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Quality in Sport

Modern Treatment Approaches for Lymphedema: A Comprehensive Literature Review
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Modern Treatment Approaches for Lymphedema: A Comprehensive Literature Review

Authors

  • Anna Bulicz Medical University of Lodz, Al. Kościuszki 4. 90-419 Lodz. Poland https://orcid.org/0009-0008-7336-7096
  • Sebastian Kozłowski Medical University of Lodz, Al. Kościuszki 4. 90-419 Lodz. Poland https://orcid.org/0009-0000-1892-1869
  • Izabela Kmiecik Medical University of Lodz, Al. Kościuszki 4. 90-419 Lodz. Poland https://orcid.org/0009-0005-9905-3704
  • Monika Kukla https://orcid.org/0009-0006-1136-4194
  • Joanna Dziarnowska Medical University of Lodz, Al. Kościuszki 4. 90-419 Lodz. Poland https://orcid.org/0009-0001-7615-8408
  • Olga Kowalczyk Medical University of Lodz, Al. Kościuszki 4. 90-419 Lodz. Poland https://orcid.org/0009-0003-6908-7618
  • Marta Zdunek University Clinical Hospital No. 2, Medical University of Lodz, Żeromskiego 113, 90-549 Lodz, Poland https://orcid.org/0009-0006-4920-4460
  • Maciej Stodulski Municipal Hospital of St. John Paul II, ul. Jana Amosa Komeńskiego 35, 82-300 Elbląg, Poland https://orcid.org/0009-0001-1614-3511
  • Justyna Fiks Medical University of Lodz, Al. Kościuszki 4. 90-419 Lodz. Poland https://orcid.org/0009-0003-3833-7194
  • Izabela Kasprzycka Medical University of Lodz, Al. Kościuszki 4. 90-419 Lodz. Poland https://orcid.org/0009-0009-9416-4156

DOI:

https://doi.org/10.12775/QS.2026.58.72669

Keywords

lymphedema, rehabilitation, exercise therapy, lymphatic surgery, complete decongestive therapy

Abstract

Background:
Lymphedema is a chronic disorder caused by impaired lymphatic drainage, leading to tissue changes, reduced limb function, and limitations in physical performance. Although conservative and surgical treatments are established, their effects on exercise capacity and return to sport remain insufficiently summarized.

Objective:
This narrative review evaluated current and emerging lymphedema treatments, focusing on improving limb function, physical activity, and quality of life in active individuals.

Methods:
A narrative review of studies published between 2015 and 2026 was conducted, supported by key earlier literature. Databases were searched using terms related to lymphedema, rehabilitation, exercise therapy, surgery, and lymphatic reconstruction, with emphasis on functional outcomes.

Results:
Complete decongestive therapy remains the standard conservative treatment, effectively reducing limb volume and maintaining function. Compression therapy and structured exercise are central to symptom control. Progressive resistance and aerobic training are safe and may improve strength, endurance, and physical performance without worsening edema.

Surgical procedures such as lymphovenous anastomosis, vascularized lymph node transfer, and liposuction may provide additional benefits in selected patients. Emerging approaches, including immediate lymphatic reconstruction and regenerative therapies, may improve lymphatic function and prevent progression. Modern imaging techniques support earlier diagnosis and individualized rehabilitation.

Conclusions:
Current lymphedema management increasingly emphasizes functional rehabilitation and preservation of physical capacity rather than only limb volume reduction. Exercise appears safe and beneficial, while surgical and regenerative approaches may further improve outcomes. Evidence regarding athletes and return-to-sport outcomes remains limited, highlighting the need for sport-specific research.

References

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14. Kim HB, Jung SS, Cho MJ, et al. Comparative Analysis of Preoperative High Frequency Color Doppler Ultrasound versus MR Lymphangiography versus ICG Lymphography of Lymphatic Vessels in Lymphovenous Anastomosis. J Reconstr Microsurg. 2023;39(2):92-101. doi:10.1055/s-0042-1745745

15. Mihara M, Hara H, Araki J, et al. Indocyanine green (ICG) lymphography is superior to lymphoscintigraphy for diagnostic imaging of early lymphedema of the upper limbs. PLoS One. 2012;7(6):e38182. doi:10.1371/journal.pone.0038182

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18. Carl HM, Walia G, Bello R, et al. Systematic Review of the Surgical Treatment of Extremity Lymphedema. J Reconstr Microsurg. 2017;33(6):412-425. doi:10.1055/s-0037-1599100

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21. Brorson H. Liposuction gives complete reduction of chronic large arm lymphedema after breast cancer. Acta Oncol. 2000;39(3):407-420. doi:10.1080/028418600750013195

22. Brorson H, Svensson H. Liposuction combined with controlled compression therapy reduces arm lymphedema more effectively than controlled compression therapy alone. Plast Reconstr Surg. 1998;102(4):1058-1068.

23. Lafuente, H., Jaunarena, I., Ansuategui, E. et al. Cell therapy as a treatment of secondary lymphedema: a systematic review and meta-analysis. Stem Cell Res Ther 12, 578 (2021). https://doi.org/10.1186/s13287-021-02632-y

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Quality in Sport

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Published

2026-06-14

How to Cite

1.
BULICZ, Anna, KOZŁOWSKI, Sebastian, KMIECIK, Izabela, KUKLA, Monika, DZIARNOWSKA, Joanna, KOWALCZYK, Olga, ZDUNEK, Marta, STODULSKI, Maciej, FIKS, Justyna and KASPRZYCKA, Izabela. Modern Treatment Approaches for Lymphedema: A Comprehensive Literature Review. Quality in Sport. Online. 14 June 2026. Vol. 58, p. 72669. [Accessed 14 June 2026]. DOI 10.12775/QS.2026.58.72669.
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Vol. 58 (2026)

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Copyright (c) 2026 Anna Bulicz, Sebastian Kozłowski, Izabela Kmiecik, Monika Kukla, Joanna Dziarnowska, Olga Kowalczyk, Marta Zdunek, Maciej Stodulski, Justyna Fiks, Izabela Kasprzycka

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