Dynamics of C-reactive protein in conditions of substance P block

O. M. Shevchenko, V. O. Sych

DOI: http://dx.doi.org/10.12775/JEHS.2020.10.10.023

Abstract


With the aim to determine the features of the concentration of C-reactive protein in the blood in carrageenan secondary chronic inflammation on the background of blockade of substance P an experimental prospective controlled randomized study was performed on 132 WAG rats in series of 6 rats each in the natural course and using a pharmacological aprepitant praparation – inhibitor of NK-1R in the control and simulated inflammation series for 6 hours, as well as 1, 2, 3, 5, 7, 10, 14, 21, 28 days. the peculiarities of the concentration of C-reactive protein in the blood in carrageenan secondary chronic inflammation on the background of blockade of substance P have been developed.


Keywords


C-reactive protein; secondary chronic inflammation; substance P

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References


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