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Quality in Sport

Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review
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  • Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review
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Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review

Authors

  • Katarzyna Barabasz Jagiellonian University Medical College, Świętej Anny 12, 31-008 Kraków https://orcid.org/0009-0009-0696-7697
  • Paulina Więcławek Jagiellonian University Medical College, Świętej Anny 12, 31-008 Kraków https://orcid.org/0009-0009-3389-0920
  • Piotr Juda SP ZOZ MSWiA in Kraków, Kronikarza Galla 25, 30-053 Kraków https://orcid.org/0009-0005-0940-3871
  • Patrycja Kłaptocz Szpital Wojewódzki w Bielsku-Białej, aleja Armii Krajowej 101, 43-316 Bielsko-Biała https://orcid.org/0009-0001-3324-0321
  • Katarzyna Łukoś-Karcz Szpital Wojewódzki w Bielsku-Białej, aleja Armii Krajowej 101, 43-316 Bielsko-Biała https://orcid.org/0009-0004-6690-6507
  • Dominik Bańkowski Medical University of Lublin, Aleje Racławickie 1, 20-059 Lublin https://orcid.org/0009-0008-9439-3103
  • Gabriela Pabian Jagiellonian University Medical College, Świętej Anny 12, 31-008 Kraków https://orcid.org/0009-0009-0468-4589
  • Karol Musiał Jagiellonian University Medical College, Świętej Anny 12, 31-008 Kraków https://orcid.org/0009-0008-2277-5508
  • Kamil Bielak Medical University of Lublin, Aleje Racławickie 1, 20-059 Lublin https://orcid.org/0009-0002-2280-0116

DOI:

https://doi.org/10.12775/QS.2025.37.57776

Keywords

Alzheimer's disease, Physical activity, intensive exercise, cognitive functions, biomarkers, BDNF, Quality of life, neuroplasticity

Abstract

Objective

Alzheimer’s Disease (AD) is the most common form of dementia, representing a global health challenge. The aim of this review is to assess the impact of different types and intensities of physical exercise on cognitive functions, biomarkers, and the quality of life of AD patients.

 

Methods

Studies from PubMed, Scopus, Cochrane Library, and Web of Science (2000–2024) were analyzed, focusing on the effects of aerobic, resistance, and combined exercises on memory, executive functions, biomarkers (amyloid beta, tau protein, BDNF), daily living abilities (ADL), and quality of life. The review included 42 studies, including randomized controlled trials and meta-analyses.

 

Results

Moderate-intensity aerobic and combined exercises improve memory and executive functions, while resistance training increases hippocampal volume, supporting spatial memory. High-intensity exercises boost BDNF levels, and moderate-intensity exercises reduce neurodegenerative biomarkers and improve ADL.

 

Conclusions

Moderate aerobic and combined exercises are effective in preventing and supporting AD therapy. Further research is needed to standardize exercise protocols and evaluate their long-term effects.

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Published

2025-01-27

How to Cite

1.
BARABASZ, Katarzyna, WIĘCŁAWEK, Paulina, JUDA, Piotr, KŁAPTOCZ, Patrycja, ŁUKOŚ-KARCZ, Katarzyna, BAŃKOWSKI, Dominik, PABIAN, Gabriela, MUSIAŁ, Karol and BIELAK, Kamil. Assessment of the Impact of Different Types and Intensities of Physical Exercise on the Quality of Life of Patients with Alzheimer’s Disease: A Literature Review. Quality in Sport. Online. 27 January 2025. Vol. 37, p. 57776. [Accessed 16 June 2025]. DOI 10.12775/QS.2025.37.57776.
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Vol. 37 (2025)

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Copyright (c) 2025 Katarzyna Barabasz, Paulina Więcławek, Piotr Juda, Patrycja Kłaptocz, Katarzyna Łukoś-Karcz, Dominik Bańkowski, Gabriela Pabian, Karol Musiał, Kamil Bielak

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