The influence of selected plant stimulants and mushrooms on the human body
DOI:
https://doi.org/10.12775/QS.2024.21.54217Keywords
herbs stimulants, fungi, side effects, adaptogens, advantagesAbstract
INTRODUCTION
In recent years, there has been an increase in the use of herbal stimulants around the world. Many people cannot imagine life without coffee, a cup of this drink is often a mandatory part of the day. As the world moves faster and faster, people are looking for a way to keep up with it. Therefore, more and more plant and mushroom stimulants appear on the market, which help people replenish energy deficiencies and meet the challenge of constantly living on the run. Selected stimulants, the benefits associated with their use, and side effects are described in the work below.
THE AIM
The aim of this work is to discuss the properties that stimulate the human body. We have selected less and more known plants and mushrooms, describing their properties, benefits of their use, side effects, and contraindications to their use.
MATERIALS AND METHODS
In this work, we describe the impact of substances that stimulate the human body contained in selected plants and mushrooms. A review of the literature available in the National Library of Medicine database at https://pubmed.ncbi.nlm.nih.gov and Google Scholar was conducted. The articles were searched using keywords such as herbs stimulants, fungi, side effects, adaptogens, and advantages.
SUMMARY
There are many plants and fungi in nature containing substances that have a beneficial effect on the human body. They improve brain function, reduce stress, and increase concentration. We often reach for them because we really need an additional energy booster in today's world. However, it should be remembered that these agents in too high doses may also cause side effects. Therefore, these preparations should be selected individually, taking into account chronic diseases, conditions such as pregnancy and lactation, and medications taken.
References
Evans J, Richards JR, Battisti AS. Caffeine. 2024 May 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 30137774. Available online: https://www.ncbi.nlm.nih.gov/books/NBK519490/ Access 03.08.2024.
Willson C. The clinical toxicology of caffeine: A review and case study. Toxicology Reports 2018; 5: 1140–1152. doi: 10.1016/j.toxrep.2018.11.002.
Andrews KW, Schweitzer A, Zhao C et al.The caffeine contents of dietary supplements commonly purchased in the US: analysis of 53 products with caffeine – contsining ingredients. Anal Bioanal Chem.2007; 398 (1): 231–239. doi:10.1007/s00216-007-1437-2.
Lamer-Zarawska E, Kowal-Gierczak B, Niedworok J. Phytotherapy and plant medicines. Warsaw: PZWL; 2007: 214–216.
Balawejder-Biśto A, Pyka-Pająk A.Caffeine – a substance known or learned. Farm Pol, 2022, 78.8: 430-441.
Ferré S. An update on the mechanisms of the psychostimulant effects of caffeine. J Neurochem. 2008 May;105(4):1067-79.
Fisone G, Borgkvist A, Usiello A. Caffeine as a psychomotor stimulant: mechanism of action. Cell Mol Life Sci. 2004 Apr;61(7-8):857-72.
Stough C, Clarke J, Lloyd J, Nathan PJ. Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants. Int J Neuropsychopharmacol. 2001 Jun;4(2):131-4. doi: 10.1017/S1461145701002292. PMID: 11466162.
Boekema PJ, Samsom M, van Berge Henegouwen GP, Smout AJ. Coffee and gastrointestinal function: facts and fiction. A review. Scand J Gastroenterol Suppl. 1999;230:35-9.
Poole R, Kennedy OJ, Roderick P, Fallowfield JA, Hayes PC, Parkes J. Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes. BMJ 2017; 359(11). doi: 10.1136/bmj.j5024.
Li ZD, Geng MY, Dou SR, Wang X, Zhang ZH, Chang YZ. Caffeine decreases hepcidin expression to alleviate aberrant iron metabolism under inflammation by regulating the IL-6/STAT3 pathway. Life 2022; 12(7). doi: 10.3390/life12071025.
Yelanchezian YM, Waldvogel HJ, Faull RLM, Kwakowsky A. Neuroprotective effect of caffeine in Alzheimer’s disease. Molecules 2022; 27(12). doi: 10.3390/molecules27123737.
Synnes A, Grunau RE. Neurodevelopmental outcomes after neonatal caffeine therapy. Seminars in Featal and Neonatal Medicine 2020; 25(6). doi: 10.1016/j.siny.2020.101160.
. Berman NK, Honig S, Cronstein BN, Pillinger MH. The effects of caffeine on bone mineral density and fracture risk. Osteoporos Int 2022; 33: 1235–1241. doi:10.1007/s00198-021-05972-w.
Juliano LM, Griffiths RR. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features. Psychopharmacology (Berl). 2004 Oct;176(1):1-29
Cox C, Hashem NG, Tebbs J, Bookstaver PB, Iskersky V. Evaluation of caffeine and the development of necrotizing enterocolitis. J Neonatal Perinatal Med. 2015;8(4):339-47.
Peres Natália da Silva Leitão et al. Medicinal effects of Peruvian maca (Lepidium meyenii): A review. Food & function, 2020, 11.1: 83-92.
Gonzales GF. Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands. Evid Based Complement Alternat Med. 2012;2012:193496. doi: 10.1155/2012/193496. Epub 2011 Oct 2. PMID: 21977053; PMCID: PMC3184420.
A.S. Marchev et al., Rhodiola rosea L.: from golden root to green cell factories, Phytochem. Rev. 15 (4) (2016) 515–536.
Panossian A, Wikman G, Sarris J, Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy, Phytomedicine 17 (7) (2010) 481–493.
PTL, Postgraduate School of Aesthetic Medicine. Adaptogens correcting the body's response to stress and homeostatic disorders-helping to prevent diseases of civilisation.
Pu Wei-ling et al. Anti-inflammatory effects of Rhodiola rosea L.: A review. Biomedicine & Pharmacotherapy, 2020, 121: 109552.
Wang H, Yang S, Yang X, Effect and mechanism of sofren injection in the treatment of stable angina petoris, Inf. Trad. Chinese Med. 34 (6) (2017) 56–60.
Yuan L, Li X, Evaluation on the effect of rhodiola sachalinensis on the improvement of early diabetic nephropathy, Chinese Community Doctors 34 (5) (2018)103–104.
Winston D, RH (AHG), Maimes S. Adaptogens. Herbs for Strehgth, Stamina and Stress relief. Healing Arts Press, Rochester, Vermont. 2007
Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022. PMID: 23439798; PMCID: PMC3573577.
Fluyau D, Revadigar N. Biochemical benefits, diagnosis, and clinical risks evaluation of kratom. Frontiers in psychiatry, 2017, 8: 62.
Chan KB, Pakiam C, Rahim RA. Psychoactive plant abuse: the identification of mitragynine in ketum and in ketum preparations. Bull Narc (2005) 57(1–2):249–56.
Hassan Z, Muzaimi M, Navaratnam V et al. From kratom to mitragynine and its derivatives: physiological and behavioral effects related to use, abuse, and addiction. Neurosci Biobehav Rev (2013) 37:138–51. doi:10.1016/j.neubiorev.2012.11.012
Shaik Mossadeq WM, Sulaiman MR, Tengku Mohamad TA et al. Anti-inflammatory and antinociceptive effects of Mitragyna speciosa Korth methanolic extract. Med Princ Pract (2009)18:378–84.doi:10.1159/000226292
Drug Enforcement Administration Office of Diversion Control Drug & Chemical Evaluation Section. KRATOM (Mitragyna speciosa Korth) (Street Names: Thang, Kakuam, Thom, Ketum, Biak). (2013)
Suwanlert S . A study of kratom eaters in Thailand. Bull Narc.1975;27(3):21-27.
Prozialeck, Walter C, Jateen K Jivan, Shridhar V Andurkar. "Pharmacology of kratom: an emerging botanical agent with stimulant, analgesic and opioid-like effects." Journal of Osteopathic Medicine 112.12 (2012): 792-799.Malík
Malík M, Tlustoš P. Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers. Plants (Basel). 2023 Mar 18;12(6):1364. doi: 10.3390/plants12061364. PMID: 36987052; PMCID: PMC10056569.
Cooley K, Szczurko O, Perri D et al. Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974. PLoS One. 2009 Aug 31;4(8):e6628. doi: 10.1371/journal.pone.0006628. PMID: 19718255; PMCID: PMC2729375.
Biswajit Auddy et al.: A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study. JANA. 2008, 11(1), 51-57.
Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013 Jul;12(4):312-22. doi: 10.1177/1534735412464551. Epub 2012 Nov 9. PMID: 23142798.
Garcia JF, Arribalzaga S, Díez R et al. Herbs as an Active Ingredient in Sport: Availability and Information on the Internet. Nutrients. 2022 Jul 4;14(13):2764. doi: 10.3390/nu14132764. PMID: 35807943; PMCID: PMC9268717.
Sellami M, Slimeni O, Pokrywka A et al. Herbal medicine for sports: A review. J. Int. Soc. Sports Nutr. 2018;15:14. doi: 10.1186/s12970-018-0218-y
Tarasiuk A ,Plant extracts (extract, DER, standardisation), www.labor.com.pl, Access 11.08.2024.
Lovett-Doust J.Plant strategies, vegetation processes, and ecosystem properties, 2002.
Grodzka A, Kużaj W, Zielińska-Pisklak M, Szeleszczuk Ł, Sobczak M . CAFFEINE AND OTHER PHARMACOLOGICALLY ACTIVE INGREDIENTS CONTAINED IN COFFEE BEANS. (2021) Prospects in Pharmaceutical Sciences, 19(1), 1–8. https://doi.org/10.56782/pps.11
Heck C I, De Mejia E G . Yerba Mate Tea (Ilex paraguariensis): a comprehensive review on chemistry, health implications, and technological considerations. (2007) Journal of food science, 72(9), R138-R151.
Liu Y, Guo ZJ, Zhou XW. Chinese Cordyceps: Bioactive Components, Antitumor Effects and Underlying Mechanism-A Review. Molecules. 2022 Oct 4;27(19):6576. doi: 10.3390/molecules27196576. PMID: 36235111; PMCID: PMC9572669.
Ashraf SA, Elkhalifa AEO, Siddiqui AJ et al. Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic Potential. Molecules. 2020 Jun 12;25(12):2735. doi: 10.3390/molecules25122735. PMID: 32545666; PMCID: PMC7356751.
Docherty S, Doughty FL, Smith EF. The Acute and Chronic Effects of Lion's Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study. Nutrients. 2023 Nov 20;15(22):4842. doi: 10.3390/nu15224842. PMID: 38004235; PMCID: PMC10675414.
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. Lion’s Mane. 2024 Jan 5. PMID: 38289992.
Sharma AK, Basu I, Singh S. Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial. J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. Epub 2017 Aug 22. PMID: 28829155.
Chong PS, Fung ML, Wong KH, Lim LW. Therapeutic Potential of Hericium erinaceus for Depressive Disorder. Int J Mol Sci. 2019 Dec 25;21(1):163. doi: 10.3390/ijms21010163. PMID: 31881712; PMCID: PMC6982118.
Hack B, Penna EM, Talik T, Chandrashekhar R, Millard-Stafford M. Effect of Guarana (Paullinia cupana) on Cognitive Performance: A Systematic Review and Meta-Analysis. Nutrients. 2023 Jan 14;15(2):434. doi: 10.3390/nu15020434. PMID: 36678305; PMCID: PMC9865053.
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Copyright (c) 2024 Marta Wojaczek, Katarzyna Polańska, Weronika Kahan, Dominika Poborowska, Weronika Szafrańska, Magdalena Kras, Agnieszka Kosińska, Piotr Niedbał, Katarzyna Lelek, Marcin Łata
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