Impact of Obesity on Respiratory Health: The Role of Sport and Physical Activity in Prevention and Management
DOI:
https://doi.org/10.12775/QS.2024.15.52231Keywords
Obesity, Respiratory Diseases, Physical Activity, Obstructive Sleep Apnea, Obesity Hypoventilation SyndromeAbstract
Introduction and Objective: Obesity is a major social and economic problem. Since the 1980s, the number of overweight and obese people has doubled. Treatment of such patients is 30% more expensive than for people of normal weight. The main aim of the article is to present the impact of the occurrence of respiratory diseases and the deterioration of the system function. In addition, the article reviews the impact of physical activity and diet on weight loss and the prevention of further weight gain.
Review and Methods: Review and summary of studies and meta-analysis of studies available in open-source format on Google Scholar and PubMed.
Abbreviated Description of the State of Knowledge: One of the most common diseases in the population is bronchial asthma. People with excess body weight have a more severe course, and numerous studies have been carried out to explain the cause. The main mechanism that worsens respiratory function is mechanical compression by fatty tissue. It has also been observed that the inflammatory response, underlying the etiopathogenesis of asthma, may be caused by the secretion of inflammatory mediators by adipocytes. This is currently being investigated.
Obstructive sleep apnea is a disorder that results in a fragmentation of sleep, which has serious health consequences and leads to a reduction in quality of life. Obesity is a major risk factor. The severity of the condition is strongly related to excess body weight.
Obese hypoventilation syndrome is a condition in which obesity impairs alveolar
ventilation and CO2 removal, resulting in hypercapnia, which can lead to respiratory failure.
Summary: Weight loss and interventions to prevent weight gain in people with a baseline BMI >25 kg/m2 are fundamental to good health. For best results, a calorie-restricted diet should be combined with physical activity. The WHO has created recommendations for the amount of physical activity needed each week.
References
Kendall, B. J., Rubenstein, J. H., Cook, M. B., Vaughan, T. L., Anderson, L. A., Murray, L. J., Shaheen, N. J., Corley, D. A., Chandar, A. K., Li, L., Greer, K. B., Chak, A., El-Serag, H. B., Whiteman, D. C., & Thrift, A. P. (2016). Inverse association between gluteofemoral obesity and risk of Barrett’s esophagus in a pooled analysis. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, 14(10), 1412-1419.e3. https://doi.org/10.1016/j.cgh.2016.05.032
Lin, X., & Li, H. (2021). Obesity: Epidemiology, pathophysiology, and therapeutics. Frontiers in Endocrinology, 12. https://doi.org/10.3389/fendo.2021.706978
Wong, M. C. S., Huang, J., Wang, J., Chan, P. S. F., Lok, V., Chen, X., Leung, C., Wang, H. H. X., Lao, X. Q., & Zheng, Z.-J. (2020). Global, regional and time-trend prevalence of central obesity: a systematic review and meta-analysis of 13.2 million subjects. European Journal of Epidemiology, 35(7), 673–683. https://doi.org/10.1007/s10654-020-00650-3
WHO. Waist Circumference and Waist–Hip Ratio: Report of a WHO Expert Consultation 8–11 December ed. Geneva; 2008. p. 47. https://www.who.int/publications/i/item/9789241501491
Carey DGP. Abdominal obesity. Curr Opin Lipidol. 1998;9(1):35–40.
DOI: 10.1097/00041433-199802000-00008
WHO Consultation on Obesity (1999: Geneva, Switzerland) & World Health Organization. Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation. World Health Organ Tech Rep Ser (2000) 894:i–xii, 1-253
Singh RK, Kumar P, Mahalingam K. Molecular Genetics of Human Obesity: A Comprehensive Review. C R Biol (2017) 340(2):87–108. doi: 10.1016/j.crvi.2016.11.007
DOI: 10.1016/j.crvi.2016.11.007
Sacks FM, Bray GA, Carey VJ, Smith SR, Ryan DH, Anton SD, et al. Comparison of Weight-Loss Diets With Different Compositions of Fat, Protein, and Carbohydrates. N Engl J Med (2009) 360(9):859–73. doi: 10.1056/NEJMoa0804748
DOI: 10.1056/NEJMoa0804748
Ataey A, Jafarvand E, Adham D, Moradi-Asl E. The Relationship Between Obesity, Overweight, and the Human Development Index in World Health Organization Eastern Mediterranean Region Countries. J Prev Med Public Health (2020) 53(2):98–105. doi: 10.3961/jpmph.19.100
DOI:10.3961/jpmph.19.100
Sutherland, E. R. (2014). Linking obesity and asthma. Annals of the New York Academy of Sciences, 1311(1),31–41. https://doi.org/10.1111/nyas.12357
2011. Vital signs: asthma prevalence, disease characteristics, and self-management education: United States, 2001–2009. Morb. Mortal. Wkly. Rep. 60: 547–552.
Beuther, D.A. & E.R. Sutherland. 2007. Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies. Am. J. Respir. Crit. Care Med. 175: 661–666. DOI: 10.1164/rccm.200611-1717OC. DOI: 10.1164/rccm.200611-1717OC
Nystad, W., H.E. Meyer, P. Nafstad, et al. 2004. Body mass index in relation to adult asthma among 135,000 Norwegian men and women. Am. J. Epidemiol. 160: 969–976.
DOI: 10.1093/aje/kwh303
Biring, M.S., M.I. Lewis, J.T. Liu & Z. Mohsenifar. 1999. Pulmonary physiologic changes of morbid obesity. Am. J. Med. Sci. 318: 293–297. DOI: 10.1097/00000441-199911000-00002
Beuther, D.A. & E.R. Sutherland. Obesity and pulmonary function testing. J. Allergy Clin. Immunol. 2005; 115: 1100–1101. DOI: 10.1016/j.jaci.2004.12.1141
Sierra-Honigmann, M.R, A.K. Nath, C. Murakami, et al. 1998. Biological action of leptin as an angiogenic factor. Science 281: 1683–1686. DOI: 10.1126/science.281.5383.1683
Todd, D.C., S. Armstrong, L. D'Silva, et al. 2007. Effect of obesity on airway inflammation: a cross-sectional analysis of body mass index and sputum cell counts. Clin. Exp. Allergy 37: 1049–1054. DOI: 10.1111/j.1365-2222.2007.02748.x
McLachlan, C.R., R. Poulton, G. Car, et al. 2007. Adiposity, asthma, and airway inflammation. J. Allergy Clin. Immunol. 119: 634–639. DOI: 10.1016/j.jaci.2006.10.029
Desai, D., C. Newby, F.A. Symon, et al. 2013. Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma. Am. J. Respir. Crit. Care Med. 188: 657–663. DOI: 10.1164/rccm.201208-1470OC
Holgate, S. T. (2008). Pathogenesis of asthma. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology, 38(6), 872–897. https://doi.org/10.1111/j.1365-2222.2008.02971.x
Trojanowski, T. (2019). Infekcje układu oddechowego—czy mają związek z otyłością?. In Forum Medycyny Rodzinnej (Vol. 13, No. 6, pp. 292-299).
Lv, R., Liu, X., Zhang, Y., Dong, N., Wang, X., He, Y., Yue, H., & Yin, Q. (2023). Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome. Signal Transduction and Targeted Therapy, 8(1), 1–46. https://doi.org/10.1038/s41392-023-01496-3
Wyszomirski, K., Walędziak, M., & Różańska-Walędziak, A. (2023). Obesity, bariatric surgery and obstructive sleep apnea—A narrative literature review. Medicina (Kaunas, Lithuania), 59(7), 1266. https://doi.org/10.3390/medicina59071266
Carneiro-Barrera, A., Amaro-Gahete, F. J., Guillén-Riquelme, A., Jurado-Fasoli, L., Sáez-Roca, G., Martín-Carrasco, C., Buela-Casal, G., & Ruiz, J. R. (2022). Effect of an interdisciplinary weight loss and lifestyle intervention on obstructive sleep apnea severity: The INTERAPNEA randomized clinical trial. JAMA Network Open, 5(4), e228212. https://doi.org/10.1001/jamanetworkopen.2022.8212
Krishnan, A., Ellis, P., Antoine-Pitterson, P., Oakes, A., Jones, B., Turner, A., & Mukherjee, R. (2023). Long-term mortality following acute noninvasive ventilation for obesity-related respiratory failure: A retrospective single-centre study. Canadian Respiratory Journal: Journal of the Canadian Thoracic Society, 2023, 1–7. https://doi.org/10.1155/2023/5370197
Dougherty, M., Lomiguen, C. M., Chin, J., & McElroy, P. K. (2021). Obesity hypoventilation syndrome-related challenges in acute respiratory failure. Cureus, 13(9). https://doi.org/10.7759/cureus.18066
Ramírez Molina, V. R., Masa Jiménez, J. F., Gómez de Terreros Caro, F. J., & Corral Peñafiel, J. (2020). Effectiveness of different treatments in obesity hypoventilation syndrome. Pulmonology, 26(6), 370–377. https://doi.org/10.1016/j.pulmoe.2020.05.012
Obesity-Hypoventilation Syndrome Marsha H. Antoine, Abdulghani Sankari 1 , Pradeep C. Bollu 2 https://www.ncbi.nlm.nih.gov/books/NBK482300/
Hill, J. O., & Wyatt, H. R. (2005). Role of physical activity in preventing and treating obesity. Journal of Applied Physiology (Bethesda, Md.: 1985), 99(2), 765–770. https://doi.org/10.1152/japplphysiol.00137.2005
https://www.who.int/news-room/fact-sheets/detail/physical-activity
Oktay, A. A., Lavie, C. J., Kokkinos, P. F., Parto, P., Pandey, A., & Ventura, H. O. (2017). The interaction of cardiorespiratory fitness with obesity and the obesity paradox in cardiovascular disease. Progress in Cardiovascular Diseases, 60(1), 30–44. https://doi.org/10.1016/j.pcad.2017.05.005
Swift, D. L., McGee, J. E., Earnest, C. P., Carlisle, E., Nygard, M., & Johannsen, N. M. (2018). The effects of exercise and physical activity on weight loss and maintenance. Progress in Cardiovascular Diseases, 61(2), 206–213. https://doi.org/10.1016/j.pcad.2018.07.014
Jakicic, J. M., Rogers, R. J., Davis, K. K., & Collins, K. A. (2018). Role of physical activity and exercise in treating patients with Overweight and obesity. Clinical Chemistry, 64(1), 99–107. https://doi.org/10.1373/clinchem.2017.272443
Washburn, R. A., Szabo, A. N., Lambourne, K., Willis, E. A., Ptomey, L. T., Honas, J. J., Herrmann, S. D., & Donnelly, J. E. (2014). Does the method of weight loss effect long-term changes in weight, body composition or chronic disease risk factors in overweight or obese adults? A systematic review. PloS One, 9(10), e109849. https://doi.org/10.1371/journal.pone.0109849
Goodpaster, B. H., DeLany, J. P., Otto, A. D., Kuller, L., Vockley, J., South-Paul, J. E., Thomas, S. B., Brown, J., McTigue, K., Hames, K. C., Lang, W., & Jakicic, J. M. (2010). Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults: A randomized trial. JAMA: The Journal of the American Medical Association, 304(16), 1795. https://doi.org/10.1001/jama.2010.1505
Chin, S.-H., Kahathuduwa, C. N., & Binks, M. (2016). Physical activity and obesity: what we know and what we need to know. Obesity Reviews: An Official Journal of the International Association for the Study of Obesity, 17(12), 1226–1244. https://doi.org/10.1111/obr.12460
Donnelly, J. E., Blair, S. N., Jakicic, J. M., Manore, M. M., Rankin, J. W., & Smith, B. K. (2009). Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Medicine and Science in Sports and Exercise, 41(2), 459–471. https://doi.org/10.1249/mss.0b013e3181949333
Ross, R. (2000). Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men: A randomized, controlled trial. Annals of Internal Medicine, 133(2), 92. https://doi.org/10.7326/0003-4819-133-2-200007180-00008
Després, J. P. (2006). Intra-abdominal obesity: an untreated risk factor for Type 2 diabetes and cardiovascular disease. Journal of Endocrinological Investigation, 29(3 Suppl). https://pubmed.ncbi.nlm.nih.gov/16751711/
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Copyright (c) 2024 Rafał Makuch, Adam Kucharski, Konrad Pilarski, Alicja Chrościcka , Kamil Gała, Andrzej Czajka, Paweł Lenard, Sara Michalska, Martyna Dewicka, Alicja Maria Wawrzyniak
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