Polycystic ovary syndrome (PCOS) - risk factor, diagnostic and current treatment

Justyna Wojcik, Aleksandra Obuchowska, Alicja Ozga, Arkadiusz Standyło, Karolina Obuchowska, Paulina Piotrowska

DOI: http://dx.doi.org/10.12775/JEHS.2020.10.09.067



Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders in women in reproductive age, defined as a combination of signs and symptoms resulting from androgen excess and ovarian dysfunction in the absence of other specific diagnoses. PCOS is often associated with an increased risk of obesity, insulin resistance, metabolic disorders and cardiovascular events.


The aim of the study: 

The purpose of this systemic review was to collect and analyze materials about risk factors, diagnostics, and the current treatment of polycystic ovary syndrome.

Material and method

Review of the literature published in 2004-2018.

Description of the state of knowledge:

 PCOS is characterized by an excessive secretion of androgens from the ovaries and / or adrenal glands. Intrinsic ovarian factors, such as altered steroidogenesis, and factors external to the ovary, such as hyperinsulinemia, contribute to the ovarian overproduction of androgens. PCOS requires careful selection of an appropriate diagnostic method and therapeutic approach to combat hyperandrogenism, a consequence of ovarian dysfunction and related metabolic disorders. Treatment of both women at risk of PCOS and those with a confirmed diagnosis of PCOS includes education, healthy lifestyle interventions and symptomatic therapeutic interventions.


PCOS is a complex disorder involving many organs and affecting many body functions. It is important to diagnose this disease as soon as possible in order to implement appropriately selected therapeutic treatment aimed at eliminating disease symptoms and reducing the systemic consequences of hyperandrogenism in patients.


polycystic ovary syndrome; PCOS; diagnostics of PCOS; personalized therapy

Full Text:



Szydlarska D, Grzesiuk W, Bar-Andziak E, Controversies around pathogenesis polycystic ovary syndrome, 2010, 6(3): 141-146

Crespo, Raiane P, Bachega, Tania ASS, Mendonça, Berenice B, Gomes, Larissa G, An update of genetic basis of PCOS pathogenesis. Archives of Endocrinology and Metabolism 2018, 62(3):352-361.

Patel S, Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy, The Journal of Steroid Biochemistry and Molecular Biology, 2018, 182: 27-36

Barber T, Golding S, Alvey C, Global adiposity rather than abnormal regional fat distribution characterizes women with polycystic ovary syndrome, J. Clin. Endocrinol. Metab. 2008; 93: 999–1004.

Meyer C, McGrath B, Teede H, Overweight women with polycystic ovary syndrome have evidence of subclinical cardiovascular disease, J. Clin. Endocrinol. Metab. 2005; 90: 5711– 5716.

Yang O, Kim HL, Weon JI, Seo YR, Endocrine-disrupting chemicals: review of toxicological mechanisms using molecular pathway analysis, J. Cancer Prev., 2015, 20: 12-24

Madnani , Khan K, Chauhan P, Parmar G, Polycystic Ovarian Syndrome, Indian J. Dermatol. Venereol. Leprol., 2013, 79: 310 – 321

Sirmans SM, Pate KA, Epidemiology, diagnosis and treatment of polycystic ovarian syndrome, Clin. Epidemiol., 2013, 6: 1 – 13

Teede H, Deeks A, Moran L, Diamanti-Kandarakis, Kouli C, Bergiele A, Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic symptoms that impacts health throughout life, BMC Med., 2010, 8: 41

Blay SL, Aguiar JVA, Passos IC, Polycystic ovary syndrome and mental disorders: a systematic review and exploratory meta-analysis, Neuropsychiatr. Dis. Treat., 2016, 12: 2895-2903

T.R.E.-S.P.C.W.G.PCOS Consensus Workshop Group, Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome, Fertil. Steril., 2004, 8: 19-25

Piparva KG, Buch JG, Deep vein thrombosis in a woman using combined oral contraceptive pills,J.Pharmacol. Pharmacother. 2011, 2: 185 – 18

Naderpoor N, Shorakae S, Courten B, Misso ML, Moran LJ, Teede HJ, Metformin and lifestyle modification in polycystic ovary syndrome: a systematic review and meta-analysis,Szum. Reprod. Aktualizacja, 2015 , 21: 560 – 574

Davidson R, Motan T, Korownyk C, Clomiphene for anovulatory infertility, Mogą. Fam. Fiz., 2016, 62: 492

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014


POL-index 2011 - 2014


BASE 2011 - 2014




Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska, EuroPub database, NLM Catalog Result - NCBI, BASE, Russian Sciences Index, Arianta.



US NLM = 101679844

101679844 - NLM Catalog Result - NCBI


Find a library that holds this journal: http://worldcat.org/issn/23918306


PBN Poland






Redaction, Publisher and Editorial Office

Publisher and Editorial Office
Department of Physical Culture,
Faculty of Earth Sciences and Spatial Management,
Nicolaus Copernicus University in Toruń, Poland
Address: Str. Lwowska 1, 87-100 Toruń, Poland

  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

Indexed in Index Copernicus Journals Master List.


ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

RG Journal Impact: 0.18 *

*This value is calculated using ResearchGate data and is based on average citation counts from work published in this journal. The data used in the calculation may not be exhaustive.

RG Journal impact history

2020Available summer 2021
2018 / 20190.18

RG Journal impact over time

RG Journal impact

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski


Partnerzy platformy czasopism