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Quality in Sport

Imaging Diagnostics, Biomarkers, and Emerging Trends in Orthopedic Research and Treatment
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Imaging Diagnostics, Biomarkers, and Emerging Trends in Orthopedic Research and Treatment

Authors

  • Gabriela Trestka Clinical Provincial Hospital No 2 in Rzeszów, Poland https://orcid.org/0009-0009-9504-8923
  • Wiktoria Domino Clinical Provincial Hospital No. 2 in Rzeszów, Poland Lwowska 60, 35-501 Rzeszów, Poland https://orcid.org/0009-0005-0034-7463
  • Urszula Zelik University Teaching Hospital them F. Chopin in Rzeszów, Poland Fryderyka Szopena 2, 35-055 Rzeszów, Poland https://orcid.org/0009-0009-3369-7936
  • Maria Przygoda Specialist Hospital named after Stefan Żeromski, Independent Public Healthcare Facility (SP ZOZ), in Kraków https://orcid.org/0000-0002-6409-7265
  • Joanna Śnieżna Medical University of Lublin: Lublin, Poland https://orcid.org/0009-0006-2713-0835
  • Kamila Stępień Independent Public Health Care Facility of the Ministry of Internal Affairs and Administration in Kielce, Poland Wojska Polskiego 51, 25-375 Kielce, Poland https://orcid.org/0009-0000-3579-9308
  • Sabina Adamczyk Independent Public Healthcare Facility of the Ministry of Internal Affairs and Administration in Opole, Poland https://orcid.org/0009-0003-9671-6619
  • Wojciech Florczak Medical University of Lublin: Lublin, Poland https://orcid.org/0009-0006-8003-0999
  • Jagienka Włodyka University Teaching Hospital them F. Chopin in Rzeszów, Poland Fryderyka Szopena 2, 35-055 Rzeszów, Poland https://orcid.org/0009-0000-7243-7023
  • Jakub Dziewic Medical University of Lublin: Lublin, Poland https://orcid.org/0009-0008-4338-4573
  • Karol Dzwonnik Medical University of Lublin: Lublin, Poland https://orcid.org/0009-0007-1366-3945

DOI:

https://doi.org/10.12775/QS.2025.37.57103

Keywords

orthopedics, x-ray, computed tomography, magnetic resonans imaging, biomarkers, imaging diagnostics

Abstract

With an aging population, increasing sports participation, and a rising number of obese individuals, researchers are addressing the growing prevalence of musculoskeletal diseases. Early diagnosis is crucial for effective treatment and disease prevention. Imaging techniques and biomarkers are essential tools in orthopedic diagnostics, providing critical insights into disease progression, treatment efficacy, and clinical outcomes prediction.

This paper offers an overview of key imaging modalities, including X-ray, CT, MRI, ultrasonography, scintigraphy, and fluorescence tomography (FLAIR), highlighting their strengths, limitations, and clinical applications. X-ray and CT are commonly used for bone-related issues, while MRI and ultrasonography are invaluable for evaluating soft tissues. Scintigraphy and FLAIR, on the other hand, are particularly effective for detecting metabolic activity and soft tissue changes.

Biomarkers, such as those used in osteoarthritis, osteoporosis, joint inflammation, and bone regeneration, complement imaging techniques by enabling early diagnosis, monitoring disease progression, and predicting treatment outcomes. The integration of biomarkers with imaging provides a more comprehensive approach to patient care.

Finally, emerging technologies like artificial intelligence, smartphones, 4DCT, and 3D printing of implants are poised to revolutionize orthopedic diagnostics and treatment. These advancements promise greater precision in diagnostics, personalized treatments, and improved patient outcomes, though challenges in implementation and technology adoption remain.

References

1. Gutman, Michael J., Gregory D. Schroeder, Hamadi A. Murphy, Adam E. Flanders and Alexander R. Vaccaro. “Artificial Intelligence in Spine Care.” Clinical Spine Surgery 34 (2020): 121 - 124.

2. Martin RK, Ley C, Pareek A, Groll A, Tischer T, Seil R. Artificial intelligence and machine learning: an introduction for orthopaedic surgeons. Knee Surgery, Sports Traumatology, Arthroscopy. 2022 Feb;30(2):361-364. doi: 10.1007/s00167-021-06741-2

3. Al-Hadithy N, Gikas PD, Al-Nammari SS. Smartphones in orthopaedics. Int Orthop. 2012 Aug;36(8):1543-7. doi: 10.1007/s00264-012-1527-4. Epub 2012 Mar 17. PMID: 22426935; PMCID: PMC3535034.

4. Saggi SS, Kuah LZD, Toh LCA, Shah MTBM, Wong MK, Bin Abd Razak HR. Optimisation of postoperative X-ray acquisition for orthopaedic patients. BMJ Open Qual. 2022 Mar;11(1):e001216. doi: 10.1136/bmjoq-2020-001216. PMID: 35354599; PMCID: PMC8968530.

5. Kostopoulos D, Rawat M. Musculoskeletal ultrasound in orthopedic practice. J Bodyw Mov Ther. 2019 Oct;23(4):815-817. doi: 10.1016/j.jbmt.2019.09.008. Epub 2019 Oct 1. PMID: 31733766.

6. Szymański T, Zdanowicz U. Comparison of routine computed tomography and plain X-ray imaging for malleolar fractures-How much do we miss? Foot Ankle Surg. 2022 Feb;28(2):263-268. doi: 10.1016/j.fas.2021.03.025. Epub 2021 Apr 1. PMID: 33832814.

7. Sawyer JR. Radiation Reduction Strategies in Pediatric Orthopaedics. J Pediatr Orthop. 2021 Jul 1;41(Suppl 1):S75-S79. doi: 10.1097/BPO.0000000000001822. PMID: 34096542.Miller BJ, Avedian RS, Rajani R, Leddy L, White JR, Cummings J, Balach T, MacDonald K;

8. Musculoskeletal Oncology Research Initiative. What is the use of imaging before referral to an orthopaedic oncologist? A prospective, multicenter investigation. Clin Orthop Relat Res. 2015 Mar;473(3):868-74. doi: 10.1007/s11999-014-3649-z. PMID: 24777726; PMCID: PMC4317449.

9. Jungmann PM, Agten CA, Pfirrmann CW, Sutter R. Advances in MRI around metal. J Magn Reson Imaging. 2017 Oct;46(4):972-991. doi: 10.1002/jmri.25708. Epub 2017 Mar 25. PMID: 28342291.

10. Lee JW, Chang SH, Jang SJ, Park HJ, Lee SM, Jung KJ. Clinical utility of quantitative analysis of bone scintigraphy in detecting clinically active joint and high disease activity in patients with rheumatoid arthritis. BMC Med Imaging. 2021 Nov 23;21(1):177. doi: 10.1186/s12880-021-00712-2. PMID: 34814863; PMCID: PMC8611961.

11. Zhou J, Huang J, Li Z, Song Q, Yang Z, Wang L, Meng Q. Identification of aging-related biomarkers and immune infiltration characteristics in osteoarthritis based on bioinformatics analysis and machine learning. Front Immunol. 2023 Jul 12;14:1168780. doi: 10.3389/fimmu.2023.1168780. PMID: 37503333; PMCID: PMC10368975.

12. Chen FP, Fu TS, Lin YC, Sung CM, Huang MH, Lin YJ. Association between P1NP and bone strength in postmenopausal women treated with teriparatide. Taiwan J Obstet Gynecol. 2022 Jan;61(1):91-95. doi: 10.1016/j.tjog.2021.11.017. PMID: 35181054.

13. 1. Jorge PB, Sprey JWC, Runco GM, Lima MV de, Severino NR, Santili C. Difference in Articular Degeneration Depending on the Type of Sport. Rev bras ortop [Internet]. 2019Sep;54(5):509–15. Available from: https://doi.org/10.1016/j.rboe.2018.02.012

14. Deng ZH, Li YS, Gao X, Lei GH, Huard J. Bone morphogenetic proteins for articular cartilage regeneration. Osteoarthritis Cartilage. 2018 Sep;26(9):1153-1161. doi: 10.1016/j.joca.2018.03.007. Epub 2018 Mar 24. PMID: 29580979.

15. Costa, V., Terrando, S., Bellavia, D. et al. MiR203a-3p as a potential biomarker for synovial pathology associated with osteoarthritis: a pilot study. J Orthop Surg Res 19, 746 (2024). https://doi.org/10.1186/s13018-024-05237-2

16. Meng M, Wang J, Huang H, Liu X, Zhang J, Li Z. 3D printing metal implants in orthopedic surgery: Methods, applications and future prospects. J Orthop Translat. 2023 Sep 1;42:94-112. doi: 10.1016/j.jot.2023.08.004. PMID: 37675040; PMCID: PMC10480061.

17. Wong MT, Wiens C, Kuczynski M, Manske S, Schneider PS. Four-dimensional computed tomography: musculoskeletal applications. Can J Surg. 2022 Jun 14;65(3):E388-E393. doi: 10.1503/cjs.023420. PMID: 35701004; PMCID: PMC9200445.

18. Kalenderer O, Erkus S, Sarikaya IA, Turgut A, Inan M. The MRI Effect in Clinical Decision Process in Perthes' Disease: "More Complex Imaging, More Complicated Surgeries". Acta Chir Orthop Traumatol Cech. 2022;89(2):134-138. English. PMID: 35621404.

19. Chiu CH, Chen P, Chen AC, Hsu KY, Chang SS, Chan YS, Chen YJ. Shoulder ultrasonography performed by orthopedic surgeons increases efficiency in diagnosis of rotator cuff tears. J Orthop Surg Res. 2017 Apr 20;12(1):63. doi: 10.1186/s13018-017-0565-4. PMID: 28427416; PMCID: PMC5399436.

20. Johnson SE, Kruse RC, Boettcher BJ. The Role of Ultrasound in the Diagnosis and Treatment of Meniscal Injuries. Curr Rev Musculoskelet Med. 2024 Jun;17(6):171-184. doi: 10.1007/s12178-024-09894-y. Epub 2024 Apr 19. PMID: 38639869; PMCID: PMC11091008.

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Published

2025-01-21

How to Cite

1.
TRESTKA, Gabriela, DOMINO, Wiktoria, ZELIK, Urszula, PRZYGODA, Maria, ŚNIEŻNA, Joanna, STĘPIEŃ, Kamila, ADAMCZYK, Sabina, FLORCZAK, Wojciech, WŁODYKA, Jagienka, DZIEWIC, Jakub and DZWONNIK, Karol. Imaging Diagnostics, Biomarkers, and Emerging Trends in Orthopedic Research and Treatment. Quality in Sport. Online. 21 January 2025. Vol. 37, p. 57103. [Accessed 24 June 2025]. DOI 10.12775/QS.2025.37.57103.
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Vol. 37 (2025)

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Medical Sciences

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Copyright (c) 2025 Gabriela Trestka, Wiktoria Domino, Urszula Zelik, Maria Przygoda, Joanna Śnieżna, Kamila Stępień, Sabina Adamczyk, Wojciech Florczak, Jagienka Włodyka, Jakub Dziewic, Karol Dzwonnik

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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