From Hive to Health: Harnessing Propolis Accelerated Wound Recovery and Tissue Regeneration
DOI:
https://doi.org/10.12775/QS.2026.60.72757Keywords
Wound healing, Antimicrobial activity, Anti-inflammatory, Antioxidant, Polyphenols Flavonoids, Tissue regenerationAbstract
Wound management remains a critical challenge in modern medicine, particularly concerning chronic, infected, or slow-healing lesions. Propolis, a resinous mixture collected by honeybees from various plant sources, has emerged as a potent natural therapeutic agent due to its diverse biological properties. This narrative review synthesizes evidence from the most recent studies, investigating the efficacy of propolis in various wound healing and tissue regeneration contexts, ranging from oral mucositis to diabetic ulcers and surgical site infections. The findings consistently demonstrate that propolis promotes tissue regeneration, modulates inflammatory responses, and provides significant antimicrobial activity. Furthermore, the integration of propolis into advanced delivery systems, such as nanostructured lipid carriers and thermoresponsive gels, has been shown to enhance its therapeutic index compared to traditional formulations.
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Copyright (c) 2026 Filip Kręcina, Aleksander Karbowniczek, Kacper Gil, Justyna Daniek, Weronika Kaczmarek, Emilia Fitz, Mikołaj Brzeźniak, Krzysztof Drelich, Julia Mokracka, Alicja Grabarczyk
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