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Quality in Sport

The Radiography and Ultrasonography in the Diagnosis and Monitoring of Necrotizing Enterocolitis in Neonates: A Focused Review
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The Radiography and Ultrasonography in the Diagnosis and Monitoring of Necrotizing Enterocolitis in Neonates: A Focused Review

Authors

  • Marta Majchrzycka Individual https://orcid.org/0009-0009-1359-1253
  • Natalia Czapla https://orcid.org/0009-0001-9029-5759
  • Martyna Graczyk https://orcid.org/0009-0000-3646-6441
  • Natalia Graczyk https://orcid.org/0009-0000-1140-6004
  • Piotr Ignyś https://orcid.org/0009-0009-5938-5412
  • Joanna Łopińska https://orcid.org/0009-0009-7554-8023
  • Mateusz Majchrzak https://orcid.org/0009-0008-4775-7525
  • Ewelina Strużyńska https://orcid.org/0009-0003-7749-0052
  • Wiktor Wisoky https://orcid.org/0009-0009-7226-9133
  • Weronika Ziółkowska https://orcid.org/0009-0003-1896-7877

DOI:

https://doi.org/10.12775/QS.2026.54.70427

Keywords

necrotizing enterocolitis, medical imaging, radiograph, ultrasound, advanced ultrasound techniques, artificial intelligence, pneumatosis intestinalis

Abstract

Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease that predominantly affects preterm neonates and remains a major source of morbidity and mortality in neonatal intensive care units (NICUs). An early diagnosis and timely surveillance is key to optimizing the outcome of the patients. Abdominal X ray (X Ray) remains the cornerstone of the imaging of NEC with pneumatosis intestinalis, portal venous gas and pneumoperitoneum being well defined radiological signs. With the increasing role of ultrasonography (USG) in the management of NEC, the bedside evaluation of bowel thickness, vascularity, motility and the assessment of fluid collections can sometimes detect signs of NEC before they become evident on radiography. This review summarizes the role of radiography and ultrasonography in the imaging of NEC, highlights their respective merits and shortcomings, and describes the practical approaches for their use in clinical practice. It also discusses the role of contrast enhanced ultrasound, near-infrared spectroscopy and artificial intelligence in the imaging of NEC.

References

[1] Lin, P. W., & Stoll, B. J. (2006). Necrotising enterocolitis. Lancet, 368(9543), 1271-1283. https://doi.org/10.1016/S0140-6736(06)69525-1

[2] Niño, D. F., Sodhi, C. P., & Hackam, D. J. (2016). Necrotizing enterocolitis: New insights into pathogenesis and mechanisms. Nature Reviews Gastroenterology & Hepatology, 13(10), 590-600. https://doi.org/10.1038/nrgastro.2016.119

[3] Tam, P. K. H., Chung, P. H. Y., St Peter, S. D., Gayer, C. P., Ford, H. R., Tam, G. C. H., Wong, K. K. Y., Pakarinen, M. P., & Davenport, M. (2017). Advances in paediatric gastroenterology. Lancet, 390(10099), 1072-1082. https://doi.org/10.1016/S0140-6736(17)32284-5

[4] Li, B., Yeganeh, M., Lee, D., Pierro, A., & Bhattacharjee, J. (2025). Exploring the complex pathophysiology of necrotizing enterocolitis in preterm neonates. Annual Review of Pathology. https://doi.org/10.1146/annurev-pathmechdis-070224-014223

[5] Juhl, S. M., Hansen, M. L., Gormsen, M., Skov, T., & Greisen, G. (2019). Staging of necrotising enterocolitis by Bell's criteria is supported by a statistical pattern analysis of clinical and radiological variables. Acta Paediatrica, 108(5), 842-848. https://doi.org/10.1111/apa.14469

[6] Neu, J., & Walker, W. A. (2011). Necrotizing enterocolitis. New England Journal of Medicine, 364(3), 255-264. https://doi.org/10.1056/NEJMra1005408

[7] Chen, S., Hu, Y., Liu, Q., Li, X., Wang, H., Wang, K., & Zhang, P. (2019). Application of abdominal sonography in diagnosis of infants with necrotizing enterocolitis. Medicine, 98(28), e16202. https://doi.org/10.1097/MD.0000000000016202

[8] Jia, L., Li, Z., Zhu, H., Wang, Y., & Chen, M. (2025). The diagnostic value of abdominal ultrasound in the progression of necrotizing enterocolitis in low-birth-weight neonates. Medicine, 104(43), e45427. https://doi.org/10.1097/MD.0000000000045427

[9] Deeg, K. H. (2019). Sonographic and Doppler sonographic diagnosis of necrotizing enterocolitis in preterm infants and newborns. Ultraschall in der Medizin, 40(3), 292-318. https://doi.org/10.1055/a-0879-8110

[10] Cuna, A. C., Reddy, N., Robinson, A. L., & Chan, S. S. (2018). Bowel ultrasound for predicting surgical management of necrotizing enterocolitis: A systematic review and meta-analysis. Pediatric Radiology, 48(5), 658-666. https://doi.org/10.1007/s00247-017-4056-x

[11] Le Cacheux, C., Daneman, A., Pierro, A., Bhombal, S., & Defined, A. (2023). Association of new sonographic features with outcome in neonates with necrotizing enterocolitis. Pediatric Radiology, 53(9), 1894-1902. https://doi.org/10.1007/s00247-023-05641-6

[12] Al-Hamad, S., Hackam, D. J., Goldstein, S. D., Grissom, L., & Bhombal, S. (2018). Contrast-enhanced ultrasound and near-infrared spectroscopy of the neonatal bowel: Novel, bedside, noninvasive, and radiation-free imaging for early detection of necrotizing enterocolitis. American Journal of Perinatology, 35(14), 1358-1365. https://doi.org/10.1055/s-0038-1655768

[13] Gokli, A., Acord, M. R., Hwang, M., Defined, A., & Defined, B. (2020). Contrast-enhanced US in pediatric patients: Overview of bowel applications. Radiographics, 40(6), 1743-1762. https://doi.org/10.1148/rg.2020200019

[14] Hwang, M., Tierradentro-García, L. O., Dennis, R. A., & Anupindi, S. A. (2022). The role of ultrasound in necrotizing enterocolitis. Pediatric Radiology, 52(4), 702-715. https://doi.org/10.1007/s00247-021-05187-5

[15] Patel, A. K., Lazar, D. A., Burrin, D. G., Smith, E. O., Gleghorn, J. P., & Premkumar, M. H. (2014). Abdominal near-infrared spectroscopy measurements are lower in preterm infants at risk for necrotizing enterocolitis. Pediatric Critical Care Medicine, 15(8), 735-741. https://doi.org/10.1097/PCC.0000000000000211

[16] van der Heide, M., Hulscher, J. B. F., Bos, A. F., & Kooi, E. M. W. (2021). Near-infrared spectroscopy as a diagnostic tool for necrotizing enterocolitis in preterm infants. Pediatric Research, 90(1), 148-155. https://doi.org/10.1038/s41390-020-01186-8

[17] Zamora, I. J., Stoll, B., Ethun, C. G., Sheikh, F., Yu, L., Burrin, D. G., & Olutoye, O. O. (2015). Low abdominal NIRS values and elevated plasma intestinal fatty acid-binding protein in a premature piglet model of necrotizing enterocolitis. PLoS One, 10(6), e0125437. https://doi.org/10.1371/journal.pone.0125437

[18] Schat, T. E., Schurink, M., van der Laan, M. E., Hulscher, J. B. F., Bos, A. F., & Kooi, E. M. W. (2016). Near-infrared spectroscopy to predict the course of necrotizing enterocolitis. PLoS One, 11(5), e0154710. https://doi.org/10.1371/journal.pone.0154710

[19] Dodd, A. C., Lehane, A. J., Lee, A., Hintz, S. R., & Sylvester, K. G. (2026). First-in-human pilot study of broadband optical spectroscopy (BOS) as noninvasive surveillance for necrotizing enterocolitis (NEC). Journal of Pediatric Surgery, 162978. https://doi.org/10.1016/j.jpedsurg.2026.162978

[20] Wu, Y., Yang, H., Luo, X., Chen, L., & Zhang, W. (2026). Deep learning feature-based model on abdominal radiography outperforms experts for early necrotizing enterocolitis diagnosis in neonates. European Radiology. https://doi.org/10.1007/s00330-025-12264-y

[21] Yung, K. W., Sivaraj, J., De Coppi, P., Eaton, S., & Giuliani, S. (2024). Diagnosing necrotizing enterocolitis via fine-grained visual classification. IEEE Transactions on Biomedical Engineering, 71(11), 3160-3169. https://doi.org/10.1109/TBME.2024.3409642

[22] Weller, J. H., Scheese, D., Tragesser, C., Sodhi, C. P., & Hackam, D. J. (2024). Artificial intelligence vs. doctors: Diagnosing necrotizing enterocolitis on abdominal radiographs. Journal of Pediatric Surgery, 59(10), 161592. https://doi.org/10.1016/j.jpedsurg.2024.06.001

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Published

2026-04-10

How to Cite

1.
MAJCHRZYCKA, Marta, CZAPLA, Natalia, GRACZYK , Martyna, GRACZYK , Natalia, IGNYŚ, Piotr, ŁOPIŃSKA, Joanna, MAJCHRZAK, Mateusz, STRUŻYŃSKA, Ewelina, WISOKY, Wiktor and ZIÓŁKOWSKA, Weronika. The Radiography and Ultrasonography in the Diagnosis and Monitoring of Necrotizing Enterocolitis in Neonates: A Focused Review. Quality in Sport. Online. 10 April 2026. Vol. 54, p. 70427. [Accessed 11 April 2026]. DOI 10.12775/QS.2026.54.70427.
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Vol. 54 (2026)

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Copyright (c) 2026 Marta Majchrzycka, Natalia Czapla, Martyna Graczyk , Natalia Graczyk , Piotr Ignyś, Joanna Łopińska, Mateusz Majchrzak, Ewelina Strużyńska, Wiktor Wisoky, Weronika Ziółkowska

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