Air pollution and skin aging

Abstract

Air pollution is a leading environmental health risk worldwide, with detrimental effects not only on human health but also on skin aging. This review explores the link between air pollution and skin aging, focusing on the harmful effects of particulate matter (PM) and other pollutants such as polycyclic aromatic hydrocarbons (PAHs), nitrogen oxides (NO2), and ozone (O3). These pollutants penetrate the skin, inducing oxidative stress and inflammation, which accelerates the degradation of collagen and elastin in the extracellular matrix. This contributes to premature aging, wrinkles, hyperpigmentation, and inflammatory skin conditions. The smallest fractions of PM, particularly PM2.5, are the most harmful, causing significant cellular damage. Long-term exposure to these pollutants also disrupts the skin's microbiome, leading to dysbiosis and further weakening the skin's protective barrier. Current therapeutic strategies focus on protecting the skin using antioxidants, such as Vitamin C and Vitamin E, as well as probiotics and moisturizers that support the skin's natural defenses. Sunscreens also play a vital role in protecting the skin from UV-induced oxidative stress, further mitigating pollution-related damage. This review highlights the importance of developing comprehensive skincare regimens that target both pollution-induced oxidative stress and the maintenance of a healthy skin barrier. It also emphasizes the need for further research into personalized approaches to counteract the aging effects of air pollution on the skin.