Application of irreversible electroporation ablation in oncology - a narrative review
DOI:
https://doi.org/10.12775/QS.2024.29.55489Keywords
Irreversible electroporation-IRE, literature review, prostate cancer (PCa), Perihinal bile tract cancer, Pancreatic cancer, Kidney tumors, Liver cancer, Glioblastoma multiformeAbstract
Irreversible electroporation-IRE is an innovative cancer treatment method that can selectively destroy cancer cells without damaging surrounding tissues. It is a safe and effective alternative to traditional methods, with the patient faster recover potential and spare critical body structures such as blood vessels and nerves.In surgical oncology, the IRE treatment technique is used especially in cases where other methods are not possible or have limited effectiveness. The method is proving to be seen as an effective local treatment with good clinical results and limited side effects in prostate, biliary, pancreatic, kidney and liver cancers.
References
Simioni A, Valpione S, Granziera E, Rossi CR, Cavallin F, Spina R, Sieni E, Aliberti C, Stramare R, Campana LG (2020). Ablation of soft tissue tumours by long needle variable electrode-geometry electrochemotherapy: final report from a single-arm, single-centre phase-2 study. Sci Rep.;10(1):2291. https://doi.org/10.1038/s41598-020-59230-w
Wang H, Xue W, Yan W, Yin L, Dong B, He B, Yu Y, Shi W, Zhou Z, Lin H, Zhou Y, Wang Y, Shi Z, Ren S, Gao X, Wang L, Xu C. (2020). Extended Focal Ablation of Localized Prostate Cancer With High-Frequency Irreversible Electroporation: A Nonrandomized Controlled Trial. JAMA Surg.;157(8):693-700. https://doi.org/10.1001/jamasurg.2022.2230
Reddy VY, Dukkipati SR, Neuzil P, Anic A, Petru J, Funasako M, Cochet H, Minami K, Breskovic T, Sikiric I, Sediva L, Chovanec M, Koruth J, Jais P. (2021). Pulsed Field Ablation of Paroxysmal Atrial Fibrillation: 1-Year Outcomes of IMPULSE, PEFCAT, and PEFCAT II. JACC Clin Electrophysiol;7(5):614-627. https://doi.org/10.1016/j.jacep.2021.02.014
Buijs M, de Bruin DM, Wagstaff PG, J Zondervan P, Scheltema MJ, W Engelbrecht M, P Laguna M, van Lienden KP.(2021). MRI and CT in the follow-up after irreversible electroporation of small renal masses. Diagn Interv Radiol.;27(5):654-663. https://doi.org/10.5152/dir.2021.19575
Dong S, Wang H, Zhao Y, Sun Y, Yao C. (2018) First Human Trial of High-Frequency Irreversible Electroporation Therapy for Prostate Cancer. Technol Cancer Res Treat.;17:1533033818789692. https://doi.org/10.1177/1533033818789692
Yang Y, Qin Z, Du D, Wu Y, Qiu S, Mu F, Xu K, Chen J. (2019) Safety and Short-Term Efficacy of Irreversible Electroporation and Allogenic Natural Killer Cell Immunotherapy Combination in the Treatment of Patients with Unresectable Primary Liver Cancer. Cardiovasc Intervent Radiol. Jan;42(1):48-59.. Cardiovasc Interwencja Radiol.;42(1):48-59. https://doi.org/10.1007/s00270-018-2069-y
Rossmeisl J.(2017) Maximizing Local Access to Therapeutic Deliveries in Glioblastoma. Part V: Clinically Relevant Model for Testing New Therapeutic Approaches. In: De Vleeschouwer S, editor. Glioblastoma. Brisbane (AU): Codon Publications; Chapter 21. PMID: 29251874.
Tasu JP, Tougeron D, Rols MP.(2022) Irreversible electroporation and electrochemotherapy in oncology: State of the art. Diagn Interv Imaging.;103(11):499-509.. https://doi.org/10.1016/j.diii.2022.09.009
Nielsen K, Scheffer HJ, Vieveen JM, van Tilborg AA, Meijer S, van Kuijk C, van den Tol MP, Meijerink MR, Bouwman RA. (2014) Anaesthetic management during open and percutaneous irreversible electroporation. Br J Anaesth.;113(6):985-92.https://doi.org/10.1093/bja/aeu256
Narayanan G.(2015) Irreversible Electroporation. Semin Intervent Radiol.;32(4):349-55 https://doi.org/10.1055/s-0035-1564706
Valerio M, Dickinson L, Ali A, Ramachadran N, Donaldson I, Mccartan N, Freeman A, Ahmed HU, Emberton M. Nanoknife (2017) Electroporation Ablation Trial: A Prospective Development Study Investigating Focal Irreversible Electroporation for Localized Prostate Cancer. J Urol.;197(3 Pt 1):647-654. https://doi.org/10.1016/j.juro.2016.09.091
Scheltema MJ, van den Bos W, de Bruin DM, Wijkstra H, Laguna MP, de Reijke TM, de la Rosette JJ.(2016) Focal vs extended ablation in localized prostate cancer with irreversible electroporation; a multi-center randomized controlled trial. BMC Cancer.;16:299. https://doi.org/10.1186/s12885-016-2332-z
Zhang K, Teoh J, Laguna P, Dominguez-Escrig J, Barret E, Ramon-Borja JC, Muir G, Bohr J, de Reijke TM, Pelechano Gómez P, Ng CF, Sanchez-Salas R, de la Rosette J.(2023) Effect of Focal vs Extended Irreversible Electroporation for the Ablation of Localized Low- or Intermediate-Risk Prostate Cancer on Early Oncological Control: A Randomized Clinical Trial. JAMA Surg.;158(4):343-349. https://doi.org/10.1001/jamasurg.2022.7516
De la Rosette J, Dominguez-Escrig J, Zhang K, Teoh J, Barret E, Ramon-Borja JC, Muir G, Bohr J, de Reijke T, Ng CF, Leung CH, Sanchez-Salas R, Laguna P.(2023) A Multicenter, Randomized, Single-blind, 2-Arm Intervention Study Evaluating the Adverse Events and Quality of Life After Irreversible Electroporation for the Ablation of Localized Low-intermediate Risk Prostate Cancer. J Urol.;209(2):347-353.https://doi.org/10.1097/JU.0000000000003051
Franken LC, van Veldhuisen E, Ruarus AH, Coelen RJS, Roos E, van Delden OM, Besselink MG, Klümpen HJ, van Lienden KP, van Gulik TM, Meijerink MR, Erdmann JI. (2022). Outcomes of Irreversible Electroporation for Perihilar Cholangiocarcinoma: A Prospective Pilot Study. J Vasc Interv Radiol.(7):805-813.e1. https://doi.org/10.1016/j.jvir.2022.03.024
Sugimoto K, Moriyasu F, Tsuchiya T, Nagakawa Y, Hosokawa Y, Saito K, Tsuchida A, Itoi T.(2018). Irreversible Electroporation for Nonthermal Tumor Ablation in Patients with Locally Advanced Pancreatic Cancer: Initial Clinical Experience in Japan. Intern Med.;57(22):3225-3231 https://doi.org/10.2169/internalmedicine.0861-18
Vroomen LGPH, Scheffer HJ, Melenhorst MCAM, de Jong MC, van den Bergh JE, van Kuijk C, van Delft F, Kazemier G, Meijerink MR. (2017). MR and CT imaging characteristics and ablation zone volumetry of locally advanced pancreatic cancer treated with irreversible electroporation. Eur Radiol.(6):2521-2531. https://doi.org/10.1007/s00330-016-4581-2
Belfiore MP, Ronza FM, Romano F, Ianniello GP, De Lucia G, Gallo C, Marsicano C, Di Gennaro TL, Belfiore G.(2015). Percutaneous CT-guided irreversible electroporation followed by chemotherapy as a novel neoadjuvant protocol in locally advanced pancreatic cancer: Our preliminary experience. Int J Surg. Suppl 1:S34-9. https://doi.org/10.1016/j.ijsu.2015.06.049
Ma YY, Leng Y, Xing YL, Li HM, Chen JB, Niu LZ.(2020). Gemcitabine plus concurrent irreversible electroporation vs gemcitabine alone for locally advanced pancreatic cancer. World J Clin Cases.;8(22):5564-5575. https://doi.org/10.12998/wjcc.v8.i22.5564
Lin M, Zhang X, Liang S, Luo H, Alnaggar M, Liu A, Yin Z, Chen J, Niu L, Jiang Y. (2020). Irreversible electroporation plus allogenic Vγ9Vδ2 T cells enhances antitumor effect for locally advanced pancreatic cancer patients. Signal Transduct Target Ther.;5(1):215. https://doi.org/10.1038/s41392-020-00260-1
Wagstaff PG, de Bruin DM, Zondervan PJ, Savci Heijink CD, Engelbrecht MR, van Delden OM, van Leeuwen TG, Wijkstra H, de la Rosette JJ, Laguna Pes MP.(2015). The efficacy and safety of irreversible electroporation for the ablation of renal masses: a prospective, human, in-vivo study protocol. BMC Cancer.;15:165. https://doi.org/10.1186/s12885-015-1189-x
Coletti L, Battaglia V, De Simone P, Turturici L, Bartolozzi C, Filipponi F. (2017)Safety and feasibility of electrochemotherapy in patients with unresectable colorectal liver metastases: A pilot study. Int J Surg.;44:26-32. https://doi.org/10.1016/j.ijsu.2017.06.033
Lorenzo MF, Arena CB, Davalos RV. (2017) Maximizing Local Access to Therapeutic Deliveries in Glioblastoma. Part III: Irreversible Electroporation and High-Frequency Irreversible Electroporation for the Eradication of Glioblastoma. In: De Vleeschouwer S, editor. Glioblastoma [Internet]. Brisbane (AU): Codon Publications. Chapter 19. PMID: 29251858.
Scheffer HJ, Vroomen LG, Nielsen K, van Tilborg AA, Comans EF, van Kuijk C, van der Meijs BB, van den Bergh J, van den Tol PM, Meijerink MR.(2015). Colorectal liver metastatic disease: efficacy of irreversible electroporation--a single-arm phase II clinical trial (COLDFIRE-2 trial). BMC Cancer.;15:772. https://doi.org/10.1186/s12885-015-1736-5
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Dawid Piecuch, Edyta Hańczyk, Weronika Sobota, Przemysław Piskorz
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Stats
Number of views and downloads: 96
Number of citations: 0
