Schamberg's Disease: A Comprehensive Review
DOI:
https://doi.org/10.12775/QS.2024.23.54739Keywords
Schamberg's disease, etiology, diagnosis, treatmentAbstract
Schamberg's disease, also known as progressive pigmented vasculitis, is a rare, chronic skin disorder characterized by petechiae and brown spots, mainly on the lower extremities. In this review article, we provide a detailed overview of Schamberg's disease. We review its causes, pathogenesis, and histopathological features. We also describe the clinical presentation, diagnostic methods, and treatment options. We emphasize the crucial role of a multidisciplinary approach in the treatment of this condition. We also emphasize the need for further research to better understand the mechanisms underlying Schamberg's disease. This could lead to the development of more targeted therapies in the future.
References
Zvulunov A, Avinoach I, Hatskelzon L, Halevy S. Pigmented purpuric dermatosis (Schamberg's purpura) in an infant. Dermatol Online J. 1999 May;5(1):2.
Sardana K, Sarkar R, Sehgal VN. Pigmented purpuric dermatoses: an overview. Int J Dermatol. 2004;43(7):482-488.
Dowd PM, Champion RH, Purpura. In: RH Champion, J L Burton, DA Burns, SM Breathnach, eds Textbook of Dermatology, 6th edn. Vol. 3. Oxford: Blackwell Scientific Publications, 1998: 2141–2154.
Gönül M, Külcü Çakmak S, Ozcan N, Oğuz ID, Gül Ü, Bıyıklı Z. Clinical and laboratory findings of pigmented purpuric dermatoses. Ann Dermatol. 2014;26(5):610-614.
Ehsani AH, Ghodsi SZ, Nourmohammadpour P, Aghazadeh N, Damavandi MR. Pigmented purpura dermatosis and viral hepatitis: a case-control study. Australas J Dermatol. 2013;54(3):225-227.
Taketuchi Y, Chinen T, Ichikawa Y, Ito M. Two cases of unilateral pigmented purpuric dermatosis. J Dermatol. 2001;28(9):493-498.
Saito R, Matsuoka Y. Granulomatous pigmented purpuric dermatosis. J Dermatol 1996; 23: 551–555.
Dessoukey MW, Abdel-Dayem H, Omar MF, Al-Suweidi NE. Pigmented purpuric dermatosis and hepatitis profile: a report on 10 patients. Int J Dermatol. 2005;44(6):486-488.
Filo V, Galbavy S, Fiolva A, et al. Unilateral progressive pigmentary capillaropathy (Schambergs’ disease?) of the arm. Br J Dermatol 2001; 144: 190–191.
Ratnam KV, Su WP, Peters MS. Purpura simplex (inflammatory purpura without vasculitis): a clinicopathologic study of 174 cases. J Am Acad Dermatol. 1991;25(4):642-647.
Ghersetich I, Lotti T, Bacci S, Comacchi C, Campanile G, Romagnoli P. Cell infiltrate in progressive pigmented purpura (Schamberg's disease): immunophenotype, adhesion receptors, and intercellular relationships. Int J Dermatol. 1995;34(12):846-850.
Torrelo A, Requena C, Mediero IG, Zambrano A. Schamberg's purpura in children: a review of 13 cases. J Am Acad Dermatol. 2003;48(1):31-33.
Kwon SJ, Lee CW. Figurate purpuric eruptions on the trunk: acetaminophen-induced rashes. J Dermatol 1998; 25: 756–758.
Hersh CS, Shwayder TA. Unilateral progressive pigmentary purpura (Schamberg's disease) in a 15-year-old boy. J Am Acad Dermatol. 1991;24(4):651.
Smoller BR, Kamel OW. Pigmented purpuric eruptions: immunopathologic studies supportive of a common immunophenotype. J Cutan Pathol. 1991;18(6):423-427.
Kim DH, Seo SH, Ahn HH, Kye YC, Choi JE. Characteristics and clinical manifestations of pigmented purpuric dermatosis. Ann Dermatol. 2015;27(4):404-410.
Sharma L, Gupta S. Clinicoepidemiological study of pigmented purpuric dermatoses. Indian Dermatol Online J. 2012;3(1):17-20.
Wong WK, Ratnam KV. A report of two cases of pigmented purpuric dermatoses treated with PUVA therapy. Acta Derm Venereol 1991; 71: 68–70.
Tristani-Firouzi P, Meadows KP, Vanderhooft S. Pigmented purpuric eruptions of childhood: a series of cases and review of literature. Pediatr Dermatol. 2001;18(4):299-304.
Brauer JA, Mundi J, Chu J, Patel R, Meehan S, Greenspan AH, Stein J. Progressive pigmentary purpura. Dermatol Online J. 2011 Oct 15;17(10):14.
Nishioka K, Katayama I, Masuzawa M, Yokozeki H, Nishiyama S. Drug-induced chronic pigmented purpura. J Dermatol. 1989;16(3):220-222.
Reinhold U, Seiter S, Ugurel S, Tilgen W. Treatment of progressive pigmented purpura with oral bioflavonoids and ascorbic acid: an open pilot study in 3 patients. J Am Acad Dermatol. 1999;41(2 Pt 1):207-208.
Krizsa J, Hunyadi J, Dobozy A. PUVA treatment of pigmented purpuric lichenoid dermatitis (Gougerot-Blum). J Am Acad Dermatol. 1992;27(5 Pt 1):778-780.
Mun JH, Jwa SW, Song M, et al. Extensive pigmented purpuric dermatosis successfully treated with pentoxifylline. Ann Dermatol. 2011;23(Suppl 3):S305-S307.
Okada K, Ishikawa O, Miyachi Y. Purpura pigmentosa chronica successfully treated with oral cyclosporin A. Br J Dermatol. 1996;134(1):180-181.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Anna Mataczyńska, Michał Paprocki, Mateusz Dobosz, Klaudia Arciszewska, Aleksandra Padkowska, Jakub Maciej Pieniążek, Justyna Skibińska, Anna Szpernalowska
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Stats
Number of views and downloads: 77
Number of citations: 0
