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Quality in Sport

Health Implications of Anabolic-Androgenic Steroids: Usage, Risks, and Treatment Approaches - The Literature Review
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Health Implications of Anabolic-Androgenic Steroids: Usage, Risks, and Treatment Approaches - The Literature Review

Authors

  • Krzysztof Jodłowski Hospital of the Ministry of Interior and Administration in Lodz, ul. Północna 42, 91–425 Łódź: Lodz, lodzkie, PL https://orcid.org/0009-0003-9041-2091
  • Ewa Dubniewicz Central Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Lodz https://orcid.org/0009-0007-4191-6794
  • Paula Majewska Central Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Lodz https://orcid.org/0009-0003-7934-397X
  • Alicja Staszek Central Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Lodz https://orcid.org/0009-0007-0323-8697
  • Wiktoria Łoskot University Clinical Hospital No. 2 of the Medical University of Lodz: Łódź, ul. Stefana Żeromskiego 113, 90-549 Łódź https://orcid.org/0009-0001-5392-4835
  • Jan Szwech Masovian Specialist Hospital in Radom, ul. Aleksandrowicza 5; 26-617 Radom https://orcid.org/0009-0002-9312-8152
  • Mateusz Matczak Hospital of the Ministry of Interior and Administration in Lodz, ul. Północna 42, 91–425 Łódź: Lodz, lodzkie, PL https://orcid.org/0009-0000-9701-406X
  • Karol Jasiński Provincial Hospital of St. Luke, 33-100 Tarnów, ul. Lwowska 178a https://orcid.org/0009-0004-6845-5199
  • Aleksandra Broda Hospital of the Ministry of Interior and Administration in Lodz, ul. Północna 42, 91–425 Łódź: Lodz, lodzkie, PL https://orcid.org/0009-0004-5179-9411
  • Kacper Hoksa Hospital of the Ministry of Interior and Administration in Lodz, ul. Północna 42, 91–425 Łódź: Lodz, lodzkie, PL https://orcid.org/0009-0007-9832-7093

DOI:

https://doi.org/10.12775/QS.2025.38.57914

Keywords

anabolic-androgenic steroids, AAS, androgens, hypogonadism, infertility, erectile dysfunction, testicular atrophy, performance enhancing drugs, PED

Abstract

Anabolic-androgenic steroids (AAS) are commonly used to enhance athletic performance and physical appearance, but their abuse is linked to a range of serious health consequences, including cardiovascular, liver, and psychological disorders, as well as infertility. Despite the growing concern over AAS misuse, current research is limited by methodological constraints, including a lack of randomized controlled trials and long-term studies. The review explores the health implications of AAS use, highlighting the importance of an interdisciplinary approach to managing AAS-related health issues, emphasizing harm reduction, pharmacological interventions, and fertility preservation techniques. It also underscores the need for improved healthcare support, education, and trust-building to address the challenges associated with AAS abuse effectively.

Furthermore, the review highlights significant gaps in the literature, such as the absence of comprehensive guidelines for harm reduction and the scarcity of longitudinal data on the long-term effects of AAS. The findings suggest a critical need for continued research, better medical management, and societal interventions to mitigate the risks associated with AAS use and provide effective care for affected individuals.

References

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2. Handelsman, D. J. Androgen Misuse and Abuse. Endocrine Reviews vol. 42 457–501 Preprint at https://doi.org/10.1210/endrev/bnab001 (2021).

3. Bond, P., Smit, D. L. & de Ronde, W. Anabolic–androgenic steroids: How do they work and what are the risks? Frontiers in Endocrinology vol. 13 Preprint at https://doi.org/10.3389/fendo.2022.1059473 (2022).

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19. Bond, P., Llewellyn, W. & Van Mol, P. Anabolic androgenic steroid-induced hepatotoxicity. Med Hypotheses 93, 150–153 (2016).

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Published

2025-02-11

How to Cite

1.
JODŁOWSKI, Krzysztof, DUBNIEWICZ, Ewa, MAJEWSKA, Paula, STASZEK, Alicja, ŁOSKOT, Wiktoria, SZWECH, Jan, MATCZAK, Mateusz, JASIŃSKI, Karol, BRODA, Aleksandra and HOKSA, Kacper. Health Implications of Anabolic-Androgenic Steroids: Usage, Risks, and Treatment Approaches - The Literature Review. Quality in Sport. Online. 11 February 2025. Vol. 38, p. 57914. [Accessed 26 December 2025]. DOI 10.12775/QS.2025.38.57914.
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Vol. 38 (2025)

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Medical Sciences

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Copyright (c) 2025 Krzysztof Jodłowski, Ewa Dubniewicz, Paula Majewska, Alicja Staszek, Wiktoria Łoskot, Jan Szwech, Mateusz Matczak, Karol Jasiński, Aleksandra Broda, Kacper Hoksa

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