Recurrent Electrical Storm in a Patient with Chronic Heart Disease: A Case Report
DOI:
https://doi.org/10.12775/QS.2025.46.66675Keywords
electrical storm, ventricular tachycardia, ischemic cardiomyopathy, CRT-D, stellate ganglion block, ablation, flecainide, depression, anxietyAbstract
Background: Electrical storm (ES) is a life‑threatening cardiac emergency characterized by recurrent, sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) episodes that are often refractory to standard therapies. It predominantly affects patients with structural heart disease - most notably those with ischemic cardiomyopathy and chronic heart failure with reduced ejection fraction (HFrEF).
Case Presentation: We describe a 75‑year‑old man with ischemic cardiomyopathy and HFrEF admitted for sustained VT unresponsive to conventional management. His history included multiple catheter ablations, prior myocardial infarction, and an implanted ICD placed for recurrent ventricular arrhythmias. Despite additional ablations and antiarrhythmic medication, he continued to experience electrical storms. Definitive rhythm control was achieved via a multidisciplinary strategy comprising left stellate ganglion block, upgrade to cardiac resynchronization therapy‑defibrillator (CRT‑D), personalized ICD reprogramming, and initiation of flecainide in combination with propranolol. Device interrogation at follow‑up confirmed effective biventricular pacing and complete suppression of sustained ventricular arrhythmias.
Conclusion: This case underscores the complexity of managing ES in patients with advanced structural heart disease and multiple comorbidities. Individualized device programming, innovative pharmacological regimens, and targeted interventional techniques can stabilize patients refractory to standard approaches. A holistic, team‑based model of care is essential to optimize outcomes and improve quality of life in this high‑risk population.
References
1. Priori SG, Blomström-Lundqvist C, Mazzanti A, et al. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2015;36(41):2793–867.
2. Conti S, Pala S, Biagioli V, Del Giorno G, Zucchetti M, Russo E, Marino V, Dello Russo A, Casella M, Pizzamiglio F, Catto V, Tondo C, Carbucicchio C. Electrical storm: A clinical and electrophysiological overview. World J Cardiol. 2015 Sep 26;7(9):555-61. doi: 10.4330/wjc.v7.i9.555. PMID: 26413232; PMCID: PMC4577682.
3. Elsokkari I, Sapp JL. Electrical storm: Prognosis and management. Prog Cardiovasc Dis. 2021 May-Jun;66:70-79. doi: 10.1016/j.pcad.2021.06.007. PMID: 34332662.
4. Gatzoulis KA, Andrikopoulos GK, Apostolopoulos T. Electrical storm: current clinical evidence and therapeutic strategies. Ann Noninvasive Electrocardiol. 2020;25(6):e12779.
5. Nanthakumar K, Epstein AE, Kay GN, Plumb VJ, Lee DS. Ventricular tachycardia storm: a consequence of changing paradigms in sudden cardiac death prevention. J Am Coll Cardiol. 2004;43(10):1713–9.
6. Sesselberg HW, Moss AJ, McNitt S, et al. Ventricular arrhythmia storm in postinfarction patients with implantable defibrillators. J Am Coll Cardiol. 2007;50(6):556–61.
7. León V, Medina-Ravell VA, Di Biase L, et al. Pathophysiology and clinical management of electrical storm in the modern era. Indian Pacing Electrophysiol J. 2020;20(1):1–11.
8. Jentzer, J, Noseworthy, P, Kashou, A. et al. Multidisciplinary Critical Care Management of Electrical Storm: JACC State-of-the-Art Review. JACC. 2023 Jun, 81 (22) 2189–2206.
9. Arya A, Bode F. Catheter ablation for electrical storm: when, how and for whom? Curr Opin Cardiol. 2014;29(1):36–41.
10. Ajijola OA, Vaseghi M, Mahajan A, Shivkumar K. Catheter ablation of ventricular tachycardia storm. Curr Cardiol Rep. 2012;14(5):519–27.
11.. Bradfield JS, Ajijola OA, Vaseghi M, Shivkumar K. Mechanisms and management of refractory ventricular arrhythmias in the age of autonomic modulation. Heart Rhythm. 2018 Aug;15(8):1252-1260. doi: 10.1016/j.hrthm.2018.02.015. Epub 2018 Feb 14. PMID: 29454137.
12. Sangpornsuk N, Rungpradubvong V, Tiensantisuk T, Leelapattana P, Chokesuwattanakul R, Prechawat S. Flecainide use in arrhythmic patients who have structural heart disease. Ther Adv Drug Saf. 2025 Feb 12;16:20420986251316462. doi: 10.1177/20420986251316462. PMID: 39944374; PMCID: PMC11815794.
13. Ghezzi ES, Sharman RLS, Selvanayagam JB, Psaltis PJ, Sanders P, Astley JM, Knayfati S, Batra V, Keage HAD. Burden of mood symptoms and disorders in implantable cardioverter defibrillator patients: a systematic review and meta-analysis of 39 954 patients. Europace. 2023 Jun 2;25(6):euad130. doi: 10.1093/europace/euad130. PMID: 37311667; PMCID: PMC10264222.
14. Pedersen SS, van Domburg RT, Theuns DA, Jordaens L, Erdman RA. Concerns about the implantable cardioverter defibrillator: a determinant of anxiety and depressive symptoms independent of experienced shocks. Am Heart J. 2005 Apr;149(4):664-9. doi: 10.1016/j.ahj.2004.06.031. PMID: 15990750.
15. Sears SF Jr, Conti JB. Quality of life and psychological functioning of ICD patients. Heart. 2002;87(5):488–493. doi:10.1136/heart.87.5.488
16. Irvine J, Firestone J, Ong L, et al. A randomized controlled trial of cognitive behavior therapy tailored to psychological adaptation to an implantable cardioverter defibrillator. Psychosom Med. 2011;73(3):226–233. doi:10.1097/PSY.0b013e31820afc63
17. Irvine J, Firestone J, Ong L, et al. A randomized controlled trial of cognitive behavior therapy tailored to psychological adaptation to an implantable cardioverter defibrillator. Psychosom Med. 2011;73(3):226–233. doi:10.1097/PSY.0b013e31820afc63.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Wojciech Grabski, Paulina Strzałkowska, Maciej Hobot, Dominika Szaj, Michalina Raczkowska, Aleksandra Trojańska

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Stats
Number of views and downloads: 58
Number of citations: 0