The effect of rising e-cigarette usage among young people on public health and physical activity
DOI:
https://doi.org/10.12775/QS.2024.23.54839Keywords
e-cigarette, vaping, ENDS, addiction, youth, adolescentsAbstract
Introduction: Electronic cigarettes (e-cigarettes/ENDS) are regarded by many as a safe alternative to traditional cigarettes. This article will present a review of the current knowledge regarding the effects and impact of electronic cigarettes on health and the risk of addiction in adolescents.
Methods: We selected articles with an unlimited search period in several databases, including PubMed, Google Scholar, Web of Science and the websites of the Polish government. Only articles with free full text were included in the review. There were no restrictions based on article type.
Conclusions: The increasing consumption of e-cigarettes (ENDS) among young people in Poland is emerging as a significant public health concern. The high addictive potential of nicotine, coupled with the toxicity of aerosols and the multitude of ways in which manufacturers make their products more appealing, gives rise to the risk of an increase in future patients with impaired performance in sports, and consequently with cardiovascular and respiratory diseases, as well as the necessity to combat addiction. Reducing and preventing the use of tobacco products by children and adolescents represents one of the most significant challenges currently facing the public health sector in Poland.
References
Samet JM. Tobacco Smoking: The Leading Cause of Preventable Disease Worldwide. Thorac Surg Clin. 2013;23(2):103-112. doi:10.1016/j.thorsurg.2013.01.009
Tobacco. Accessed April 10, 2024. https://www.who.int/health-topics/tobacco
Grana R, Benowitz N, Glantz SA. Background Paper on E-cigarettes (Electronic Nicotine Delivery Systems). Published online 2013. Accessed April 11, 2024. https://escholarship.org/uc/item/13p2b72n
Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2014;23(2):133-139. doi:10.1136/tobaccocontrol-2012-050859
Goniewicz ML, Gawron M, Smith DM, Peng M, Jacob P, Benowitz NL. Exposure to Nicotine and Selected Toxicants in Cigarette Smokers Who Switched to Electronic Cigarettes: A Longitudinal Within-Subjects Observational Study. Nicotine Tob Res Off J Soc Res Nicotine Tob. 2017;19(2):160-167. doi:10.1093/ntr/ntw160
Nian Q, Hardesty JJ, Crespi E, et al. Transitions in device and liquid characteristic groupings among US adults frequently using electronic nicotine delivery systems (ENDS) over three timepoints, 2020-2021. Tob Induc Dis. 2023;21:134. doi:10.18332/tid/171354
Laverty AA, Filippidis FT, Vardavas CI. Patterns, trends and determinants of e-cigarette use in 28 European Union Member States 2014-2017. Prev Med. 2018;116:13-18. doi:10.1016/j.ypmed.2018.08.028
Sreeramareddy C, Acharya K, Manoharan A. Electronic cigarettes use and ‘dual use’ among the youth in 75 countries: estimates from Global Youth Tobacco Surveys (2014–2019). Sci Rep. 2022;12:20967. doi:10.1038/s41598-022-25594-4
Surgeon General’s Advisory on E-cigarette Use Among Youth | Smoking & Tobacco Use | CDC. December 2018. Accessed April 9, 2024. https://www.cdc.gov/tobacco/basic_information/e-cigarettes/surgeon-general-advisory/index.html
Smith DM, Gawron M, Balwicki L, Sobczak A, Matynia M, Goniewicz ML. Exclusive versus dual use of tobacco and electronic cigarettes among adolescents in Poland, 2010–2016. Addict Behav. 2019;90:341-348. doi:10.1016/j.addbeh.2018.11.035
Kaleta D, Polanska K. Trends of e-cigarettes and tobacco use among secondary and high school students from Poland over three years observation. Tob Induc Dis. 2021;19(1). doi:10.18332/tid/140961
Janik-Koncewicz K, Parascandola M, Bachand J, Zatoński M, Przewoźniak K, Zatoński W. E-cigarette use among Polish students: findings from the 2016 Poland Global Youth Tobacco Survey. J Health Inequalities. 2020;6(2):95-103. doi:10.5114/jhi.2020.103223
E-papierosy: rosnący problem zdrowia publicznego - Ministerstwo Zdrowia - Portal Gov.pl. Ministerstwo Zdrowia. Accessed April 9, 2024. https://www.gov.pl/web/zdrowie/e-papierosy-rosnacy-problem-zdrowia-publicznego
E-papierosy to plaga wśród dzieci i młodzieży. Rzeczniczka popiera ograniczanie ich sprzedaży. Rzecznik Praw Dziecka. Accessed April 9, 2024. https://brpd.gov.pl/2024/02/27/e-papierosy-to-plaga-wsrod-dzieci-i-mlodziezy-rzeczniczka-popiera-ograniczanie-ich-sprzedazy/
Alarmujące wyniki badań: e-papierosy stały się nałogiem młodzieży. Rzecznik Praw Dziecka. Accessed April 9, 2024. https://brpd.gov.pl/2020/12/28/alarmujace-wyniki-badan-e-papierosy-staly-sie-nalogiem-mlodziezy/
Leventhal AM, Madden DR, Peraza N, et al. Effect of Exposure to e-Cigarettes With Salt vs Free-Base Nicotine on the Appeal and Sensory Experience of Vaping. JAMA Netw Open. 2021;4(1):e2032757. doi:10.1001/jamanetworkopen.2020.32757
Duell AK, Pankow JF, Peyton DH. Nicotine in tobacco product aerosols: “It’s déjà vu all over again.” Tob Control. 2020;29(6):656-662. doi:10.1136/tobaccocontrol-2019-055275
Carstens E, Carstens MI. Sensory Effects of Nicotine and Tobacco. Nicotine Tob Res Off J Soc Res Nicotine Tob. 2022;24(3):306-315. doi:10.1093/ntr/ntab086
Kichko TI, Kobal G, Reeh PW. Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx. Am J Physiol Lung Cell Mol Physiol. 2015;309(8):L812-820. doi:10.1152/ajplung.00164.2015
Pullicin AJ, Kim H, Brinkman MC, Buehler SS, Clark PI, Lim J. Impacts of Nicotine and Flavoring on the Sensory Perception of E-Cigarette Aerosol. Nicotine Tob Res Off J Soc Res Nicotine Tob. 2020;22(5):806-813. doi:10.1093/ntr/ntz058
Harvanko AM, Havel CM, Jacob P, Benowitz NL. Characterization of Nicotine Salts in 23 Electronic Cigarette Refill Liquids. Nicotine Tob Res. 2019;22(7):1239-1243. doi:10.1093/ntr/ntz232
O’Connell G, Pritchard JD, Prue C, et al. A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic profiles of cigarettes and e-cigarettes with nicotine salt formulations in US adult smokers. Intern Emerg Med. 2019;14(6):853-861. doi:10.1007/s11739-019-02025-3
Willis DN, Liu B, Ha MA, Jordt SE, Morris JB. Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants. FASEB J. 2011;25(12):4434-4444. doi:10.1096/fj.11-188383
Ha MA, Smith GJ, Cichocki JA, et al. Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice. PloS One. 2015;10(2):e0117128. doi:10.1371/journal.pone.0117128
Rosbrook K, Green BG. Sensory Effects of Menthol and Nicotine in an E-Cigarette. Nicotine Tob Res Off J Soc Res Nicotine Tob. 2016;18(7):1588-1595. doi:10.1093/ntr/ntw019
Leventhal AM, Tackett AP, Whitted L, Jordt SE, Jabba SV. Ice flavours and non-menthol synthetic cooling agents in e-cigarette products: a review. Tob Control. 2023;32(6):769-777. doi:10.1136/tobaccocontrol-2021-057073
Kaplan B, Hardesty JJ, Welding K, Breland AB, Eissenberg T, Cohen JE. Electronic Nicotine Delivery System flavor use over time by age group in the US: A longitudinal analysis. Tob Induc Dis. 2023;21:67. doi:10.18332/tid/162365
Goldenson NI, Kirkpatrick MG, Barrington-Trimis JL, et al. Effects of sweet flavorings and nicotine on the appeal and sensory properties of e-cigarettes among young adult vapers: Application of a novel methodology. Drug Alcohol Depend. 2016;168:176-180. doi:10.1016/j.drugalcdep.2016.09.014
Landry RL, Groom AL, Vu THT, et al. The role of flavors in vaping initiation and satisfaction among U.S. adults. Addict Behav. 2019;99:106077. doi:10.1016/j.addbeh.2019.106077
Tsai J, Walton K, Coleman BN, et al. Reasons for Electronic Cigarette Use Among Middle and High School Students - National Youth Tobacco Survey, United States, 2016. MMWR Morb Mortal Wkly Rep. 2018;67(6):196-200. doi:10.15585/mmwr.mm6706a5
Thoonen KAHJ, Jongenelis MI. Motivators of e-cigarette use among Australian adolescents, young adults, and adults. Soc Sci Med 1982. 2024;340:116411. doi:10.1016/j.socscimed.2023.116411
Lindpere V, Winickoff JP, Khan AS, et al. Reasons for E-cigarette Use, Vaping Patterns, and Cessation Behaviors Among US Adolescents. Nicotine Tob Res Off J Soc Res Nicotine Tob. 2023;25(5):975-982. doi:10.1093/ntr/ntac278
Groom AL, Vu THT, Kesh A, et al. Correlates of youth vaping flavor preferences. Prev Med Rep. 2020;18:101094. doi:10.1016/j.pmedr.2020.101094
Wills TA, Soneji SS, Choi K, Jaspers I, Tam EK. E-cigarette use and respiratory disorders: an integrative review of converging evidence from epidemiological and laboratory studies. Eur Respir J. 2021;57(1):1901815. doi:10.1183/13993003.01815-2019
Osei AD, Mirbolouk M, Orimoloye OA, et al. Association Between E-Cigarette Use and Chronic Obstructive Pulmonary Disease by Smoking Status: Behavioral Risk Factor Surveillance System 2016 and 2017. Am J Prev Med. 2020;58(3):336-342. doi:10.1016/j.amepre.2019.10.014
Scheffler S, Dieken H, Krischenowski O, Förster C, Branscheid D, Aufderheide M. Evaluation of E-cigarette liquid vapor and mainstream cigarette smoke after direct exposure of primary human bronchial epithelial cells. Int J Environ Res Public Health. 2015;12(4):3915-3925. doi:10.3390/ijerph120403915
Anderson C, Majeste A, Hanus J, Wang S. E-Cigarette Aerosol Exposure Induces Reactive Oxygen Species, DNA Damage, and Cell Death in Vascular Endothelial Cells. Toxicol Sci Off J Soc Toxicol. 2016;154(2):332-340. doi:10.1093/toxsci/kfw166
Crotty Alexander LE, Drummond CA, Hepokoski M, et al. Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice. Am J Physiol Regul Integr Comp Physiol. 2018;314(6):R834-R847. doi:10.1152/ajpregu.00270.2017
Hua M, Omaiye EE, Luo W, McWhirter KJ, Pankow JF, Talbot P. Identification of Cytotoxic Flavor Chemicals in Top-Selling Electronic Cigarette Refill Fluids. Sci Rep. 2019;9(1):2782. doi:10.1038/s41598-019-38978-w
Muthumalage T, Prinz M, Ansah KO, Gerloff J, Sundar IK, Rahman I. Inflammatory and Oxidative Responses Induced by Exposure to Commonly Used e-Cigarette Flavoring Chemicals and Flavored e-Liquids without Nicotine. Front Physiol. 2017;8:1130. doi:10.3389/fphys.2017.01130
Leigh NJ, Lawton RI, Hershberger PA, Goniewicz ML. Flavourings significantly affect inhalation toxicity of aerosol generated from electronic nicotine delivery systems (ENDS). Tob Control. 2016;25(Suppl 2):ii81-ii87. doi:10.1136/tobaccocontrol-2016-053205
Clapp PW, Pawlak EA, Lackey JT, et al. Flavored e-cigarette liquids and cinnamaldehyde impair respiratory innate immune cell function. Am J Physiol-Lung Cell Mol Physiol. 2017;313(2):L278-L292. doi:10.1152/ajplung.00452.2016
Hutzler C, Paschke M, Kruschinski S, Henkler F, Hahn J, Luch A. Chemical hazards present in liquids and vapors of electronic cigarettes. Arch Toxicol. 2014;88(7):1295-1308. doi:10.1007/s00204-014-1294-7
Escobar YNH, Nipp G, Cui T, Petters SS, Surratt JD, Jaspers I. In Vitro Toxicity and Chemical Characterization of Aerosol Derived from Electronic Cigarette Humectants Using a Newly Developed Exposure System. Chem Res Toxicol. 2020;33(7):1677-1688. doi:10.1021/acs.chemrestox.9b00490
Kim MD, Chung S, Baumlin N, et al. The combination of propylene glycol and vegetable glycerin e-cigarette aerosols induces airway inflammation and mucus hyperconcentration. Sci Rep. 2024;14(1):1942. doi:10.1038/s41598-024-52317-8
Kim MD, Chung S, Dennis JS, et al. Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction. Front Pharmacol. 2022;13:1012723. doi:10.3389/fphar.2022.1012723
Kim MD, Chung S, Baumlin N, et al. E-cigarette aerosols of propylene glycol impair BK channel activity and parameters of mucociliary function. Am J Physiol Lung Cell Mol Physiol. 2023;324(4):L468-L479. doi:10.1152/ajplung.00157.2022
Saliba NA, El Hellani A, Honein E, et al. Surface chemistry of electronic cigarette electrical heating coils: Effects of metal type on propylene glycol thermal decomposition. J Anal Appl Pyrolysis. 2018;134:520-525. doi:10.1016/j.jaap.2018.07.019
Woodall M, Jacob J, Kalsi KK, et al. E-cigarette constituents propylene glycol and vegetable glycerin decrease glucose uptake and its metabolism in airway epithelial cells in vitro. Am J Physiol Lung Cell Mol Physiol. 2020;319(6):L957-L967. doi:10.1152/ajplung.00123.2020
Hwang JH, Lyes M, Sladewski K, et al. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med Berl Ger. 2016;94(6):667-679. doi:10.1007/s00109-016-1378-3
Madison MC, Landers CT, Gu BH, et al. Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine. J Clin Invest. 2019;129(10):4290-4304. doi:10.1172/JCI128531
Larue F, Tasbih T, Ribeiro PAB, Lavoie KL, Dolan E, Bacon SL. Immediate physiological effects of acute electronic cigarette use in humans: A systematic review and meta-analysis. Respir Med. 2021;190. doi:10.1016/j.rmed.2021.106684
Moshensky A, Brand CS, Alhaddad H, et al. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice. eLife. 2022;11:e67621. doi:10.7554/eLife.67621
Salzman GA, Alqawasma M, Asad H. Vaping Associated Lung Injury (EVALI): An Explosive United States Epidemic. Mo Med. 2019;116(6):492-496.
Marrocco A, Singh D, Christiani DC, Demokritou P. E-Cigarette Vaping Associated Acute Lung Injury (EVALI): State of science and future research needs. Crit Rev Toxicol. 2022;52(3):188-220. doi:10.1080/10408444.2022.2082918
Moritz ED, Zapata LB, Lekiachvili A, et al. Update: Characteristics of Patients in a National Outbreak of E-cigarette, or Vaping, Product Use-Associated Lung Injuries - United States, October 2019. MMWR Morb Mortal Wkly Rep. 2019;68(43):985-989. doi:10.15585/mmwr.mm6843e1
Giroud C, de Cesare M, Berthet A, Varlet V, Concha-Lozano N, Favrat B. E-Cigarettes: A Review of New Trends in Cannabis Use. Int J Environ Res Public Health. 2015;12(8):9988-10008. doi:10.3390/ijerph120809988
Carlos WG, Crotty Alexander LE, Gross JE, et al. Vaping-associated Pulmonary Illness (VAPI). Am J Respir Crit Care Med. 2019;200(7):P13-P14. doi:10.1164/rccm.2007P13
Hayes D, Board A, Calfee CS, et al. Pulmonary and Critical Care Considerations for e-Cigarette, or Vaping, Product Use-Associated Lung Injury. Chest. 2022;162(1):256-264. doi:10.1016/j.chest.2022.02.039
Lee H. Vitamin E acetate as linactant in the pathophysiology of EVALI. Med Hypotheses. 2020;144:110182. doi:10.1016/j.mehy.2020.110182
Pokhrel P, Schmid S, Pagano I. Physical Activity and Use of Cigarettes and E-Cigarettes Among Young Adults. Am J Prev Med. 2020;58(4):580-583. doi:10.1016/j.amepre.2019.10.015
Dinkeloo E, Grier TL, Brooks RD, Jones BH. Vaping, Smoking, and the Physical Fitness of Active Young Men. Am J Prev Med. 2020;58(1):e31-e37. doi:10.1016/j.amepre.2019.08.015
Jankowski M, Krzystanek M, Zejda JE, et al. E-Cigarettes are More Addictive than Traditional Cigarettes-A Study in Highly Educated Young People. Int J Environ Res Public Health. 2019;16(13):2279. doi:10.3390/ijerph16132279
Keller-Hamilton B, Lu B, Roberts ME, Berman ML, Root ED, Ferketich AK. Electronic cigarette use and risk of cigarette and smokeless tobacco initiation among adolescent boys: A propensity score matched analysis. Addict Behav. 2021;114:106770. doi:10.1016/j.addbeh.2020.106770
Loukas A, Marti CN, Cooper M, Pasch KE, Perry CL. Exclusive e-cigarette use predicts cigarette initiation among college students. Addict Behav. 2018;76:343-347. doi:10.1016/j.addbeh.2017.08.023
Berry KM, Fetterman JL, Benjamin EJ, et al. Association of Electronic Cigarette Use With Subsequent Initiation of Tobacco Cigarettes in US Youths. JAMA Netw Open. 2019;2(2):e187794. doi:10.1001/jamanetworkopen.2018.7794
Soneji S, Barrington-Trimis JL, Wills TA, et al. Association Between Initial Use of e-Cigarettes and Subsequent Cigarette Smoking Among Adolescents and Young Adults. JAMA Pediatr. 2017;171(8):788-797. doi:10.1001/jamapediatrics.2017.1488
Baenziger ON, Ford L, Yazidjoglou A, Joshy G, Banks E. E-cigarette use and combustible tobacco cigarette smoking uptake among non-smokers, including relapse in former smokers: umbrella review, systematic review and meta-analysis. BMJ Open. 2021;11(3):e045603. doi:10.1136/bmjopen-2020-045603
Kong G, Chaffee BW, Wu R, et al. E-cigarette device type and combustible tobacco use: Results from a pooled analysis of 10,482 youth. Drug Alcohol Depend. 2022;232:109279. doi:10.1016/j.drugalcdep.2022.109279
Yoong SL, Hall A, Turon H, et al. Association between electronic nicotine delivery systems and electronic non-nicotine delivery systems with initiation of tobacco use in individuals aged < 20 years. A systematic review and meta-analysis. PloS One. 2021;16(9):e0256044. doi:10.1371/journal.pone.0256044
O’Brien D, Long J, Quigley J, Lee C, McCarthy A, Kavanagh P. Association between electronic cigarette use and tobacco cigarette smoking initiation in adolescents: a systematic review and meta-analysis. BMC Public Health. 2021;21(1):954. doi:10.1186/s12889-021-10935-1
Purba AK, Thomson RM, Henery PM, Pearce A, Henderson M, Katikireddi SV. Social media use and health risk behaviours in young people: systematic review and meta-analysis. BMJ. 2023;383:e073552. doi:10.1136/bmj-2022-073552
Lau L, Conti AA, Hemmati Z, Baldacchino A. The prospective association between the use of E-cigarettes and other psychoactive substances in young people: A systematic review and meta-analysis. Neurosci Biobehav Rev. 2023;153:105392. doi:10.1016/j.neubiorev.2023.105392
Hershberger A, Argyriou E, Cyders M. Electronic nicotine delivery system use is related to higher odds of alcohol and marijuana use in adolescents: Meta-analytic evidence. Addict Behav. 2020;105:106325. doi:10.1016/j.addbeh.2020.106325
Vasiljevic M, St John Wallis A, Codling S, Couturier DL, Sutton S, Marteau TM. E-cigarette adverts and children’s perceptions of tobacco smoking harms: an experimental study and meta-analysis. BMJ Open. 2018;8(7):e020247. doi:10.1136/bmjopen-2017-020247
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Copyright (c) 2024 Mariusz Krompiewski, Marek Miśkiewicz, Jakub Ptak, Rafał Noga, Jagoda Marcinkowska, Adrian Herc, Karolina Koczkodon, Victoria Teska, Jakub Perłowski, Marcelina Sawczuk
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