The impact of physical activity on mental health
DOI:
https://doi.org/10.12775/QS.2025.37.57234Keywords
Mental disorders, Mental health, Exercises, Sport, Physical activityAbstract
This article critically evaluates the interconnectedness of physical activity and mental health, drawing on a diverse body of evidence from observational studies, controlled trials, and emerging neuroscientific research. We explore how engaging in regular exercise is associated with improved mood regulation, reductions in anxiety and depressive symptoms, and better coping strategies under stress. By examining a range of exercise modalities, intensities, and durations across various age groups and demographic contexts, we shed light on the differential impacts of physical activity on mental well-being. Neuroscientific findings including those from neuroimaging and biomarker analyses offer insights into the biological mechanisms behind these improvements, revealing alterations in neural circuits and neurotransmitter systems that underpin emotional resilience and cognitive functioning. We further consider the psychological and social benefits that accompany regular physical activity, such as enhanced self-esteem, feelings of belonging, and the establishment of positive routines. Finally, we identify gaps in existing research, including the need for more tailored, evidence-based exercise prescriptions and an improved understanding of how to optimize interventions for individuals with specific mental health profiles. Overall, this review underscores the imperative of incorporating strategic physical activity programs into mental health prevention, treatment, and policy initiatives.
References
1. WHO Mental Health: Strengthening Our Response. [(accessed on 13 February 2019)]. Available online: https://www.who.int/news-room/fact-sheets/detail/mental-health-strengthening-our-response
2. Waddington GS. Covid-19, mental health and physical activity. J Sci Med Sport. 2021 Apr;24(4):319. doi: 10.1016/j.jsams.2021.02.009. PMID: 33622583; PMCID: PMC7896494.
3. Peluso MA, Guerra de Andrade LH. Physical activity and mental health: the association between exercise and mood. Clinics (Sao Paulo). 2005 Feb;60(1):61-70. doi: 10.1590/s1807-59322005000100012. Epub 2005 Mar 1. PMID: 15838583.
4. Correll CU, Solmi M, Veronese N, Bortolato B, Rosson S, Santonastaso P, et al. Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls. World Psychiatry. 2017;16:163-80.
5. Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, et al. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet. 2018;391:1357-66.
6. Ostrow L, Jessell L, Hurd M, Darrow SM, Cohen D. Discontinuing psychiatric medications: a survey of long-term users. Psychiatr Serv. 2017;68:1232-38
7. Dimeo F., Bauer M., Varahram I., et al. Benefits from aerobic exercise in patients with major depression: a pilot study Br J Sports Med, 35 (2) (2001), pp. 114-117
8. Hallal PC, Andersen LB, Bull FC, Guthold R, Haskell W, Ekelund ULancet Physical Activity Series Working Group. Global physical activity levels: surveillance progress, pitfalls, and prospects. Lancet 2012;380:247-57. https://doi.org/10.1016/S0140-6736(12)60646-1 10.1016/S0140-6736(12)60646-1
9. European Commission Sport and Physical Activity, Special Eurobarometer 412-2014. Available at https://data.europa.eu/data/datasets/s1116_80_2_412?locale=en. Accessed on: 26/06/2022.
10. Ng SW, Popkin BM. Time use and physical activity: a shift away from movement across the globe. Obes Rev 2012;13:659-80. https://doi.org/10.1111/j.1467-789X.2011.00982.x 10.1111/j.1467-789X.2011.00982.x
11. World Health Organization (WHO) Regional Office for Europe (2012). Health Policy for Children and Adolescents No.6, Health behaviour in school-aged children, International report from the 2009/2010 survey. Copenhagen, Denmark: WHO.
12. Physical Activity for Different Groups. Available at: https://www.cdc.gov/physicalactivity/basics/age-chart.html. Accessed on: 26/06/2022.
13. Ghosh D, Datta TK. Functional improvement and social participation through sports activity for children with mental retardation: a field study from a developing nation Prosthet Orthot Int. 2012;36:339–347. doi: 10.1177/0309364612451206.
14. WP Morgan Affective beneficence of vigorous physical activity Med Sci Sports Exerc, 17 (1985), pp. 94-100
15. AL Dunn, RK Dishman Exercise and the neurobiology of depression Exerc Sport Sci Rev, 19 (1991), pp. 41-98
16. M Allen The psychobiology of athletic training Sport psychiatry: theory and practice, W. W. Norton & Company, New York (2000), pp. 22-44
17. M Greenspan, P Fitzsimmons, S Biddle Aspects of psychology in sports medicine Br J Sports Med, 25 (4) (1991), pp. 178-180
18. Schuch FB, Vancampfort D, Firth J, Rosenbaum S, Ward PB, Silva ES, et al. Physical activity and incident depression: a meta-analysis of prospective cohort studies. Am J Psychiatry. 2018;175:631-48.
19. Cabral P, Meyer HB, Ames D. Effectiveness of yoga therapy as a complementary treatment for major psychiatric disorders: a meta-analysis. Prim Care Companion CNS Disord. 2011;13 doi: 10.4088/PCC.10r01068.
20. Saeed SA, Cunningham K, Bloch RM. Depression and Anxiety Disorders: Benefits of Exercise, Yoga, and Meditation. Am Fam Physician. 2019 May 15;99(10):620-627. PMID: 31083878.
21. Mohammad A, Thakur P, Kumar R, Kaur S, Saini RV, Saini AK. Biological markers for the effects of yoga as a complementary and alternative medicine. J Complement Integr Med. 2019 Feb 7;16(1). doi: 10.1515/jcim-2018-0094. PMID: 30735481.
22. Cramer H, Lauche R, Anheyer D, Pilkington K, de Manincor M, Dobos G, Ward L. Yoga for anxiety: A systematic review and meta-analysis of randomized controlled trials. Depress Anxiety. 2018 Sep;35(9):830-843. doi: 10.1002/da.22762. Epub 2018 Apr 26. PMID: 29697885.
23. Saeed SA, Antonacci DJ, Bloch RM. Exercise, yoga, and meditation for depressive and anxiety disorders. Am Fam Physician. 2010 Apr 15;81(8):981-6. PMID: 20387774.
24. Erickson KI, Hillman C, Stillman CM, Ballard RM, Bloodgood B, Conroy DE, Macko R, Marquez DX, Petruzzello SJ, Powell KE; FOR 2018 physical activity guidelines advisory committee*. Physical Activity, Cognition, and Brain Outcomes: A Review of the 2018 Physical Activity Guidelines. Med Sci Sports Exerc. 2019 Jun;51(6):1242-1251. doi: 10.1249/MSS.0000000000001936. PMID: 31095081; PMCID: PMC6527141.
25. Ghrouz AK, Noohu MM, Dilshad Manzar M, Warren Spence D, BaHammam AS, Pandi-Perumal SR., Physical activity and sleep quality in relation to mental health among college students. Sleep Breath. 2019;23:627–634. doi: 10.1007/s11325-019-01780-z.
26. Sabe M, Sentissi O, Kaiser S. Meditation-based mind-body therapies for negative symptoms of schizophrenia: systematic review of randomized controlled trials and meta-analysis. Schizophr Res. 2019;212:15–25. doi: 10.1016/j.schres.2019.07.030.
27. Babyak M, Blumenthal JA, Herman S, et al., Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months. Psychosom Med. 2000;62:633–638. doi: 10.1097/00006842-200009000-00006.
28. Dishman RK, O’Connor PJ. Lessons in exercise neurobiology: the case of endorphins. Ment. Health Phys. Act. 2009;2(1):4–9.
29. Okuyama J, Seto S, Fukuda Y, Funakoshi S, Amae S, Onobe J, Izumi S, Ito K, Imamura F. Mental Health and Physical Activity among Children and Adolescents during the COVID-19 Pandemic. Tohoku J Exp Med. 2021 Mar;253(3):203-215. doi: 10.1620/tjem.253.203. PMID: 33775993.
30. Phillips C. Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection. Neural Plast. 2017;2017:7260130. doi: 10.1155/2017/7260130. Epub 2017 Aug 8. PMID: 28928987; PMCID: PMC5591905.
31. Zhao JL, Jiang WT, Wang X, Cai ZD, Liu ZH, Liu GR. Exercise, brain plasticity, and depression. CNS Neurosci Ther. 2020 Sep;26(9):885-895. doi: 10.1111/cns.13385. Epub 2020 Jun 3. PMID: 32491278; PMCID: PMC7415205.
32. Imboden C, Claussen MC, Seifritz E, Gerber M. Die Bedeutung von körperlicher Aktivität für die psychische Gesundheit [The Importance of Physical Activity for Mental Health]. Praxis (Bern 1994). 2022;110(4):186-191. German. doi: 10.1024/1661-8157/a003831. PMID: 35291871.
33. Kvam S, Kleppe CL, Nordhus IH, Hovland A. J, Exercise as a treatment for depression: a meta-analysis. Affect Disord. 2016;202:67–86. doi: 10.1016/j.jad.2016.03.063.
34. Jayakody K, Gunadasa S, Hosker C. Exercise for anxiety disorders: systematic review. Br J Sports Med. 2014;48:187–196. doi: 10.1136/bjsports-2012-091287.
35. Vancampfort D, Vandael H, Hallgren M, Probst M, Hagemann N, Bouckaert F, Van Damme T. Physical fitness and physical activity levels in people with alcohol use disorder versus matched healthy controls: A pilot study. Alcohol. 2019 May;76:73-79. doi: 10.1016/j.alcohol.2018.07.014. Epub 2018 Aug 8. PMID: 30584965.
36. Cabé N, Lanièpce A, Pitel AL. Physical activity: A promising adjunctive treatment for severe alcohol use disorder. Addict Behav. 2021 Feb;113:106667. doi: 10.1016/j.addbeh.2020.106667. Epub 2020 Sep 29. PMID: 33074123.
37. Hallgren M, Andersson V, Ekblom Ö, Andréasson S. Physical activity as treatment for alcohol use disorders (FitForChange): study protocol for a randomized controlled trial. Trials. 2018;19:106. doi: 10.1186/s13063-017-2435-0.
38. Lardier DT, Coakley KE, Holladay KR, Amorim FT, Zuhl MN. Exercise as a useful intervention to reduce alcohol consumption and improve physical fitness in individuals with alcohol use disorder: a systematic review and meta-analysis. Front Psychol. 2021;12:675285. doi: 10.3389/fpsyg.2021.675285.
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Copyright (c) 2025 Natalia Myśliwiec, Aleksandra Ciesielska, Marta Wojtczak, Aleksandra Sieradzka, Alicja Kot, Adrian Różycki, Michał Pniak, Maciej Mawlichanów, Paweł Miklis, Krzysztof Szerej
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