The relationship between the diet, microelements, macronutrients and vitamins on the schizophrenia – literature analysis

Magdalena Kozyra, Jakub Klas, Marta Szabat, Anna Maria Samoń-Drzewicka, Joanna Milanowska

DOI: http://dx.doi.org/10.12775/JEHS.2020.10.09.043

Abstract


Introduction: Schizophrenia is a disease that affects approximately 1% of the population. It begins in adult humans. It turns out that there are factors that predispose to schizophrenia, and by modifying your lifestyle, you can reduce the likelihood of its occurrence. One of such factors is the diet and microelements, macronutrients and vitamins that we consume every day.

The aim of the study: The aim of this study was to find out the relationship between the diet, microelements, macronutrients, vitamins and the schizophrenia disease.

Material and method: The research of articles was done in the websites such as PubMed and Google Scholar.

Description of the state of knowledge: Ketogenic and gluten-free diet are promising tools in decreasing the symptoms of and treating schizophrenia. Micro- and macroelement imbalances are present in schizophrenic patients, but their correlation with development of schizophrenia is not clear. Folate, vitamin D and vitamin B12 supplementation could prove useful in the treatment.

Summary: There are many studies that try to combine the implications of a balanced diet and the proper supply of elements and their impact on schizophrenia's occurence and symptomology. Still, futher investigation of these topics is needed to provide the most suitable guidelines and applications of proper nutrition of schizophrenic patients.


Keywords


schizophrenia; diet; microelements; macronutrients; vitamins

Full Text:

PDF

References


Whiteford HA, Degenhardt L, Rehm J, Baxter AJ, Ferrari AJ, Erskine HE, Charlson FJ, Norman RE, Flaxman AD, Johns N, et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 2013;382:1575–1586. doi: 10.1016/S0140-6736(13)61611-6.

[1] Janoutová J, Janácková P, Serý O, Zeman T, Ambroz P, Kovalová M, Varechová K, Hosák L, Jirík V, Janout V. Epidemiology and risk factors of schizophrenia. Neuro Endocrinol Lett. 2016;37(1):1-8.

Palijan TŽ, Kovačević D, Vlastelica M, Dadić-Hero E, Sarilar M. Quality of Life of Persons Suffering from Schizophrenia, Psoriasis and Physical Disabilities. Psychiatr Danub. 2017 Mar;29(1):60-65

Hofer A, Mizuno Y, Wartelsteiner F, Wolfgang Fleischhacker W, Frajo-Apor B, Kemmler G, Mimura M, Pardeller S, Sondermann C, Suzuki T, Welte A, Uchida H. Quality of life in schizophrenia and bipolar disorder: The impact of symptomatic remission and resilience. Eur Psychiatry. 2017 Oct;46:42-47

Mueser K.T., McGurk S.R., Schizophrenia. The Lancet, 363 (9426), London, England 2004, s. 2063–2072, DOI: 10.1016/S0140-6736(04)16458-1, PMID: 15207959.

Janssen I. et al. Childhood abuse as a risk factor for psychotic experiences, „Acta Psychiatrica Scandinavica”, 109 (1), 2004, s. 38–45, PMID: 14674957.

Suvisaari J, Keinänen J, Eskelinen S, Mantere O. Diabetes and Schizophrenia. Curr Diab Rep. 2016 Feb;16(2):16

Phensy A, Driskill C, Lindquist K, Guo L, Jeevakumar V, Fowler B, et al. Antioxidant Treatment in Male Mice Prevents Mitochondrial and Synaptic Changes in an NMDA Receptor Dysfunction Model of Schizophrenia. eneuro. 2017;4. doi:10.1523/eneuro.0081-17.2017.

Mccreadie, R. G., Kelly, C., Connolly, M., Williams, S., Baxter, G., Lean, M., & Paterson, J. R. (2005). Dietary improvement in people with schizophrenia. British Journal of Psychiatry, 187(4), 346-351. doi:10.1192/bjp.187.4.346

Joukamaa, M., Heliovaara, M., Knekt, P. et al (2001) Mental disorders and cause specific mortality. British Journal of Psychiatry, 179, 498–502

McCreadie, R. G., MacDonald, E., Blacklock, C. et al (1998) Dietary intake of schizophrenia patients in Nithsdale, Scotland: Case Control Study. BMJ; 317, 784–785

McCreadie, R. G. (2003) Diet, smoking and cardiovascular risk in people with schizophrenia. Descriptive study. British Journal of Psychiatry, 183, 534–539

Zimmerman, U., Kraus, T., Himmerich, H. et al (2003) Epidemiology, implications and mechanisms underlying drug-induced weight gain in psychiatric patients. Journal of Psychiatric Research, 37, 193–220

Fontaine, K. R., Moonseong, H., Harrigan, E. P. et al (2001) Estimating the consequences of antipsychotic induced weight gain on health and mortality rate. Psychiatric Research, 101, 277–288

Włodarczyk, A., Wiglusz, M. S., & Cubała, W. J. (2018). Ketogenic diet for schizophrenia: Nutritional approach to antipsychotic treatment [Abstract]. Medical Hypotheses, 118, 74-77. doi:10.1016/j.mehy.2018.06.022

Gilbert-Jaramillo, J., Vargas-Pico, D., Espinosa-Mendoza, T., Falk, S., Llanos-Fernandez, K., Guerrero-Haro, J., . . . Palmer, C. (2018). The effects of the ketogenic diet on psychiatric symptomatology, weight and metabolic dysfunction in schizophrenia patients. Clinical Nutrition and Metabolism, 1(1). doi:10.15761/cnm.1000105

Ketogenic diet for schizophrenia: Clinical implication. (n.d.). Retrieved September 13, 2020, from https://www.ncbi.nlm.nih.gov/pubmed/31192814

Levinta, A., Mukovozov, I., & Tsoutsoulas, C. (2018). Use of a Gluten-Free Diet in Schizophrenia: A Systematic Review. Advances in Nutrition, 9(6), 824-832. doi:10.1093/advances/nmy056

Singh M, Kay SR. Wheat gluten as a pathogenic factor in schizophrenia. Science 1976;191(4225):401–2

Reichelt KL, Sagedal E, Landmark J, Sangvik BT, Eggen O, Scott H. The effect of gluten-free diet on urinary peptide excretion and clinical state in schizophrenia. J Orthomol Med 1990;5(4):223–39.

Jackson J, Eaton W, Cascella N, Fasano A, Warfel D, Feldman S, Richardson C, Vyas G, Linthicum J, Santora D et al. A gluten-free diet in people with schizophrenia and anti-tissue transglutaminase or anti-gliadin antibodies. Schizophr Res 2012;140(1–3):262–3

McCreadie, R., Kelly, C., Connolly, M., Williams, S., Baxter, G., Lean, M., & Paterson, J. (2018, January 02). Dietary improvement in people with schizophrenia: The British Journal of Psychiatry. Retrieved September 13, 2020, from https://doi.org/10.1192/bjp.187.4.346

Lin T, Liu T, Lin Y, Yan L, Chen Z, Wang J. Comparative study on serum levels of macro and trace elements in schizophrenia based on supervised learning methods. J Trace Elem Med Biol. 2017;43:202-208. doi:10.1016/j.jtemb.2017.03.010

Ma J, Yan L, Guo T, et al. Association between Serum Essential Metal Elements and the Risk of Schizophrenia in China. Sci Rep. 2020;10(1):10875. Published 2020 Jul 3. doi:10.1038/s41598-020-66496-7

Liu T, Lu QB, Yan L, et al. Comparative Study on Serum Levels of 10 Trace Elements in Schizophrenia. PLoS One. 2015;10(7):e0133622. Published 2015 Jul 17. doi:10.1371/journal.pone.0133622

Joe P, Petrilli M, Malaspina D, Weissman J. Zinc in schizophrenia: A meta-analysis. Gen Hosp Psychiatry. 2018;53:19-24. doi:10.1016/j.genhosppsych.2018.04.004

Cao B, Yan L, Ma J, et al. Comparison of serum essential trace metals between patients with schizophrenia and healthy controls. J Trace Elem Med Biol. 2019;51:79-85. doi:10.1016/j.jtemb.2018.10.009

Li Z, Liu Y, Li X, et al. Association of Elements with Schizophrenia and Intervention of Selenium Supplements. Biol Trace Elem Res. 2018;183(1):16-21. doi:10.1007/s12011-017-1105-0

Goff DC, Bottiglieri T, Arning E, et al. Folate, homocysteine, and negative symptoms in schizophrenia. Am J Psychiatry. 2004;161(9):1705-1708. doi:10.1176/appi.ajp.161.9.1705

Herrán A, García-Unzueta MT, Amado JA, López-Cordovilla JJ, Díez-Manrique JF, Vázquez-Barquero JL. Folate levels in psychiatric outpatients. Psychiatry Clin Neurosci. 1999;53(4):531-533. doi:10.1046/j.1440-1819.1999.00572.x

McGrath JJ, Eyles DW, Pedersen CB, et al. Neonatal Vitamin D Status and Risk of Schizophrenia: A Population-Based Case-Control Study. Arch Gen Psychiatry. 2010;67(9):889–894. doi:10.1001/archgenpsychiatry.2010.110

Itzhaky D, Amital D, Gorden K, Bogomolni A, Arnson Y, Amital H. Low serum vitamin D concentrations in patients with schizophrenia. Isr Med Assoc J. 2012;14(2):88-92.

Zhang Y, Hodgson NW, Trivedi MS, et al. Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia. PLoS One. 2016;11(1):e0146797. Published 2016 Jan 22. doi:10.1371/journal.pone.0146797

Kemperman RF, Veurink M, van der Wal T, et al. Low essential fatty acid and B-vitamin status in a subgroup of patients with schizophrenia and its response to dietary supplementation. Prostaglandins Leukot Essent Fatty Acids. 2006;74(2):75-85. doi:10.1016/j.plefa.2005.11.004


Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM




Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska, EuroPub database, NLM Catalog Result - NCBI, BASE, Russian Sciences Index, Arianta.

https://zdb-katalog.de/title.xhtml?idn=1080187162

https://europub.co.uk/journals/22625

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Publisher and Editorial Office
Department of Physical Culture,
Faculty of Earth Sciences and Spatial Management,
Nicolaus Copernicus University in Toruń, Poland
Address: Str. Lwowska 1, 87-100 Toruń, Poland

  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

RG Journal Impact: 0.18 *

*This value is calculated using ResearchGate data and is based on average citation counts from work published in this journal. The data used in the calculation may not be exhaustive.

RG Journal impact history

2020Available summer 2021
2018 / 20190.18
20170.07
20160.03

RG Journal impact over time

RG Journal impact
0.180.160.140.120.100.080.060.040.02201620172018
  

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)

Partnerzy platformy czasopism