The Efficacy and safety of honey as a treatment for pediatric cough and relation to future sport performance: a literature review
DOI:
https://doi.org/10.12775/QS.2025.44.62837Keywords
cough, Upper Respiratory Tract Infections, Honey, Honey and sportsAbstract
Honey has been used for centuries as a natural aid in treating various ailments, including respiratory tract infections. Its antibacterial, antiviral, anti-inflammatory, and immunomodulatory properties make it an interesting subject of research in the context of relieving the symptoms of upper respiratory tract infections, especially cough.
Cough is one of the most common symptoms in children. Although it is usually self-limiting and does not require causal treatment, it can significantly affect the child's comfort and worry parents. Cough, especially dry and paroxysmal, often worsens at night, disturbing the sleep of both the child and caregivers, which in turn can prolong the convalescence process and lead to a deterioration in general well-being.
Modern scientific research increasingly confirms the effectiveness of natural bee products as support in treating upper respiratory tract infections. Honey affects many levels: it can soothe a sore throat, reduce cough, improve the functioning of the immune system, and shorten the duration of symptoms. The variety of available honey species, rich in bioactive compounds such as flavonoids, phenolic acids, and enzymes, creates a wide range of possibilities for their therapeutic use. This article aims to review the literature on the effect of honey on the relief of symptoms of upper respiratory tract infections. The mechanisms of honey action, its chemical composition, clinical evidence, and possible limitations in its use will be analysed.
References
[1] Murgia V, Manti S, Licari A, De Filippo M, Ciprandi G, Marseglia GL. Upper Respiratory Tract Infection-Associated Acute Cough and the Urge to Cough: New Insights for Clinical Practice. Pediatr Allergy Immunol Pulmonol. 2020 Mar;33(1):3-11. doi: 10.1089/ped.2019.1135. PMID: 33406022; PMCID: PMC7875114.
[2] Simona Terzo, Flavia Mulè, Antonella Amato, Honey and obesity-related dysfunctions: a summary on health benefits,The Journal of Nutritional Biochemistry, Volume 82,2020,108401,ISSN 0955-2863,
[3] Palma-Morales M, Huertas JR, Rodríguez-Pérez C. A Comprehensive Review of the Effect of Honey on Human Health. Nutrients. 2023 Jul 6;15(13):3056. doi: 10.3390/nu15133056. PMID: 37447382; PMCID: PMC10346535.
[4] Vîjan LE, Mazilu IC, Enache C, Enache S, Topală CM. Botanical Origin Influence on Some Honey Physicochemical Characteristics and Antioxidant Properties. Foods. 2023 May 25;12(11):2134. doi: 10.3390/foods12112134. PMID: 37297382; PMCID: PMC10253141.
[5] Foti Randazzese S, Toscano F, Gambadauro A, La Rocca M, Altavilla G, Carlino M, Caminiti L, Ruggeri P, Manti S. Neuromodulators in Acute and Chronic Cough in Children: An Update from the Literature. Int J Mol Sci. 2024 Oct 18;25(20):11229. doi: 10.3390/ijms252011229. PMID: 39457010; PMCID: PMC11508565.
[6] Marseglia G.L., Manti S., Chiappini E., Brambilla I., Caffarelli C., Calvani M., Cardinale F., Cravidi C., Duse M., Martelli A., et al. Acute cough in children and adolescents: A systematic review and a practical algorithm by the Italian Society of Pediatric Allergy and Immunology. Allergol. Immunopathol. 2021;49:155–169. doi: 10.15586/aei.v49i2.45.
[7] Weinberger M, Hurvitz M. Diagnosis and management of chronic cough: similarities and differences between children and adults. F1000Res. 2020 Jul 22;9:F1000 Faculty Rev-757. doi: 10.12688/f1000research.25468.1. PMID: 32765833; PMCID: PMC7385707.
[8] Bergmann M, Haasenritter J, Beidatsch D, Schwarm S, Hörner K, Bösner S, et al. Coughing children in family practice and primary care: a systematic review of prevalence, aetiology and prognosis. BMC Pediatr. 2021;21(1):260. doi: 10.1186/s12887-021-02739-4.
[9] Bergmann M, Haasenritter J, Beidatsch D, Schwarm S, Hörner K, Bösner S, et al. Prevalence, aetiologies and prognosis of the symptom cough in primary care: a systematic review and meta-analysis. BMC Fam Pract. 2021;22(1):151. doi: 10.1186/s12875-021-01501-0
[10] Bergmann M, Haasenritter J, Beidatsch D, Schwarm S, Hörner K, Bösner S, Grevenrath P, Schmidt L, Viniol A, Donner-Banzhoff N, Becker A. Coughing children in family practice and primary care: a systematic review of prevalence, aetiology and prognosis. BMC Pediatr. 2021 Jun 4;21(1):260. doi: 10.1186/s12887-021-02739-4. PMID: 34088294; PMCID: PMC8176681.
[11] Palmu S, Heikkilä P, Kivistö JE, Poutanen R, Korppi M, Renko M et al (2022) Cough medicine prescriptions for children were significantly reduced by a systematic intervention that reinforced national recommendations. Acta Paediatr Oslo Nor 1992 111(6):1248–9
[12] Kuitunen I, Renko M. Honey for acute cough in children - a systematic review. Eur J Pediatr. 2023 Sep;182(9):3949-3956. doi: 10.1007/s00431-023-05066-1. Epub 2023 Jun 25. PMID: 37355498; PMCID: PMC10570220.
[13] Marseglia GL, Manti S, Chiappini E, Brambilla I, Caffarelli C, Calvani M, Cardinale F, Cravidi C, Duse M, Martelli A, Minasi D, Del Giudice MM, Pajno G, Peroni DG, Tosca MA, Licari A, Ciprandi G. Acute cough in children and adolescents: A systematic review and a practical algorithm by the Italian Society of Pediatric Allergy and Immunology. Allergol Immunopathol (Madr). 2021 Mar 1;49(2):155-169. doi: 10.15586/aei.v49i2.45. PMID: 33641306.
[14] Abuelgasim H, Albury C, Lee J. Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis. BMJ Evid Based Med. 2021 Apr;26(2):57-64. doi: 10.1136/bmjebm-2020-111336. Epub 2020 Aug 18. PMID: 32817011.
[15] Benoît Mbiya-Mukinayi et al. Managing of acute pediatric cough in Africa: prescription of cough suppressants and associated complications. PAMJ Clinical Medicine. 2024;14:19. [doi: 10.11604/pamj-cm.2024.14.19.41440]
[16] Vanker A, Gie RP, Zar HJ. The association between environmental tobacco smoke exposure and childhood respiratory disease: a review. Expert Rev Respir Med. 2017 Aug;11(8):661-673. doi: 10.1080/17476348.2017.1338949. Epub 2017 Jun 14. PMID: 28580865; PMCID: PMC6176766.
[17] Mashat GD, Hazique M, Khan KI, Ramesh P, Kanagalingam S, Ul Haq Z, Victory Srinivasan N, Khan AI, Khan S. Comparing the Effectiveness of Honey Consumption With Anti-Cough Medication in Pediatric Patients: A Systematic Review. Cureus. 2022 Sep 20;14(9):e29346. doi: 10.7759/cureus.29346. PMID: 36284810; PMCID: PMC9583571.
[18] Anibasa FO, Abuba T, Dankyau M. Effect of Honey on Cough Symptoms in Children with Upper Respiratory Tract Infection: A Randomised Controlled Trial. West Afr J Med. 2022 Sep 16;39(9):928-934. PMID: 36126325.
[19] Abuelgasim H, Albury C, Lee J. Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis. BMJ Evid Based Med. 2021 Apr;26(2):57-64. doi: 10.1136/bmjebm-2020-111336. Epub 2020 Aug 18. PMID: 32817011.
[20] Mashat GD, Hazique M, Khan KI, Ramesh P, Kanagalingam S, Ul Haq Z, Victory Srinivasan N, Khan AI, Khan S. Comparing the Effectiveness of Honey Consumption With Anti-Cough Medication in Pediatric Patients: A Systematic Review. Cureus. 2022 Sep 20;14(9):e29346. doi: 10.7759/cureus.29346. PMID: 36284810; PMCID: PMC9583571.
[21] Jan Suđi, Kristian Pastor, Marko Ilić, Predrag Radišić, Nikola Martić & Nemanja Petrović. (2024) A novel approach for improved honey identification and scientific definition: a case of buckwheat honey. Journal of Apicultural Research 63:5, pages 977-987.
[22] Nguyen HTL, Panyoyai N, Paramita VD, Mantri N, Kasapis S. Physicochemical and viscoelastic properties of honey from medicinal plants. Food Chem. 2018 Feb 15;241:143-149. doi: 10.1016/j.foodchem.2017.08.070. Epub 2017 Aug 24. PMID: 28958512.
[23] Goldberg B, Danino D, Levinsky Y, Levy I, Straussberg R, Dabaja-Younis H, Guri A, Almagor Y, Tasher D, Elad D, Baider Z, Blum S, Scheuerman O. Infant Botulism, Israel, 2007-2021. Emerg Infect Dis. 2023 Feb;29(2):235-241. doi: 10.3201/eid2902.220991. PMID: 36692296; PMCID: PMC9881770.
[24] Antonucci L, Locci C, Schettini L, Clemente MG, Antonucci R. Infant botulism: an underestimated threat. Infect Dis (Lond). 2021 Sep;53(9):647-660. doi: 10.1080/23744235.2021.1919753. Epub 2021 May 8. PMID: 33966588.
[25] Garispe A, Cherry S. Infant Botulism. J Educ Teach Emerg Med. 2023 Jul 31;8(3):O33-O60. doi: 10.21980/J88350. PMID: 37575412; PMCID: PMC10414984.
[26] Di Costanzo M, De Paulis N, Peveri S, Montagni M, Berni Canani R, Biasucci G. Anaphylaxis caused by artisanal honey in a child: a case report. J Med Case Rep. 2021 May 14;15(1):235. doi: 10.1186/s13256-021-02823-4. PMID: 33985563; PMCID: PMC8120922.
[27] Sadeghi F, Akhlaghi M, Salehi S. Adverse effects of honey on low-density lipoprotein cholesterol and adiponectin concentrations in patients with type 2 diabetes: a randomized controlled cross-over trial. J Diabetes Metab Disord. 2020 Apr 14;19(1):373-380. doi: 10.1007/s40200-020-00518-z. PMID: 32550188; PMCID: PMC7271300.
[28] Cheever VJ, Mohajeri A, Patel K, Burris RC, Hung M. Impact of Free Sugar Consumption on Dental Caries: A Cross-Sectional Analysis of Children in the United States. Dent J (Basel). 2025 Jan 22;13(2):48. doi: 10.3390/dj13020048. PMID: 39996922; PMCID: PMC11854531.
[29] Demel K, Talaska J, Dziedzic M, Król J, Szatkowska Z, Odrzywolska O, Niemczyk W, Zawilska A. Use of honey in dentistry - literature review. Wiad Lek. 2025;78(1):156-161. doi: 10.36740/WLek/199734. PMID: 40023868.
[30] Grabek-Lejko D, Hyrchel T. The Antibacterial Properties of Polish Honey against Streptococcus mutans-A Causative Agent of Dental Caries. Antibiotics (Basel). 2023 Nov 19;12(11):1640. doi: 10.3390/antibiotics12111640. PMID: 37998842; PMCID: PMC10669562.
[31] Hills SP, Mitchell P, Wells C, Russell M. Honey Supplementation and Exercise: A Systematic Review. Nutrients. 2019 Jul 12;11(7):1586. doi: 10.3390/nu11071586. PMID: 31336992; PMCID: PMC6683082.
[32] Hemmati H, Alkasasbeh WJ, Hemmatinafar M, Salesi M, Pirmohammadi S, Imanian B, Rezaei R. Effect of a honey-sweetened beverage on muscle soreness and recovery of performance after exercise-induced muscle damage in strength-trained females. Front Physiol. 2024 Sep 17;15:1426872. doi: 10.3389/fphys.2024.1426872. Erratum in: Front Physiol. 2024 Dec 04;15:1523903. doi: 10.3389/fphys.2024.1523903. PMID: 39355153; PMCID: PMC11442837.
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Copyright (c) 2025 Joanna Maria Szewczyk, Aleksandra Małgorzata Rybak, Donat Sławomir Cupiał, Natalia Katarzyna Seliga, Katarzyna Płudowska, Kamila Ptasińska, Paulina Grzeszczyk, Anna Rosińska, Karolina Arciszewska, Katarzyna Krawczyk, Harold Jakubowski

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