Physical Activity, Diet and Overweight in Hashimoto’s Thyroiditis: A Current Literature Review
DOI:
https://doi.org/10.12775/QS.2025.47.66615Keywords
Hashimoto's thyroiditis, Nutrition, Physical activity, Healthy lifestyleAbstract
Introduction and purpose. Hashimoto's disease affects approximately 3% of the population and its prevalence is steadily increasing. As a result, unverified information and lifestyle-related advice are increasingly appearing on social media. This research aims to systematize knowledge on excessive body weight, physical activity, and nutrition in Hashimoto’s disease.
Material and methods. Scientific articles on Hashimoto’s disease were searched in medical databases such as PubMed, Google Scholar, and Embase, focusing on information about the disease, excessive body weight and healthy lifestyle.
State of knowledge. In Hashimoto’s disease, excessive body weight is more commonly seen even in the euthyroid phase. Adhering to the doctors’ treatment recommendations remains the key strategy. Social media should not replace evidence-based information about healthy living with this condition. Balanced nutrition and physical activity are important in combating obesity in Hashimoto’s disease. So far, no specific types of diets or exercise have been shown to offer superior outcomes in patients with this condition. Taking care of patients’ mental health is a crucial element in supporting obesity treatment in the disease, while weight reduction combined with physical activity may lead to an alleviation of depressive symptoms.
Conclusions. The most important strategy, alongside pharmacological treatment supervised by a specialist, is adopting a health-promoting lifestyle based on recommendations for the general population. However, individual patient differences must be considered, and lifestyle modifications should be guided holistically under physician supervision.
References
1. Ralli M, Angeletti D, Fiore M, D’Aguanno V, Lambiase A, Artico M, et al. Hashimoto’s thyroiditis: An update on pathogenic mechanisms, diagnostic protocols, therapeutic strategies, and potential malignant transformation. Autoimmunity Reviews 2020 Oct;19(10):102649.
2. Paknys G, Kondrotas A, Kėvelaitis E. Risk factors and pathogenesis of Hashimoto’s thyroiditis. Medicina. 2009 Jul 12;45(7):574.
3. Hiromatsu Y, Satoh H, Amino N. Hashimoto’s Thyroiditis: History and Future Outlook. Hormones. 2013 Jan;12(1):12–8.
4. Dayan CM, Daniels GH. Chronic Autoimmune Thyroiditis. New England Journal of Medicine. 1996 Jul 11;335(2):99–107.
5. Ragusa F, Fallahi P, Elia G, Gonnella D, Paparo SR, Giusti C, et al. Hashimotos’ thyroiditis: Epidemiology, pathogenesis, clinic and therapy. Best Practice & Research Clinical Endocrinology & Metabolism. 2019 Nov;33(6):101367
6. Petra Petranović Ovčariček, Rainer Görges, Luca Giovanella. Autoimmune Thyroid Diseases. Seminars in Nuclear Medicine. 2023 Dec 1;54(2).
7. Ajjan RA, Weetman AP. The Pathogenesis of Hashimoto’s Thyroiditis: Further Developments in our Understanding. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2015;47(10):702–10.
8. Weetman AP. An update on the pathogenesis of Hashimoto’s thyroiditis. Journal of Endocrinological Investigation. 2020 Dec 17;44(5).
9. Tokhirovna EG. Modern Methods in the Diagnosis of Autoimmune Thyroiditis. AJBCI. 2024 Oct. 17 [cited 2025 Jun. 2];1(10):43-50.
10. McGrogan A, Seaman HE, Wright JW, de Vries CS. The incidence of autoimmune thyroid disease: a systematic review of the literature. Clinical Endocrinology. 2008 Nov;69(5):687–96.
11. Hu X, Chen Y, Shen Y, Tian R, Sheng Y, Que H. Global prevalence and epidemiological trends of Hashimoto’s thyroiditis in adults: A systematic review and meta-analysis. Frontiers in Public Health. 2022 Oct 13;10.
12. Chu A, Liu S, Chen Y, Xia Z. The efficacy of Chinese patent medicine Xiaojin capsule in the treatment of Hashimoto’s thyroiditis: A systematic review and meta-analysis. European Journal of Integrative Medicine. 2024 Sep;70:102395.
13. Caturegli P, De Remigis A, Rose NR. Hashimoto thyroiditis: Clinical and diagnostic criteria. Autoimmunity Reviews. 2014 Apr;13(4-5):391–7.
14. Patel N, Aruna Anantharaj, Roopa Kodimyala, Adik Umeshkumar Patel, Rane M, Anju Maria Thomas, et al. Analyzing Instagram Posts on Hypothyroidism: Characteristics, Information Types, Quality, and Reliability. Curēus. 2023 Oct 16
15. Barrios L, Walgama E, Chen Y, Sacks WL, Ho AS. Emerging social media trends in thyroid and parathyroid surgery. Annals of Thyroid. 2020 Jun;5:5–5.
16. Kadłubek S, Mąka M, Kalinowski S, Woźniak J, Kapturska N, Cymerys K, et al. Impact of Apple Cider Vinegar on Insulin Resistance and Related Conditions: Benefits, Mechanisms, and Potential Risks - Literature Review. Journal of Education, Health and Sport. 2024 Dec 8;76:56408.
17. Pyzik A, Grywalska E, Matyjaszek-Matuszek B, Roliński J. Immune Disorders in Hashimoto’s Thyroiditis: What Do We Know So Far? Journal of Immunology Research. 2015;2015:1–8.
18. Wrońska K, Hałasa M, Szczuko M. The Role of the Immune System in the Course of Hashimoto’s Thyroiditis: The Current State of Knowledge. International Journal of Molecular Sciences. 2024 Jan 1;25(13):6883
19. Bogusławska J, Godlewska M, Gajda E, Piekiełko-Witkowska A. Cellular and molecular basis of thyroid autoimmunity. European Thyroid Journal. 2022 Feb 1;11(1).
20. Klubo-Gwiezdzinska J, Wartofsky L. Hashimoto thyroiditis: An evidence-based guide: Etiology, diagnosis and treatment. Polish Archives of Internal Medicine. 2022 Mar 3;132(3).
21. Shahbaz A, Aziz K, Umair M, Sachmechi I. Prolonged Duration of Hashitoxicosis in a Patient with Hashimoto’s Thyroiditis: A Case Report and Review of Literature. Cureus. 2018 Jun 14;10(6).
22. Groenewegen KL, Mooij CF, van Trotsenburg ASP. Persisting symptoms in patients with Hashimoto’s disease despite normal thyroid hormone levels: Does thyroid autoimmunity play a role? A systematic review. Journal of Translational Autoimmunity. 2021;4:100101.
23. Huang Q, Pan K, Zhang Y, Li S, Li J. Effects of calorie-restricted diet on health state and intestinal flora in Hashimoto’s thyroiditis patients: Study protocol for a randomized controlled trial. PubMed. 2024 Sep 1;33(3):397–404.
24. S L, G R. Thyroid Function and Obesity. Journal of Clinical Research in Pediatric Endocrinology 2012 Nov 15;4(4).
25. Mikulska AA, Karaźniewicz-Łada M, Filipowicz D, Ruchała M, Główka FK. Metabolic Characteristics of Hashimoto’s Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management—An Overview. International Journal of Molecular Sciences. 2022 Jan 1;23(12):6580
26. Baranowska-Bik A, Bik W. The Association of Obesity with Autoimmune Thyroiditis and Thyroid Function-Possible Mechanisms of Bilateral Interaction. Falhammar H, editor. International Journal of Endocrinology. 2020 Dec 14;2020:1–14.
27. Song R, Wang B, Yao Q, Li Q, Jia X, Zhang J. The Impact of Obesity on Thyroid Autoimmunity and Dysfunction: A Systematic Review and Meta-Analysis. Frontiers in Immunology. 2019 Oct 1;10.
28. Poplawska-Kita A, Telejko B, Katarzyna Siewko, Kosciuszko-Zdrodowska M, Wawrusewicz-Kurylonek N, Kretowski A, et al. Body mass analysis in patients with Hashimoto thyroiditis. Endocrine Abstracts. 2014 Apr 17;
29. Ciccone MM, De Pergola G, Porcelli MT, Scicchitano P, Caldarola P, Iacoviello M, et al. Increased carotid IMT in overweight and obese women affected by Hashimoto’s thyroiditis: an adiposity and autoimmune linkage? BMC Cardiovascular Disorders. 2010 May 28;10(1).
30. Mousa U. Fat Distribution and Metabolic Profile in Subjects with Hashimoto’s Thyroiditis. Acta Endocrinologica. 2018;14(1):105–12.
31. Gacek M, Wojtowicz A, Jolanta Kędzior. Physical Activity, Nutritional Behaviours and Depressive Symptoms in Women with Hashimoto’s Disease. Healthcare. 2025 Mar 13;13(6):620–0.
32. Ríos-Prego M, Anibarro L, Sánchez-Sobrino P. Relationship between thyroid dysfunction and body weight: a not so evident paradigm. International Journal of General Medicine. 2019 Aug;Volume 12:299–304.
33. Fu X, Wang Y, Zhao F, Cui R, Xie W, Liu Q, et al. Shared biological mechanisms of depression and obesity: focus on adipokines and lipokines. Shared biological mechanisms of depression and obesity: focus on adipokines and lipokines. 2023 Jun 29;15(12).
34. Wang B, Huang J, Chen L. Association Between Depression and Anxiety Disorders with Euthyroid Hashimoto’s Thyroiditis: A Systematic Review and Meta-analysis. Comprehensive Psychoneuroendocrinology. 2024 Dec 1;100279–9.
35. Wojciech Cyna, Aleksandra Wojciechowska, Weronika Szybiak-Skora, Katarzyna Lacka. The Impact of Environmental Factors on the Development of Autoimmune Thyroiditis—Review. Biomedicines. 2024 Aug 7;12(8):1788–8.
36. Ihnatowicz P, Jerzy Gębski, Małgorzata Drywień. Effects of Autoimmune Protocol (AIP) diet on changes in thyroid parameters in Hashimoto’s disease. 2023 Jun 1;
37. Matana A, Torlak V, Brdar D, Popović M, Lozić B, Barbalić M, et al. Dietary Factors Associated with Plasma Thyroid Peroxidase and Thyroglobulin Antibodies. Nutrients. 2017 Oct 28;9(11):1186.
38. Ruggeri RM, Giovinazzo S, Barbalace MC, Cristani M, Alibrandi A, Vicchio TM, et al. Influence of Dietary Habits on Oxidative Stress Markers in Hashimoto’s Thyroiditis. Thyroid. 2021 Jan 1;31(1):96–105.
39. World Health Organization. Healthy Diet World Health Organization. 2020.
40. Lankhaar JAC, Kemler E, Hofstetter H, Collard DCM, Zelissen PMJ, Stubbe JH, et al. Physical activity, sports participation and exercise-related constraints in adult women with primary hypothyroidism treated with thyroid hormone replacement therapy. Journal of Sports Sciences. 2021 Jun 24;39(21):1–10.
41. American Thyroid Association. Hashimoto’s Thyroiditis. American Thyroid Association. 2025.
42. ETA Guidelines - eurothyroid.com. Eurothyroid.com. 2018.
43. Marko Vuletić, Kaličanin D, Žižić AB, Maja Cvek, Sladić S, Veselin Škrabić, et al. Occupational Physical Activity and Regular Exercise Are Inversely Correlated with Thyroid Function in Patients with Hashimoto’s Thyroiditis. Diseases, 2024 Nov 6; 12(11):281–1.
44. Kamińska W, Wiśniewska K, Okręglicka K, Pazura I, Nitsch-Osuch A. Lifestyle intervention towards Mediterranean Diet, physical activity adherence and anthropometric parameters in normal weight women with Polycystic Ovary Syndrome or Hashimoto’s Thyroiditis – preliminary study. Annals of Agricultural and Environmental Medicine. 2023 Feb 15;
45. World Health Organization. WHO guidelines on physical activity and sedentary behaviour. 2020.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Szymon Kalinowski, Sabina Kadłubek, Julia Woźniak, Natalia Kapturska, Jakub Kamiński, Dominik Sikora, Kinga Cymerys, Piotr Kardaszewski, Ewa Góralczyk, Magdalena Mąka

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Stats
Number of views and downloads: 46
Number of citations: 0