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Quality in Sport

Complex minoxidil and platelet-rich plasma therapy effectiveness and its impact on physical performance
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  4. Medical Sciences

Complex minoxidil and platelet-rich plasma therapy effectiveness and its impact on physical performance

Authors

  • Paulina Cuper Brothers Hospitallers of Saint John of God Hospital in Cracow; Trynitarska 11 Street, 31-061 Kraków, Poland https://orcid.org/0009-0007-5386-4338
  • Piotr Pawłucki Department of Diagnostic Medicine, John Paul 2nd Hospital, Prądnicka 80, 31-202, Kraków, Poland https://orcid.org/0009-0008-9600-2049
  • Anna Maciak 5th The Military Clinical Hospital with Polyclinic in Cracow, Wrocławska 1/3, 30-901 Kraków, Poland https://orcid.org/0009-0004-4227-6168
  • Michał Andrzej Kozicz Brothers Hospitallers Hospital in Kraków, Trynitarska 11, 31-061 Kraków, Poland https://orcid.org/0009-0001-4254-4087
  • Ilona Jastrzębska Grochowski Hospital, Grenadierow 51/59, 04-073 Warsaw, Poland https://orcid.org/0000-0001-6754-529X
  • Krzysztof Bilecki SP ZOZ MSWiA, Kronikarza Galla 25, 30-053 Cracow, Poland https://orcid.org/0009-0001-8778-1422
  • Hubert Gugulski Jagiellonian University Medical College, św Anny 12, 31-008 Kraków, Poland https://orcid.org/0009-0004-1294-9835
  • Michał Bado The University Hospital in Krakow, Jakubowskiego 2, 30-688 Krakow, Poland https://orcid.org/0009-0008-6595-6560
  • Patrycja Nowoświat The University Hospital in Krakow, Jakubowskiego 2, 30-688 Krakow, Poland https://orcid.org/0009-0008-7939-6621
  • Michał Sekuła Chair and Department of Neurology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, Poland https://orcid.org/0000-0001-8378-9964

DOI:

https://doi.org/10.12775/QS.2024.19.53183

Keywords

minoxidil, platelet-rich plasma, androgenetic alopecia, monotherapy, combined therapy, review

Abstract

Background

Minoxidil and platelet-rich plasma (PRP) are proven treatments for androgenetic alopecia, however their combined therapy is not as researched.

Research materials and methods

Materials used for our research consist of published papers that pertain to both minoxidil and platelet-rich plasma therapies. More comprehensive papers, such as those including other substances were also included although results about other substances were not included, we simply discarded them. Each of the found and chosen articles were added and processed by various formulas which aim were to calculate efficacy of combined therapy while minimizing the errors and biases that could prop up in the source papers. Overall goal was to consolidate knowledge of the efficacy of combined therapy of minoxidil and platelet-rich plasma with emphasis on effect that could affect the physical performance.

Results

All trials have shown statistically significant improvement when compared to minoxidil monotherapy. Compared to PRP monotherapy results had been superior although not always in statistically significant manner. No trials have shown additional, adverse interactions, side effects or impacts on physical performance beyond those expected from the monotherapies, proving combined is as safe as monotherapies.

Conclusion

Combined therapy is proven to yield better results, while remaining a safe and cost-effective method. It doesn’t impact physical performance in any way if taken correctly. Still higher quantity of research is welcome to make those finding more stable and in order to better assess the positive effect of combing titular substances.

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Published

2024-07-28

How to Cite

1.
CUPER, Paulina, PAWŁUCKI, Piotr, MACIAK, Anna, KOZICZ, Michał Andrzej, JASTRZĘBSKA, Ilona, BILECKI, Krzysztof, GUGULSKI, Hubert, BADO, Michał, NOWOŚWIAT, Patrycja and SEKUŁA, Michał. Complex minoxidil and platelet-rich plasma therapy effectiveness and its impact on physical performance. Quality in Sport. Online. 28 July 2024. Vol. 19, p. 53183. [Accessed 28 June 2025]. DOI 10.12775/QS.2024.19.53183.
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Vol. 19 (2024)

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Medical Sciences

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Copyright (c) 2024 Paulina Cuper, Piotr Pawłucki, Anna Maciak, Michał Andrzej Kozicz, Ilona Jastrzębska, Krzysztof Bilecki, Hubert Gugulski, Michał Bado, Patrycja Nowoświat, Michał Sekuła

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