Environmental Risk Factors of Psychosis: A Review
DOI:
https://doi.org/10.12775/QS.2025.41.60262Keywords
Psychosis, risk factors, environmental factor, schizophrenia, traumaAbstract
Psychosis is a severe mental health condition that can be debilitating for a person's well-being. It is characterized by disturbances in perception, emotional regulation and thought processes, including symptoms like hallucinations and delusions, leading to a disconnection from reality. Patients often suffer when trying to meet the demands of ordinary life. Genetic predisposition plays a significant role in development of psychosis. Besides these, there are also environmental influences, which contribute as a trigger and later progression of psychotic disorders. These external determinants could possibly be managed in attempts to contain the problem of increased mental health conditions with the main psychotic component. This article reviews the literature reports of current environmental risk factors of psychosis. The keyword used was “psychosis” searched alone or in combination with “risk factors”, “environmental factors” or “external factors”.
References
1. Radua J, Ramella-Cravaro V, Ioannidis JPA, Reichenberg A, Phiphopthatsanee N, Amir T, Yenn Thoo H, Oliver D, Davies C, Morgan C, McGuire P, Murray RM, Fusar-Poli P. What causes psychosis? An umbrella review of risk and protective factors. World Psychiatry. 2018 Feb;17(1):49-66. doi: 10.1002/wps.20490. PMID: 29352556; PMCID: PMC5775150.
2. Fett AJ, Lemmers-Jansen ILJ, Krabbendam L. Psychosis and urbanicity: a review of the recent literature from epidemiology to neurourbanism. Curr Opin Psychiatry. 2019 May;32(3):232-241. doi: 10.1097/YCO.0000000000000486. PMID: 30724751; PMCID: PMC6493678.
3. Attademo L, Bernardini F, Garinella R, Compton MT. Environmental pollution and risk of psychotic disorders: A review of the science to date. Schizophr Res. 2017 Mar;181:55-59. doi: 10.1016/j.schres.2016.10.003. Epub 2016 Oct 6. PMID: 27720315.
4. Braithwaite I, Zhang S, Kirkbride JB, Osborn DPJ, Hayes JF. Air Pollution (Particulate Matter) Exposure and Associations with Depression, Anxiety, Bipolar, Psychosis and Suicide Risk: A Systematic Review and Meta-Analysis. Environ Health Perspect. 2019 Dec;127(12):126002. doi: 10.1289/EHP4595. Epub 2019 Dec 18. PMID: 31850801; PMCID: PMC6957283.
5. Beards S, Gayer-Anderson C, Borges S, Dewey ME, Fisher HL, Morgan C. Life events and psychosis: a review and meta-analysis. Schizophr Bull. 2013 Jul;39(4):740-7. doi: 10.1093/schbul/sbt065. Epub 2013 May 13. PMID: 23671196; PMCID: PMC3686461.
6. Hollander AC, Dal H, Lewis G, Magnusson C, Kirkbride JB, Dalman C. Refugee migration and risk of schizophrenia and other non-affective psychoses: cohort study of 1.3 million people in Sweden. BMJ. 2016 Mar 15;352:i1030. doi: 10.1136/bmj.i1030. Erratum in: BMJ. 2016 May 27;353:i2865. doi: 10.1136/bmj.i2865. PMID: 26979256; PMCID: PMC4793153.
7. Stilo SA, Murray RM. Non-Genetic Factors in Schizophrenia. Curr Psychiatry Rep. 2019 Sep 14;21(10):100. doi: 10.1007/s11920-019-1091-3. PMID: 31522306; PMCID: PMC6745031.
8. Di Forti M, Quattrone D, Freeman TP, Tripoli G, Gayer-Anderson C, Quigley H, Rodriguez V, Jongsma HE, Ferraro L, La Cascia C, La Barbera D, Tarricone I, Berardi D, Szöke A, Arango C, Tortelli A, Velthorst E, Bernardo M, Del-Ben CM, Menezes PR, Selten JP, Jones PB, Kirkbride JB, Rutten BP, de Haan L, Sham PC, van Os J, Lewis CM, Lynskey M, Morgan C, Murray RM; EU-GEI WP2 Group. The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study. Lancet Psychiatry. 2019 May;6(5):427-436. doi: 10.1016/S2215-0366(19)30048-3. Epub 2019 Mar 19. PMID: 30902669; PMCID: PMC7646282.
9. Sara GE, Large MM, Matheson SL, Burgess PM, Malhi GS, Whiteford HA, Hall WD. Stimulant use disorders in people with psychosis: a meta-analysis of rate and factors affecting variation. Aust N Z J Psychiatry. 2015 Feb;49(2):106-17. doi: 10.1177/0004867414561526. Epub 2014 Dec 17. PMID: 25518844.
10. Rauschenberg C, van Os J, Goedhart M, Schieveld JNM, Reininghaus U. Bullying victimization and stress sensitivity in help-seeking youth: findings from an experience sampling study. Eur Child Adolesc Psychiatry. 2021 Apr;30(4):591-605. doi: 10.1007/s00787-020-01540-5. Epub 2020 May 13. PMID: 32405792; PMCID: PMC8041697.
11. Lipner E, O'Brien KJ, Pike MR, Ered A, Ellman LM. Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity. Curr Top Behav Neurosci. 2023;63:205-240. doi: 10.1007/7854_2022_378. PMID: 35915384; PMCID: PMC9892366.
12. Read J, van Os J, Morrison AP, Ross CA. Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications. Acta Psychiatr Scand. 2005 Nov;112(5):330-50. doi: 10.1111/j.1600-0447.2005.00634.x. PMID: 16223421.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Bartosz Jagieła, Michał Bolek, Monika Fidyk, Aleksandra Kędzia, Dominika Musialska, Magda Minkiewicz

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Stats
Number of views and downloads: 22
Number of citations: 0