A Literature Review: Effects of Bariatric Surgery on Adolescents and Young Adults
DOI:
https://doi.org/10.12775/QS.2025.43.61365Keywords
Bariatric surgery, Obesity, adolescent obesityAbstract
Introduction and Purpose: The global rise in adolescent obesity presents a critical public health challenge. Bariatric surgery has emerged as a treatment option for adolescents with severe obesity, especially when conservative interventions fail. This section outlines the rationale for evaluating bariatric surgery outcomes in young patients.
A Brief Description of the State of Knowledge: Studies show that bariatric surgery in adolescents leads to significant and sustained weight loss, resolution of comorbidities such as type 2 diabetes and hypertension, and improvements in quality of life. However, concerns remain about nutritional deficiencies, bone health, and psychological outcomes, highlighting the importance of careful patient selection and multidisciplinary follow-up.
Conclusions: Bariatric surgery can be an effective intervention for adolescents with severe obesity, providing numerous health benefits when other treatments are unsuccessful. Long-term monitoring and ethical considerations are essential for optimizing outcomes and ensuring safety in this vulnerable population.
References
1. Ogle SB, Dewberry LC, Jenkins TM, Inge TH, Kelsey M, Bruzoni M, Pratt JSA. Outcomes of Bariatric Surgery in Older Versus Younger Adolescents. Pediatrics. 2021 Mar;147(3):e2020024182. doi: 10.1542/peds.2020-024182. Epub 2021 Feb 1. PMID: 33526606; PMCID: PMC7919111
2. Bezerra A, Boppre G, Freitas L, Battista F, Duregon F, Faggian S, Busetto L, Ermolao A, Fonseca H. Body Composition Changes in Adolescents Who Underwent Bariatric Surgery: A Systematic Review and Meta-analysis. Curr Obes Rep. 2024 Mar;13(1):107-120. doi: 10.1007/s13679-023-00549-6. Epub 2024 Jan 3. PMID: 38172484; PMCID: PMC10933211
3. Roebroek YGM, Paulus GF, Talib A, van Mil EGAH, Vreugdenhil ACE, Winkens B, Stehouwer CDA, Greve JM, Bouvy ND, van Heurn LWE. Weight Loss and Glycemic Control After Bariatric Surgery in Adolescents With Severe Obesity: A Randomized Controlled Trial. J Adolesc Health. 2024 Mar;74(3):597-604. doi: 10.1016/j.jadohealth.2023.10.024. Epub 2023 Dec 9. PMID: 38069930
4. Aryannezhad S, Hosseinpanah F, Khalaj A, Mahdavi M, Valizadeh M, Akhavirad SMB, Barzin M. Comparison of the one-year outcomes of bariatric surgery in adolescents and young adults: a matched case-control study, Tehran Obesity Treatment Study (TOTS). Surg Today. 2021 Nov;51(11):1764-1774. doi: 10.1007/s00595-021-02281-x. Epub 2021 Apr 10. PMID: 33839932
5. Zeller MH, Kidwell KM, Reiter-Purtill J, Jenkins TM, Michalsky MP, Mitchell JE, Courcoulas AP, Inge TH. Cigarette Use and Adolescent Metabolic and Bariatric Surgery. Obesity (Silver Spring). 2021 Mar;29(3):579-586. doi: 10.1002/oby.23084. Epub 2021 Feb 2. PMID: 33528876; PMCID: PMC8023426
6. Reiter-Purtill J, Decker KM, Jenkins TM, Zeller MH. Self-worth and developmental outcomes in young adults after pediatric bariatric surgery. Health Psychol. 2023 Feb;42(2):92-102. doi: 10.1037/hea0001257. Epub 2023 Jan 12. PMID: 36633990; PMCID: PMC9976787
7. Rode JB, Zeineddin SA, Khoury JC, Jenkins TM, Sisley SR, Courcoulas AP, Ryder JR, Michalsky MP, Inge TH. Gastroesophageal Reflux and Gastrointestinal Symptoms After Metabolic and Bariatric Surgery in Adolescents: An 8-year Follow-up Analysis. J Pediatr Surg. 2025 Apr;60(4):162215. doi: 10.1016/j.jpedsurg.2025.162215. Epub 2025 Jan 31. PMID: 39933471
8. Suarez L, Skinner AC, Truong T, McCann JR, Rawls JF, Seed PC, Armstrong SC. Advanced Obesity Treatment Selection among Adolescents in a Pediatric Weight Management Program. Child Obes. 2022 Jun;18(4):237-245. doi: 10.1089/chi.2021.0190. Epub 2021 Nov 9. PMID: 34757829; PMCID: PMC9145572
9. Kaur S, Nimmala S, Singhal V, Mitchell DM, Pedreira CC, Lauze M, Lee H, Stanford FC, Bouxsein ML, Bredella MA, Misra M. Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes. Eur J Endocrinol. 2023 Sep 1;189(3):346-354. doi: 10.1093/ejendo/lvad121. PMID: 37633255; PMCID: PMC11188938
10. Zeller MH, Strong H, Reiter-Purtill J, Jenkins TM, Mitchell JE, Michalsky MP, Helmrath MA. Marijuana, e-cigarette, and tobacco product use in young adults who underwent pediatric bariatric surgery. Surg Obes Relat Dis. 2023 May;19(5):512-521. doi: 10.1016/j.soard.2022.11.008. Epub 2022 Nov 19. PMID: 36567232; PMCID: PMC10461174
11. Brandt S, Lennerz BS, Wiegand S, Schirmer M, Kleger P, Weyhreter H, Holle R, Hüttl TP, Dietl O, von Schnurbein J, Holl RW, Wabitsch M. Twelve-Month Outcomes after Metabolic and Bariatric Surgery among Youths Participating in a Structured Preparation and Follow-Up Program: Results of the Youth with Extreme Obesity Study. Obes Facts. 2024;17(1):59-71. doi: 10.1159/000535104. Epub 2023 Dec 11. PMID: 38081152; PMCID: PMC10836940
12. Williams D, Chaves E, McKnight E, Eneli I. Diagnostic and treatment challenges of eating disorders after adolescent bariatric surgery: A case report. Clin Obes. 2020 Aug;10(4):e12367. doi: 10.1111/cob.12367. Epub 2020 May 11. PMID: 32394622
13. Sacks MA, Hunter C, Javid PJ, Shakhsheer BA. Contemporary Ethical Considerations for Pediatric Metabolic and Bariatric Surgery. J Pediatr Surg. 2025 Mar;60(3):161988. doi: 10.1016/j.jpedsurg.2024.161988. Epub 2024 Oct 9. PMID: 39455363
14. Hjelmesæth J, Hertel JK, Holt AH, Benestad B, Seeberg LT, Lindberg M, Halvorsen E, Júlíusson PB, Sandbu R, Lekhal S. Laparoscopic gastric bypass versus lifestyle intervention for adolescents with morbid obesity. Tidsskr Nor Laegeforen. 2020 Nov 9;140(16). English, Norwegian. doi: 10.4045/tidsskr.20.0526. PMID: 33172240
15. Mitchell DM, Singhal V, Animashaun A, Bose A, Carmine B, Stanford FC, Inge TH, Kelsey MM, Lee H, Bouxsein ML, Yu EW, Bredella MA, Misra M. Skeletal Effects of Sleeve Gastrectomy in Adolescents and Young Adults: A 2-Year Longitudinal Study. J Clin Endocrinol Metab. 2023 Mar 10;108(4):847-857. doi: 10.1210/clinem/dgac634. PMID: 36314507; PMCID: PMC10211497
16. Misra M, Singhal V, Carmine B, Bose A, Kelsey MM, Stanford FC, Bram J, Aidlen J, Inge T, Bouxsein ML, Bredella MA. Bone outcomes following sleeve gastrectomy in adolescents and young adults with obesity versus non-surgical controls. Bone. 2020 May;134:115290. doi: 10.1016/j.bone.2020.115290. Epub 2020 Feb 19. PMID: 32084562; PMCID: PMC7138705
17. Nimmala S, Kaur S, Singhal V, Mitchell DM, Stanford FC, Bouxsein ML, Lauze M, Huynh C, Pedreira CC, Lee H, Bredella MA, Misra M. Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters. J Clin Endocrinol Metab. 2022 Aug 18;107(9):e3747-e3758. doi: 10.1210/clinem/dgac361. PMID: 35689793; PMCID: PMC9387701
18. Bonouvrie DS, Beamish AJ, Leclercq WKG, van Mil EGAH, Luijten AAPM, Hazebroek EJ, Vreugdenhil ACE, Olbers T, van Dielen FMH. Laparoscopic roux-en-Y gastric bypass versus sleeve gastrectomy for teenagers with severe obesity - TEEN-BEST: study protocol of a multicenter randomized controlled trial. BMC Surg. 2020 Jun 3;20(1):117. doi: 10.1186/s12893-020-00778-9. PMID: 32493359; PMCID: PMC7268239
19. Brehm B, Summer S, Jenkins T, D'Alessio D, Inge T. Thermic effect of food and resting energy expenditure after sleeve gastrectomy for weight loss in adolescent females. Surg Obes Relat Dis. 2020 May;16(5):599-606. doi: 10.1016/j.soard.2020.01.025. Epub 2020 Feb 4. PMID: 32146085; PMCID: PMC7370941
20. Baskaran C, Bose A, Plessow F, Torre Flores L, Toth AT, Eddy KT, Bredella MA, Misra M. Depressive and anxiety symptoms and suicidality in adolescent and young adult females with moderate to severe obesity before and after weight loss surgery. Clin Obes. 2020 Oct;10(5):e12381. doi: 10.1111/cob.12381. Epub 2020 Jun 18. PMID: 32558297; PMCID: PMC8678933
21. Weiner A, Cowell A, McMahon DJ, Tao R, Zitsman J, Oberfield SE, Fennoy I. The effects of adolescent laparoscopic adjustable gastric band and sleeve gastrectomy on markers of bone health and bone turnover. Clin Obes. 2020 Dec;10(6):e12411. doi: 10.1111/cob.12411. Epub 2020 Sep 7. PMID: 32896095; PMCID: PMC7935448
22. Gensthaler L, Felsenreich DM, Jedamzik J, Eichelter J, Nixdorf L, Bichler C, Krebs M, Itariu B, Langer FB, Prager G. Trends of Overweight and Obesity in Male Adolescents: Prevalence, Socioeconomic Status, and Impact on Cardiovascular Risk in a Central European Country. Obes Surg. 2022 Apr;32(4):1024-1033. doi: 10.1007/s11695-021-05867-z. Epub 2022 Jan 18. PMID: 35041124; PMCID: PMC8933384
23. Vidmar AP, Kaiser L, Martin MJ, Abel S, Kim AG, Weitzner M, Muñoz CE, Fisher LK, Kim MS, Samakar K. Semaglutide and laparoscopic sleeve gastrectomy in an adolescent with congenital adrenal hyperplasia due to 21-hydroxylase: a case report. J Med Case Rep. 2025 Jan 25;19(1):37. doi: 10.1186/s13256-025-05047-y. PMID: 39863876; PMCID: PMC11765928
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Natalia Katarzyna Wagner-Bieleń, Martyna Zwierzchowska, Agata Antoniak, Anna Maria Jocz, Anna Centkowska, Joanna Karina Banaśkiewicz, Aleksandra Maria Żyta, Gabriela Helena Dąbrowska, Maria Anna Żmijewska, Jakub Ziółkowski

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Stats
Number of views and downloads: 229
Number of citations: 0