The impact of gut microbiota, inflammation and oxidative stress on endometriosis, pain, quality of life and condition of patients’ health
DOI:
https://doi.org/10.12775/QS.2025.43.61444Keywords
Endometriosis, Inflammation, Oxidative Stress, Microbiome, Gut microbiome, Microbiota, Gut Microbiota, chronic pelvic painAbstract
Endometriosis is a chronic complex, systemic inflammatory disease which affects
5-10% of reproductive-age women. There is a need for a surgical laparoscopy to establish the
correct diagnosis, which means that the disease is still underdiagnosed and leads to
undertreated patients’ health condition. Scientists are trying to find other factors causing and
exacerbating this disease. Some of them like gut microbiome, inflammation and oxidative
stress associated with endometriosis are recent discoveries.
References
1. Hugh S Taylor, Alexander M Kotlyar, Valerie A Flores; https://
pubmed.ncbi.nlm.nih.gov/33640070/; DOI: 10.1016/S0140-6736(21)00389-5
2. C a t h e r i n e A l l a i r e , M o h a m e d A B e d a i w y, P a u l J Yo n g ; h t t p s : / /
pubmed.ncbi.nlm.nih.gov/36918177/; DOI: 10.1503/cmaj.220637
3. Gabriela Cano-Herrera, Sylvia Salmun Nehmad, Jimena Ruiz de Chávez Gascón,
Amairani Méndez Vionet, Ximena A van Tienhoven, María Fernanda Osorio Martínez,
Mauricio Muleiro Alvarez, Mariana Ximena Vasco Rivero, María Fernanda López
Torres, María Jimena Barroso Valverde, Isabel Noemi Torres, Alexa Cruz Olascoaga,
Maria Fernanda Bautista Gonzalez, José Antonio Sarkis Nehme, Ignacio Vélez
Rodrígun, Eder Gabriel Rivera Rosas, Dante Carbajal Ocampo, Ramiro Cabrera
Carranco; https://pubmed.ncbi.nlm.nih.gov/39062050/; DOI: 10.3390/
biomedicines12071476
4. Jim Manos; https://pubmed.ncbi.nlm.nih.gov/35393656/; DOI: 10.1111/apm.13225
5. Hanne Van Gestel, Celine Bafort, Christel Meuleman, Carla Tomassetti, Arne Vanhie;
https://pubmed.ncbi.nlm.nih.gov/38943813/; DOI: 10.1016/j.rbmo.2024.103848
6. M a r i a A r i a d n a O c h o a B e r n a l , A s g e r a l l y T F a z l e a b a s ; h t t p s : / /
pubmed.ncbi.nlm.nih.gov/38892003/; DOI: 10.3390/ijms25115815
7. Philippe R Koninckx, Rodrigo Fernandes, Anastasia Ussia, Larissa Schindler, Arnaud
Wattiez, Shaima Al-Suwaidi, Bedayah Amro, Basma Al-Maamari, Zeinab Hakim,
Muna Tahlak; https://pubmed.ncbi.nlm.nih.gov/34899597/; DOI: 10.3389/
fendo.2021.745548
8. Teresa Mira Gruber, Sylvia Mechsner; https://pubmed.ncbi.nlm.nih.gov/34205040/;
DOI: 10.3390/cells10061381
9. K Matsuura, H Ohtake, H Katabuchi, H Okamura; https://pubmed.ncbi.nlm.nih.gov/
10087424/; DOI: 10.1159/000052855
10. J e l i z a v e t a L a m c e v a , R o m a n s U l j a n o v s , I l z e S t r u m f a ; h t t p s : / /
pubmed.ncbi.nlm.nih.gov/36901685/; DOI: 10.3390/ijms24054254
11. Teresa Mira Gruber, Sylvia Mechsner; https://pubmed.ncbi.nlm.nih.gov/34205040/;
DOI: 10.3390/cells10061381
12. Sanjay K Agarwal, Charles Chapron, Linda C Giudice, Marc R Laufer, Nicholas
Leyland, Stacey A Missmer, Sukhbir S Singh, Hugh S Taylor; https://
pubmed.ncbi.nlm.nih.gov/30625295/; DOI: 10.1016/j.ajog.2018.12.039
13. Edgardo Rolla; https://pubmed.ncbi.nlm.nih.gov/31069056/; DOI: 10.12688/
f1000research.14817.1
14. Hafiz Muhammad Arsalan, Hina Mumtaz, Antonio Simone Lagana; https://
pubmed.ncbi.nlm.nih.gov/40185537/; DOI: 10.1016/bs.acc.2025.01.004
15. Elma Pašalić, Murtaza M Tambuwala, Altijana Hromić-Jahjefendić; https://
pubmed.ncbi.nlm.nih.gov/37844487/; DOI: 10.1016/j.prp.2023.154847
16. Mauricio S Abrao, Marina Paula Andres, Charles E Miller, Julian A Gingold, Mariona
Rius, Joao Siufi Neto, Francisco Carmona; https://pubmed.ncbi.nlm.nih.gov/
34583009/; DOI: 10.1016/j.jmig.2021.09.709
17. Jörg Keckstein, Gernot Hudelist; https://pubmed.ncbi.nlm.nih.gov/33558167/; DOI:
10.1016/j.bpobgyn.2020.11.004
18. Giulia Bonavina, Hugh S Taylor; https://pubmed.ncbi.nlm.nih.gov/36387918/; DOI:
10.3389/fendo.2022.1020827
19. Patricia Ribeiro de Carvalho França, Anna Carolina Pereira Lontra, Patricia Dias
Fernandes; https://pubmed.ncbi.nlm.nih.gov/35807280/; DOI: 10.3390/
molecules27134034
20. Matthew Latham Macer, Hugh S Taylor; https://pubmed.ncbi.nlm.nih.gov/23182559/;
DOI: 10.1016/j.ogc.2012.10.002
21. Rui Qin, Gengren Tian, Junbao Liu, Lu Cao; https://pubmed.ncbi.nlm.nih.gov/
36506023/; DOI: 10.3389/fcimb.2022.1069557
22. Anjeza Xholli, Francesca Cremonini, Isabella Perugi, Ambrogio Pietro Londero,
Angelo Cagnacci; https://pubmed.ncbi.nlm.nih.gov/38139822/; DOI: 10.3390/
ph16121696
23. Shiwan Hu, Qiyou Ding, Wei Zhang, Mengjiao Kang, Jing Ma, Linhua Zhao; https://
pubmed.ncbi.nlm.nih.gov/37559394/; DOI: 10.1080/19490976.2023.2236749
24. Isabella Weber, Anna Sienko, Aleksandra Urban, Carolyn Szwed, Krzysztof
Czajkowski, Pawel Basta, Jacek Sienko; https://pubmed.ncbi.nlm.nih.gov/37772919/;
DOI: 10.5603/gpl.97581
25. Meng-Yao Wang, Li-Xuan Sang, Si-Yu Sun; https://pubmed.ncbi.nlm.nih.gov/
38617735/; DOI: 10.3748/wjg.v30.i12.1655
26. Chandni Talwar, Vertika Singh, Ramakrishna Kommagani; https://
pubmed.ncbi.nlm.nih.gov/35878972/; DOI: 10.1093/biolre/ioac147
27. Gianluca Quaranta, Maurizio Sanguinetti, Luca Masucci; https://
pubmed.ncbi.nlm.nih.gov/31827467/; DOI: 10.3389/fimmu.2019.02653
28. Mary E Salliss, Leslie V Farland, Nichole D Mahnert, Melissa M Herbst-Kralovetz;
https://pubmed.ncbi.nlm.nih.gov/34718567/; DOI: 10.1093/humupd/dmab035
29. Tamy Colonetti, Maria Carolina Saggioratto, Antonio José Grande, Laura Colonetti,
João Carlos Denoni Junior, Luciane Bisognin Ceretta, Leonardo Roever, Fábio Rosa
Silva, Maria Inês da Rosa; https://pubmed.ncbi.nlm.nih.gov/38601772/; DOI:
10.1155/2023/2675966
30. Philippe R Koninckx, Anastasia Ussia, Leila Adamyan, Arnaud Wattiez, Victor
Gomel, Dan C Martin; https://pubmed.ncbi.nlm.nih.gov/30527836/; DOI: 10.1016/
j.fertnstert.2018.10.013
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