The evaluation of nutritional status disorders as a state of overweight and hyperlipidemia in children with cancer
DOI:
https://doi.org/10.12775/MBS.2014.035Keywords
cancer in children, obesity, hyperlipidemiaAbstract
A i m o f s t u d y . The assessment of nutritional status with a special attention towards overweight by anthropometric measurements and biochemical parameters of lipids in children with cancer.
Ma t e r i a l a n d m e t h o d s . In a retrospective group data of 122 patients’ treatment history were analyzed. The patients were treated in our hospital in previous years and their weight and height were studied. In a prospective group 62 newly diagnosed children with cancer were examined. The additional anthropometric measurements were included in the research like skinfolds thickness and middle arm circumference and biochemical lipids date were taken. The data were analyzed three times: at the diagnosis, during the oncological treatment and after the intensive chemotherapy.
R e s u l t s . In a retrospective group, after the oncological treatment the number of children with overweight increased: M/W>90 ile 6.6%, BMI >90 ile 6.6%, %IBW above 110% 25.5%, Cole’a index above 110% 21.3% , whereas the number of children with height > 90 ile decreased to 6.6%. At the beginning, in a prospective group the number of children with overweight was three times higher-11.3%. 26.2% patients had abnormal level of triglicerydes at diagnosis and 30.4% after treatment. Above 50% of patients had abnormal level of HDL cholesterol during the whole treatment.
C o n c l u s i o n s . Children with cancer belong to the group of risk for obesity and hyperlipidemia during the oncological treatment and it may impact on treatment and outcomes and also have serious medical consequence to the health state in future.
References
Warner JT, Evans WD, Webb DKH, Gregory JW: Body composition of long-term survivors of acute lymphoblastic leukemia. Med Pediatr Oncol 2002, 38: 165-172.
Rogers PC, Meacham LR, Oeffinger KC, Henry DW, Lange BJ: Obesity in Pediatric Oncology. Pediatr Blood Cancer 2005, 45: 881-891.
Lange BJ, Gerbing RB, Feusner J, Skolnik J, Sacks N, Smith FO, Alonzo TA: Mortality in overweight and underweight children with acute myeloid leukemia. JAMA 2005, 293: 203-211.
Grabiński M. Hiperlipidemie u dzieci. Adv Clin Exp Med 2007, 16:165-171.
Dziechciarz P, Horvath A, Szajewska H: Zaburzenia lipidowe u dzieci - czas na stosowanie terapii farmakologicznej?. Pediatr. Współcz. Gastroenetrol. Hepatol. Żywienie Dziecka 2008, 10: 199-202.
Aronne LJ: Classification of obesity and assessment of obesity-related health risk. Obes Res 2002, 10 (suppl.2): 105-115.
Grześk G, El-Essa A, Kubica A, Grześk E, Kubica J, Koziński M: Rosuwastatyna w prewencji pierwotnej schorzeń układu sercowo-naczyniowego. Folia Cardiol Excerpta 2010, 5: 141-144.
Jarosz M, Rychlik E: Overweight and obesity among adults in Poland, 1983-2005. Adv Med Sci 2008, 53:158- 166.
Jarosz M, Dzieniszewski J, Szczygieł B, Długosz J, Marlicz K, Linke K, Bułhak-Jachymczyk B, Panczenko- Kresowska B, Nekanda-Trepka A, Jaroszewicz- Heigelmann H, Grzymisławski M, Pawłowski W, Majewska K, Ryzko-Skiba M, Lachowicz A, Bochenek A, Orzeszko M: Nutritional status of patients in hospitals in Poland. More thorough assessment of nutritional status of adult patients. Pol Merkur Lekarski 2003, 15:151-154.
Jodkowska M, Woynarowska B, Oblacińska A: Test przesiewowy do wykrywania zaburzeń w rozwoju fizycznym u dzieci i młodzieży w wieku szkolnym. Instytut Matki i Dziecka. Warsaw, 2007.
Perek D: Ocena niedoborów w stanie odżywienia dzieci z chorobą nowotworową i metody ich wyrównywania. Habilitation thesis. Warsaw Medical University, Warsaw 1990.
Zalewska-Szewczyk B, Matusiak I, Wyka K, Trelińska J, Stolarska M, Młynarski W: Zmiany w profilu lipidowym u dzieci z ostrą białaczką limfoblastyczną - wpływ choroby i jej leczenia. Med Wieku Rozw 2008, 12:1035- 1040.
Navarese EP, Buffon A, Andreotti F, Kozinski M, Welton N, Fabiszak T, Caputo S, Grzesk G, Kubica A, Swiatkiewicz I, Sukiennik A, Kelm M, De Servi S, Kubica J: Meta-analysis of impact of different types and doses of statins on new-onset diabetes mellitus. Am J Cardiol 2013, 111:1123-1130.
Tan SY, Poh BK, Nadrah MH, Jannah NA, Rahman J, Ismail MN: Nutritional status and dietary intake of children with acute leukaemia during induction or consolidation chemotherapy. J Hum Nutr Diet 2013, 26 Suppl 1:23-33.
Esbenshade AJ, Simmons JH, Koyama T, Lindell RB, Friedman DL: Obesity and insulin resistance in pediatric acute lymphoblastic leukemia worsens during maintenance therapy. Pediatr Blood Cancer 2013, 60:1287-1291.
Al-Tawil MM, Shoeeb AS, Abbas A, El-Tawil A, El- Sayed MH: Lipid Profile and Hepatic Steatosis in Hepatitis C Infected Egyptian Survivors of Childhood Cancer. Pediatr Hematol Oncol. 2013, [Epub ahead of print, doi:10.3109/08880018.2013.825355].
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