Relationships between electrical conductivity of acupuncture points and adaptation hormones
DOI:
https://doi.org/10.12775/QS.2024.21.53009Keywords
acupuncture points, electrical conductivity, adaptation hormones, relationshipsAbstract
Background. Modern scientific research has shown that the inherent regulatory system of the body is a neuro-endocrine-immune (NEI) network. A researcher proposed a hypothesis, that the bidirectional positive regulatory role of acupuncture was achieved by NEI network. The purpose of this study is to find out relationships between electrical conductivity (EC) of acupuncture points (AP) and adaptation hormones one of the elements of NEI network. Materials and methods. The object of observation were 10 women (32-76 years) and 10 men (37-67 years) examined twice with a weekly interval. The volunteers were considered practically healthy, but with maladaptation. We recorded EC in AP Pg(ND), TR(X) and MC(AVL) (by complex “Medissa”) as well as serum Cortisol, Aldosterone, Testosterone, Triiodothyronine, Calcitonin and PTH (by the ELISA). For statistical analysis used the software package "Statistica 6.4".
Results. The multiple linear regression analysis revealed the closest relationship with AP Testosterone raw level (R=0,485). Testosterone level, normalized by sex and age, was associated with AP to the same extent (R=0,439), but positive correlations were transformed into negative ones. Calcitonin level was also moderately positively correlated with AP (R=0,441). PTH was significantly correlated only with TR(X) lateralization (r=-0,363; p=0,022) and Triiodothyronine only with MC(AVL) lateralization (r=0,315; p=0,048). The connections of Aldosterone with AP lateralization turned out to be insignificant, and from the side of Cortisol, they were negligible at all. Despite moderate pairwise correlations, the canonical correlation between the levels of adaptation Hormones, on the one hand, and EC of AP and their lateralization, on the other hand, turned out to be quite strong (R=0,856). Conclusion. Electrical conductivity of AP and their lateralization is 73% determined by the constellation of adaptation hormones, which are an important component of the NEI network. In the next message, we will demonstrate the existence of connections between AP and parameters of EEG and heart rate variability as well as Immunity.
References
Babelyuk, V. Y., Popovych, I. L., Gozhenko, A. I., Dubkova, G. I., Kozyavkina, O. V., Korolyshyn, T. A., Babelyuk, N. V., Kovbanyuk, M. M., Fihura, O. A., Dobrovolskyi, Y. G., Zukow, W., & Yanchij, R. I. (2023). Gas Discharge Vizualization (Electrophotonic Imaging, Kirlianography). Theoretical and Applied Aspects. Feniks. https://doi.org/10.5281/zenodo.7535880
Babelyuk, V., Gozhenko, A., Dubkova, G., Babelyuk, N., Zukow, W., Kovbasnyuk, M., & Popovych, I. (2017). Causal relationships between the parameters of gas discharge visualization and principal neuroendocrine factors of adaptation. Journal of Physical Education and Sport, 17(2), 624-637. https://doi.org/10.7752/jpes.2017.02094
Babelyuk, V., Tserkovniuk, R., Babelyuk, N., Zukow, X., Ruzhylo, S., Dubkova, G., Korolyshyn, T., Hubyts’kyi, V., Kikhtan, V., Gozhenko, A., & Popovych, I. (2021). The parameters of gas discharge visualization (biophotonics) correlated with parameters of acupuncture points, EEG, HRV and hormones. Journal of Education, Health and Sport, 11(12), 359–373. https://doi.org/10.12775/jehs.2021.11.12.030
Babelyuk, V., Tserkovniuk, R., Dubkova, G., Kruhliy, Y., Korolyshyn, T., Babelyuk, N., Zukow, W., Ruzhylo, S., Fihura, O., Gozhenko, A., & Popovych, I. (2022). Relationships between the neuro-endocrine parameters and virtual chakras energy and asymmetry. Journal of Education, Health and Sport, 12(1), 235-249.
Besedovsky, H., & del Rey, A. (1996). Immune-neuro-endocrine interactions: facts and hypotheses. Endocrine Reviews, 17(1), 64–102. https://doi.org/10.1210/edrv-17-1-64
Bista, S., Jasti, N., Bhargav, H., Sinha, S., Gupta, S., Ramarao, P., Chaturvedi, S., & Gangadhar, B. (2022). Applications of Gas Discharge Visualization Imaging in Health and Disease: A Systematic Review. Alternative Therapies in Health and Medicine, AT6764. PMID: 35648690.
Chase, C. (2018). The Geometry of Emotions: Using Chakra Acupuncture and 5-Phase Theory to Describe Personality Archetypes for Clinical Use. Medical Acupuncture, 30(4), 167–178. https://doi.org/10.1089/acu.2018.1288
Cheng, K., & Tian, S. L. (2012). Effects of preventive-electroacupuncture of ‘‘Guanyuan’’ (CV4) and Sanyinjiao’’ (SP6) on hypothalamus-pituitary-ovary axis in ovariectomized rats. Acupuncture Research, 37, 15–19, 45.
Cui, J., Song, W., Jin, Y., Xu, H., Fan, K., Lin, D., ... & Lin, J. (2021). Research progress on the mechanism of the acupuncture regulating neuro-endocrine-immune network system. Veterinary Sciences, 8(8), 149.
Ding, S. S., Hong, S. H., Wang, C., Guo, Y., Wang, Z. K., & Xu, Y. (2014). Acupuncture modulates the neuro–endocrine–immune network. QJM: An International Journal of Medicine, 107(5), 341-345.
Eshkevari, L., Permaul, E., & Mulroney, S. E. (2013). Acupuncture blocks cold stress-induced increases in the hypothalamus-pituitary-adrenal axis in the rat. Journal of Endocrinology, 217, 95–104.
Gozhenko, A., Zantaraia, T., Zukow, W. (2024). „Falling values”: artifacts or source of unique information? Drastically low electrical conductivity of acupuncture points is accompanied by significant deviations of EEG, HRV, immunity, metabolism and GDV parameters. Quality in Sport. 17:51006. dx.doi.org/10.12775/QS.2024.17.004
Hong, H. (2019). Increase in electrodermal activity on acupuncture points of lymphatic, lung, nervous, endocrine and heart meridians after running exercise, a single case study. OBM Integrative and Complementary Medicine, 4(1), 1-15.
Korda, M., Gozhenko, A., Fihura, O., Popovych, D., Żukow, X. & Popovych, I. (2021). Relationships between plasma levels of main adaptogene hormones and EEG&HRV parameters at human with dysadaptation. Journal of Education, Health and Sport. 11(12), 492-512. https://doi.org/10.12775/jehs.2021.11.12.040
Korotkov, K. (2018). Principles of the human body functioning and their applications in integrative medicine (review). Journal of Applied Biotechnology and Bioengineering, 5(6), 346‒348.
Korotkov, K. (2018). Review of EPI papers on medicine and psychophysiology published in 2008-2018. Int J Complement Alt Med. 11(5), 311-315.
Kozyavkina, N., Popovych, I., Popovych, D., Zukow W. & Bombushkar, I. (2021). Sexual dimorphism in some psycho-neuro-endocrine parameters at human. Journal of Education, Health and Sport, 11(5), 370-391. https://doi.org/10.12775/jehs.2021.11.05.039
Newberg, A., Alavi, A., Baime, M., Pourdehnad, M., Santanna, J. & d’Aquili, E. (2001). The measurement of regional cerebral blood flow during the complex cognitive task of meditation: A preliminary SPECT study. Psychiatry Research: Neuroimaging Section, 106, 113-122.
Polovynko, I. S., Zajats, L. M., Zukow, W., Yanchij, R. I., & Popovych, I. L. (2016). Quantitative evaluation of integrated neuroendocrine and immune responses to chronic stress in rat male. Journal of Education, Health and Sport, 6(8), 154-166.
Popovych, I. L., Gozhenko, A. I., Korda, M. M., Klishch, I. M., Popovych, D. V., & Zukow, W. (editors). (2022). Mineral Waters, Metabolism, Neuro-Endocrine-Immune Complex. Odesa. Feniks; 2022: 252.
Wang, S. (2010). Acupuncture Effect on Hypothalamus-pituitary-thyroid Axis in Multiple Stress Induced Rat Model of Chronic Fatigue. China: Liaoning University of Chinese Medicine.
Xu, J. Y., & Feng, Q. (1997). A hypothesis - the bidirectional positive regulatory role of acupuncture was achieved by neuro-endocrine-immune network. Journal of Guiyang College of Traditional Chinese Medicine, 19, 6–8.
Levin, M. (2014). Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo. Molecular Biology of the Cell, 25(24), 3835-3850. https://doi.org/10.1091/mbc.e13-12-0708
Long X., Huang W., Napadow V., Liang F., Pleger B., Villringer A.et al.. Sustained effects of acupuncture stimulation investigated with centrality mapping analysis. Frontiers in Human Neuroscience 2016;10. https://doi.org/10.3389/fnhum.2016.00510
Liu B., Chen J., Wang J., Liu X., Duan X., Shang X.et al.. Altered small-world efficiency of brain functional networks in acupuncture at st36: a functional mri study. Plos One 2012;7(6):e39342. https://doi.org/10.1371/journal.pone.0039342
Langevin H. and Yandow J.. Relationship of acupuncture points and meridians to connective tissue planes. The Anatomical Record 2002;269(6):257-265. https://doi.org/10.1002/ar.10185
Wang M., Liu W., Ge J., & Liu S.. The immunomodulatory mechanisms for acupuncture practice. Frontiers in Immunology 2023;14. https://doi.org/10.3389/fimmu.2023.1147718
Sun R.. Immunological studies on acupuncture and moxibustion treatment of rheumatoid arthritis: a review. Medicine 2024;103(2):e36875. https://doi.org/10.1097/md.0000000000036875
Yamaguchi N., Takahashi T., Sakuma M., Sugita T., Uchikawa K., Sakaihara S.et al.. Acupuncture regulates leukocyte subpopulations in human peripheral blood. Evidence-Based Complementary and Alternative Medicine 2000;4(4):447-453. https://doi.org/10.1093/ecam/nel107
Volf N.. Electriogram of associative «shu-points» as a diagnostic tool for diseases of the internal organs. International Journal of Complementary & Alternative Medicine 2017;9(3). https://doi.org/10.15406/ijcam.2017.09.00303
Sun R., Yang Y., Li Z., Li Y., & Zeng F.. Connectomics: a new direction in research to understand the mechanism of acupuncture. Evidence-Based Complementary and Alternative Medicine 2014;2014:1-9. https://doi.org/10.1155/2014/568429
Zhang K., Guo X., Yan Y., Liu Y., Xu Z., Zhao X.et al.. Applying statistical and complex network methods to explore the key signaling molecules of acupuncture regulating neuroendocrine-immune network. Evidence-Based Complementary and Alternative Medicine 2018;2018:1-17. https://doi.org/10.1155/2018/9260630
Li F., He T., Xu Q., Lin L., Li H., Liu Y.et al.. What is the acupoint? a preliminary review of acupoints. Pain Medicine 2015;16(10):1905-1915. https://doi.org/10.1111/pme.12761
Jeanneteau F., Lambert W., Ismaı̈li N., Bath K., Lee F., Garabedian M.et al.. Bdnf and glucocorticoids regulate corticotrophin-releasing hormone (crh) homeostasis in the hypothalamus. Proceedings of the National Academy of Sciences 2012;109(4):1305-1310. https://doi.org/10.1073/pnas.1114122109
Chen Y., Fang Y., Yang J., Wang F., Wang Y., & Li Y.. Effect of acupuncture on premature ovarian failure: a pilot study. Evidence-Based Complementary and Alternative Medicine 2014;2014:1-6. https://doi.org/10.1155/2014/718675
Li Q., Shi G., Xu Q., Wang J., Liu C., & Wang L.. Acupuncture effect and central autonomic regulation. Evidence-Based Complementary and Alternative Medicine 2013;2013:1-6. https://doi.org/10.1155/2013/267959
Wang J., Lu S., Fu Y., Guo Y., Chen Z., Yu N.et al.. The role of macrophage polarization and associated mechanisms in regulating the anti-inflammatory action of acupuncture: a literature review and perspectives. Chinese Medicine 2021;16(1). https://doi.org/10.1186/s13020-021-00466-7
Nurwati I., Muthmainah M., & Huda K.. Acupuncture for asthma: its potential significance in clinical practice. Medical Acupuncture 2020;32(5):272-279. https://doi.org/10.1089/acu.2020.1443
Ma Q.. Somato–autonomic reflexes of acupuncture. Medical Acupuncture 2020;32(6):362-366. https://doi.org/10.1089/acu.2020.1488
Dong H., Lüdicke F., Comte I., Campana A., Graff P., & Bischof P.. An exploratory pilot study of acupuncture on the quality of life and reproductive hormone secretion in menopausal women. The Journal of Alternative and Complementary Medicine 2001;7(6):651-658. https://doi.org/10.1089/10755530152755207
Liu X., Xie X., Li Y., Li M., Wang Y., Wang N.et al.. Efficacy of manual acupuncture versus placebo acupuncture for generalized anxiety disorder (gad) in perimenopause women : study protocol for a randomized controlled trial. 2021. https://doi.org/10.21203/rs.3.rs-577572/v1
Zhao Z., Lee B., Feng L., Guo Y., Wu Y., In S.et al.. Effects of acupuncture at zu-san-li (st36) on the activity of the hypothalamic–pituitary–adrenal axis during ethanol withdrawal in rats. Journal of Acupuncture and Meridian Studies 2014;7(5):225-230. https://doi.org/10.1016/j.jams.2014.03.002
Zhao Z., Kim S., Zhang J., Liu H., Lee B., Jang E.et al.. Hypothalamic norepinephrine mediates acupunctural effects on hypothalamic–pituitary–adrenal axis during ethanol withdrawal. Journal of Acupuncture and Meridian Studies 2016;9(1):4-10. https://doi.org/10.1016/j.jams.2015.05.007
Bryant A., Greenwood A., Juntti S., Byrne A., & Fernald R.. Dopaminergic inhibition of gonadotropin-releasing hormone neurons in the cichlid fish, astatotilapia burtoni. Journal of Experimental Biology 2016. https://doi.org/10.1242/jeb.147637
Webber K., Casadesús G., Marlatt M., Perry G., Hamlin C., Atwood C.et al.. Estrogen bows to a new master: the role of gonadotropins in alzheimer pathogenesis. Annals of the New York Academy of Sciences 2005;1052(1):201-209. https://doi.org/10.1196/annals.1347.020
Xu J., Fan Y., J G., Zhang Y., & T X.. The use of acupuncture as an alternative treatment method for ovarian dysfunction: a narrative review. Journal of Clinical Case Studies 2021;6(4). https://doi.org/10.16966/2471-4925.228
Cochrane S., Smith C., Possamai-Inesedy A., & Bensoussan A.. Acupuncture and women's health: an overview of the role of acupuncture and its clinical management in women's reproductive health. International Journal of Women S Health 2014:313. https://doi.org/10.2147/ijwh.s38969
Wang S., Zhang J., & Qie L.. Acupuncture relieves the excessive excitation of hypothalamic-pituitary-adrenal cortex axis function and correlates with the regulatory mechanism of gr, crh, and acthr. Evidence-Based Complementary and Alternative Medicine 2014;2014:1-9. https://doi.org/10.1155/2014/495379
Johansson J., Redman L., Veldhuis P., Sazonova A., Labrie F., Holm G.et al.. Acupuncture for ovulation induction in polycystic ovary syndrome: a randomized controlled trial. Ajp Endocrinology and Metabolism 2013;304(9):E934-E943. https://doi.org/10.1152/ajpendo.00039.2013
González-González M., Romero K., Beitter J., Lloyd D., Lam D., Hernandez-Reynoso A.et al.. Renal nerve activity and arterial depressor responses induced by neuromodulation of the deep peroneal nerve in spontaneously hypertensive rats. Frontiers in Neuroscience 2022;16. https://doi.org/10.3389/fnins.2022.726467
Qu F., Zhou J., & Nan R.. Acupuncture for perimenopausal symptoms in women who underwent oophorectomy – a comparative study. Complementary Medicine Research 2007;14(1):25-32. https://doi.org/10.1159/000098799
Sunay D., Ozdiken M., Arslan H., Seven A., & Aral Y.. The effect of acupuncture on postmenopausal symptoms and reproductive hormones: a sham controlled clinical trial. Acupuncture in Medicine 2011;29(1):27-31. https://doi.org/10.1136/aim.2010.003285
Li X., Wu K., Dong Q., Chen H., Li C., Ren Z.et al.. Overall adjustment acupuncture improves osteoporosis and exerts an endocrine-modulating effect in ovariectomized rats. Frontiers in Endocrinology 2022;13. https://doi.org/10.3389/fendo.2022.1074516
Lin G., Liu X., Cong C., Chen S., & Xu L.. Clinical efficacy of acupuncture for diminished ovarian reserve: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Endocrinology 2023;14. https://doi.org/10.3389/fendo.2023.1136121
Painovich J., Shufelt C., Azziz R., Yang Y., Goodarzi M., Braunstein G.et al.. A pilot randomized, single-blind, placebo-controlled trial of traditional acupuncture for vasomotor symptoms and mechanistic pathways of menopause. Menopause the Journal of the North American Menopause Society 2012;19(1):54-61. https://doi.org/10.1097/gme.0b013e31821f9171
Yang Y., Zhou C., Hu H., Fukuzawa I., & Zhang H.. Underlying mechanisms of acupuncture therapy on polycystic ovary syndrome: evidences from animal and clinical studies. Frontiers in Endocrinology 2022;13. https://doi.org/10.3389/fendo.2022.1035929
Xu H., Zheng C., He L., Su T., Wang H., Yu L.et al.. Effect of acupuncture on women with poor ovarian response: a study protocol for a multicenter randomized controlled trial. Trials 2020;21(1). https://doi.org/10.1186/s13063-020-04690-8
Wang Y., Li Y., Chen R., Cui X., Yu J., & Liu Z.. Electroacupuncture for reproductive hormone levels in patients with diminished ovarian reserve: a prospective observational study. Acupuncture in Medicine 2016;34(5):386-391. https://doi.org/10.1136/acupmed-2015-011014
Wang S., Lin S., Mingmin Z., Li C., Chen S., Liu P.et al.. Acupuncture reduces apoptosis of granulosa cells in rats with premature ovarian failure via restoring the pi3k/akt signaling pathway. International Journal of Molecular Sciences 2019;20(24):6311. https://doi.org/10.3390/ijms20246311
Pan Y., Yang K., Shi X., Liang H., Shen X., Wang R.et al.. Clinical benefits of acupuncture for the reduction of hormone therapy–related side effects in breast cancer patients: a systematic review. Integrative Cancer Therapies 2018;17(3):602-618. https://doi.org/10.1177/1534735418786801
Yuan Y., Xia Q., Cui W., Cao W., Zhou Z., Peng J.et al.. Study on the mechanism of action of different acupuncture regimens on premature ovarian failure model rats. Computational and Mathematical Methods in Medicine 2022;2022:1-10. https://doi.org/10.1155/2022/5254628
Li Y., Zhu B., Rong P., Ben H., & Lǐ Y.. Neural mechanism of acupuncture-modulated gastric motility. World Journal of Gastroenterology 2007;13(5):709. https://doi.org/10.3748/wjg.v13.i5.709
Liu C., Wang Z., Guo T., Zhuang L., & Gao X.. Effect of acupuncture on menopausal hot flushes and serum hormone levels: a systematic review and meta-analysis. Acupuncture in Medicine 2021;40(4):289-298. https://doi.org/10.1177/09645284211056655
Liu R., He M., Sun M., Wang L., Cao J., Yu Q.et al.. Application of fmri techniques in the study of acupuncture for gynecological diseases: a review. Medicine 2023;102(10):e33268. https://doi.org/10.1097/md.0000000000033268
Li Y., Zhu B., Rong P., Ben H., & Lǐ Y.. Neural mechanism of acupuncture-modulated gastric motility. World Journal of Gastroenterology 2007;13(5):709. https://doi.org/10.3748/wjg.v13.i5.709
Cruz J., Carrington L., & Hong H.. A feasibility study on treatment of uterine fibroids with tung's acupuncture. Medical Acupuncture 2019;31(6):384-391. https://doi.org/10.1089/acu.2019.1385
Shang C.. Prospective tests on biological models of acupuncture. Evidence-Based Complementary and Alternative Medicine 2000;6(1):31-39. https://doi.org/10.1093/ecam/nem122
Zhu H.. Acupoints initiate the healing process. Medical Acupuncture 2014;26(5):264-270. https://doi.org/10.1089/acu.2014.1057
Arsovska B. and Kozovska K.. Case report - acupuncture treatment in patient with hormonal imbalance. International Journal of Research -Granthaalayah 2021;9(6):307-310. https://doi.org/10.29121/granthaalayah.v9.i6.2021.4046
Curtis P., Coeytaux R., & Hapke P.. Acupuncture for birth preparation and delivery: how investigating mechanisms of action can generate research. Complementary Health Practice Review 2006;11(3):176-192. https://doi.org/10.1177/1533210106298060
Hershman D., Unger J., Greenlee H., Capodice J., Lew D., Darke A.et al.. Effect of acupuncture vs sham acupuncture or waitlist control on joint pain related to aromatase inhibitors among women with early-stage breast cancer. Jama 2018;320(2):167. https://doi.org/10.1001/jama.2018.8907
Xu C., Yu X., Yin L., Li X., Zhang W., Li F.et al.. Functional magnetic resonance imaging study of electroacupuncture stimulating uterine acupoints. Computational and Mathematical Methods in Medicine 2022;2022:1-5. https://doi.org/10.1155/2022/4295985
Y S.. Positive effects of acupuncture on menstrual irregularity and infertility in a patient with polycystic ovary syndrome. Family Medicine & Medical Science Research 2014;03(02). https://doi.org/10.4172/2327-4972.1000121
Ahn A., Wu J., Badger G., Hammerschlag R., & Langevin H.. Electrical impedance along connective tissue planes associated with acupuncture meridians. BMC Complementary and Alternative Medicine 2005;5(1). https://doi.org/10.1186/1472-6882-5-10
Mao J. and Kapur R.. Acupuncture in primary care. Primary Care Clinics in Office Practice 2010;37(1):105-117. https://doi.org/10.1016/j.pop.2009.09.010
Gunec C.. A review on acupuncture (the relationship between chinese acupuncture points and blood and lymph vessels and nerves in western medicine). J Tradi Med and Chin Med 2023:1-5. https://doi.org/10.47363/jtmcm/2023(1)102
Zhu J., Li J., & Liu S.. Acupuncture, from the ancient to the current. The Anatomical Record 2021;304(11):2365-2371. https://doi.org/10.1002/ar.24625
Sibbritt D., Adams J., & Young A.. The characteristics of middle aged australian women who consult acupuncturists. Acupuncture in Medicine 2007;25(1-2):22-28. https://doi.org/10.1136/aim.25.1-2.22
Park J., Ryu Y., Liu Y., Jung H., Kim A., Jung S.et al.. A literature review of de qi in clinical studies. Acupuncture in Medicine 2013;31(2):132-142. https://doi.org/10.1136/acupmed-2012-010279
P S.. Exploring the efficacy of auricular acupuncture in managing type 2 diabetes mellitus utilizing freestyle libre pro continuous glucose monitoring as the primary outcome measure: a pilot randomized controlled trial protocol. 2024. https://doi.org/10.21203/rs.3.rs-4429477/v1
Ahn A., Colbert A., Anderson B., Martinsen Ø., Hammerschlag R., Cina S.et al.. Electrical properties of acupuncture points and meridians: a systematic review. Bioelectromagnetics 2008;29(4):245-256. https://doi.org/10.1002/bem.20403
Dimitrova A., Murchison C., & Oken B.. Local effects of acupuncture on the median and ulnar nerves in patients with carpal tunnel syndrome: a pilot mechanistic study protocol. Trials 2019;20(1). https://doi.org/10.1186/s13063-018-3094-5
Liu C., Zheng S., Wu W., Wang X., Qin S., Yu-hong Z.et al.. Effects of acupuncture on the hypothalamus-pituitary-adrenal axis in chronic insomnia patients: a study protocol for a randomized controlled trial. Trials 2019;20(1). https://doi.org/10.1186/s13063-019-3964-5
Lee B.. Needling point location used in sham acupuncture for chronic nonspecific low back pain. Jama Network Open 2023;6(9):e2332452. https://doi.org/10.1001/jamanetworkopen.2023.32452
Yuan Y., Xia Q., Cui W., Cao W., Zhou Z., Peng J.et al.. Study on the mechanism of action of different acupuncture regimens on premature ovarian failure model rats. Computational and Mathematical Methods in Medicine 2022;2022:1-10. https://doi.org/10.1155/2022/5254628
Cabioglu M.. A glance at the acupuncture point from the perspective of current technology. Oalib 2016;03(03):1-5. https://doi.org/10.4236/oalib.1102237
Han Y.. Bibliometric analysis: hot spots and frontiers in acupuncture treatment of cerebral infarction. Medicine 2024;103(15):e37800. https://doi.org/10.1097/md.0000000000037800
Zhang N., Zhang H., Zhang X., Zhang B., Wang F., Wang C.et al.. The relationship between endogenous testosterone and lipid profile in middle-aged and elderly chinese men. Acta Endocrinologica 2014;170(4):487-494. https://doi.org/10.1530/eje-13-0802
Syam Kumar C P, Venketeswaran S T, Geethanjali Sankar et al. Exploring the Efficacy of Auricular Acupuncture in Managing Type 2 Diabetes Mellitus Utilizing Freestyle Libre Pro Continuous Glucose Monitoring as the Primary Outcome Measure: A Pilot Randomized Controlled Trial Protocol, 06 June 2024, PREPRINT (Version 1) available at Research Square https://doi.org/10.21203/rs.3.rs-4429477/v1
Adams D., Tseng A., & Levin M.. Light-activation of the archaerhodopsin h+-pump reverses age-dependent loss of vertebrate regeneration: sparking system-level controls in vivo. Biology Open 2013;2(3):306-313. https://doi.org/10.1242/bio.20133665
Wang Q., Deng H., Cheng K., Huang Z., Yin X., Zhou Y.et al.. Manual acupuncture for the infertile female with polycystic ovary syndrome (pcos): study protocol for a randomized sham-controlled trial. Trials 2019;20(1). https://doi.org/10.1186/s13063-019-3667-y
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Toto Zantaraia, Anatoliy Gozhenko, Igor Popovych
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Stats
Number of views and downloads: 374
Number of citations: 0
