, Singh B, Reul-Hirche H, Bloomquist K, Johansson K, Jönsson C, Plinsinga ML. The effect of exercise for the prevention and treatment of cancer-related lymphedema: a systematic review with meta-analysis. Med Sci Sports Exerc. 2022;54(8):1389-1399. https://doi.org/10.1249/MSS.0000000000002918.

21. Ramírez-Parada K, Sánchez C, Cantarero-Villanueva I, Reyes Á, Pinto MP, Bravo ML, Montt-Blanchard D, Acevedo F, Walbaum B, Alfaro-Barra M, Barra-Navarro M, Muñoz-Flores S, Pinto C, Muñiz S, Contreras-Briceño F, Merino T, Merino G. Randomized trial assessing prospective surveillance and exercise for preventing breast cancer-related lymphedema in high-risk patients. Arch Phys Med Rehabil. 2025;106(8):1163-1172. https://doi.org/10.1016/j.apmr.2025.03.002.

22. Campbell KL, Winters-Stone KM, Wiskemann J, May AM, Schwartz AL, Courneya KS, Zucker DS, Matthews CE, Ligibel JA, Gerber LH, Morris GS, Patel AV, Hue TF, Perna FM, Schmitz KH. Exercise guidelines for cancer survivors: consensus statement from International Multidisciplinary Roundtable. Med Sci Sports Exerc. 2019;51(11):2375-2390. https://doi.org/10.1249/MSS.0000000000002116.

23. Stout NL, Brown JC, Schwartz AL, Marshall TF, Campbell AM, Nekhlyudov L, Zucker DS, Basen-Engquist K, Campbell G, Meyerhardt J, Cheville AL, Covington KR, Ligibel JA, Sokolof J, Schmitz KH, Alfano CM. An exercise oncology clinical pathway: screening and referral for personalized interventions. Cancer. 2020;126(12):2750-2758. https://doi.org/10.1002/cncr.32860.

24. Covington KR, Marshall T, Campbell G, Williams GR, Fu JB, Kendig TD, Howe N, Alfano CM, Pergolotti M. Development of the Exercise in Cancer Evaluation and Decision Support (EXCEEDS) algorithm. Support Care Cancer. 2021;29(11):6469-6480. https://doi.org/10.1007/s00520-021-06208-7.

Quality in Sport

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Published

2026-08-07

How to Cite

1.
MOHAISSEN, Rema, TYLA, Mikołaj, STABRAWA, Patryk, WIĘCKO, Laura, TRELA, Katarzyna, TUTEJA, Aleksander, WARECKI, Jakub, SŁOTA, Jakub, SOLARZ, Kacper and DYLEWICZ, Łukasz. Exercise Prescription in Breast Cancer–Related Lymphedema: Safety, Functional Outcomes, and Practical Rehabilitation Strategies. Quality in Sport. Online. 7 August 2026. Vol. 67, p. 74232. [Accessed 9 August 2026]. DOI 10.12775/QS.2026.67.74232.
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Vol. 67 (2026)

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Copyright (c) 2026 Rema Mohaissen, Mikołaj Tyla, Patryk Stabrawa, Laura Więcko, Katarzyna Trela, Aleksander Tuteja, Jakub Warecki, Jakub Słota, Kacper Solarz, Łukasz Dylewicz

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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