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Quality in Sport

The treatment of hyperphagia and obesity in Prader-Willi Syndrome
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  • The treatment of hyperphagia and obesity in Prader-Willi Syndrome
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The treatment of hyperphagia and obesity in Prader-Willi Syndrome

Authors

  • Ilona Jastrzębska Grochowski Hospital, Grenadierow 51/59 Street, 04-073 Warsaw, Poland https://orcid.org/0000-0001-6754-529X
  • Paulina Cuper Brothers Hospitallers of Saint John of God Hospital in Cracow; Trynitarska 11 Street, 31-061 Kraków, Poland https://orcid.org/0009-0007-5386-4338
  • Michał Andrzej Kozicz Brothers Hospitallers Hospital in Kraków, Trynitarska 11, 31-061 Kraków, Poland https://orcid.org/0009-0001-4254-4087
  • Krzysztof Bilecki SP ZOZ MSWiA, Kronikarza Galla 25, 30-053 Cracow, Poland https://orcid.org/0009-0001-8778-1422
  • Hubert Gugulski Jagiellonian University Medical College ul. Św Anny 12, 31-008 Kraków https://orcid.org/0009-0004-1294-9835
  • Michał Bado The University Hospital in Krakow, Jakubowskiego 2 Street, 30-688 Krakow, Poland https://orcid.org/0009-0008-6595-6560
  • Patrycja Nowoświat The University Hospital in Krakow, Jakubowskiego 2 Street, 30-688 Krakow, Poland https://orcid.org/0009-0008-7939-6621

DOI:

https://doi.org/10.12775/QS.2024.17.52948

Keywords

Prader-Willi syndrome, obesity, treatment

Abstract

Introduction: Prader-Willi Syndrome (PWS) is a genetic neurodevelopmental disorder, in which the central clinical characteristics are hyperphagia and obesity. Obesity leads to higher mortality rates in PWS patients and thus, effective and safe treatment of hyperphagia and obesity in PWS individuals is an important aspect of PWS therapy.

Aim of the study: The aim of the study was to research both the new and the more standard treatment options of hyperphagia and obesity in PWS patients.

Methods and Materials: An extensive literature search was conducted using PubMed database. Only articles from the past 5 years were taken into consideration. The keywords used during the search were: prader willi syndrome, obesity, treatment.

Results: Our research showed that in the treatment of hyperphagia and obesity in PWS patients, health professionals may consider the use of pharmacological treatment options, surgery and neuromodulatory options. Moreover, physical activity and environmental control are beneficial in limiting caloric intake and improving body mass index. Furthermore, early diagnosis and thus starting treatment in early childhood are beneficial in preventing the progression of obesity. However, more research is needed to determine which treatment options are best suited for specific patients. 

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Published

2024-07-18

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JASTRZĘBSKA, Ilona, CUPER, Paulina, KOZICZ, Michał Andrzej, BILECKI, Krzysztof, GUGULSKI, Hubert, BADO, Michał and NOWOŚWIAT, Patrycja. The treatment of hyperphagia and obesity in Prader-Willi Syndrome. Quality in Sport. Online. 18 July 2024. Vol. 17, p. 52948. [Accessed 8 July 2025]. DOI 10.12775/QS.2024.17.52948.
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Vol. 17 (2024)

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Copyright (c) 2024 Ilona Jastrzębska, Paulina Cuper, Michał Andrzej Kozicz, Krzysztof Bilecki, Hubert Gugulski, Michał Bado, Patrycja Nowoświat

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