Clinical and morphological features of combined hyperplastic diseases of the uterus against the background of adenomyosis

N. M. Rozhkovskaya, V. O. Sitnikova, S. M. Sivyi, I. S. Lomakina



To determine clinical and morphological features of combined uterine hyperplastic diseases in premenopausal women at the background of adenomyosis, 62 patients operated on for chronic abnormal uterine bleeding were examined. The control group consisted of 30 premenopausal patients who applied for preventive examination. Anthropometric and ultrasound examinations, assessment of carbohydrate and lipid metabolism, histologic examination were done. It has been established that uterine hyperplasia patients often had lipid metabolism damages (dislipidemy) and damages of carbohydrate one (alimentary – constitutional obesity, metabolic syndrome) which worsen the clinical course of the main disease. According to histological examination data, the activity of adenomyosis foci in patients with comorbid uterine pathology correlated with the severity of clinical manifestations (abnormal uterine bleeding, pain) and the presence of comorbid lesions (concomitant endometrial hyperplasia, chronic endometriosis, fibroids, endometriosis).


hyperplastic diseases of the uterus; adenomyosis; endometriosis; dislipidemy; metabolic syndrome

Full Text:



Nozari N. Screening and management of Metabolic Syndrome // Shiraz E-Medical Journal. 2011. Vol. 12. № 3. P. 144–149.

Sidorenko AV Morphological features of adenomyosis in women of reproductive age who have combined pathology of the uterus / AV Sidorenko.// Odessa Medical Journal. - 2018. - №2. - P. 44 - 49.

Goncharenko G. Yu. Clinical and morphological analysis of genital endometriosis./ G. Yu. Goncharenko.// Achievements of biology and medicine. - 2016.– №1 (27). - P. 57 - 60.

Kunz G. Adenomyosis as a disorder of the early and late human reproductive period / G. Kunz, M. Herbertz, D. Beil // Reprod. Biomed. Online. - 2017. - Vol. 15. ¹6.-P. 681-685

Hamdan M. Influence of endometriosis on assisted reproductive technology outcomes: a systematic review and meta-analysis / M. Hamdan, S.Z. Omar, G. Dunselman // Obstet. Gynecol. - 2015. - Vol. 125. ¹ l.-P. 79-88.

Healy D.L., Breheny S., Halliday J. et al. Prevalence and risk factors for obstetric haemorrhage in 6730 singleton births after assisted reproductive technology in Victoria Australia / D.L. Healy, S. Breheny, J. Halliday // Hum. Reprod.-2013.-Vol. 25. -¹ l.-P. 265- 274.

Unified clinical protocol of primary, secondary (specialized) and tertiary (highly specialized) medical care. Tactics of management of patients with genital endometriosis. Approved by the Order of the Ministry of Health from 06.04.2016, №319 // Obstetrics. Gynecology. Genetics.-2016.-Vol.2, №2.-P.61-74.

Damirov MM, Shabanov AM A new look at the pathogenesis of adenomyosis / MM Damirov.// Journal of NV Sklifosovsky Urgent medical care. - 2013. - №. 3.– P. 23 - 27

Kornatska AG Peculiarities of anatomical and functional state of pelvic organs and generative function in women with uterine leiomyoma / Kornatska AG, Kolesnichenko IS, Flaxemberg MA, Revenko OO // Women's health. - K., 2014. - № 10 (96). - P. 134–136

Yarotsky ME, Demyanenko LV, Doroga OP Peculiarities of benign uterine diseases in women of reproductive age with metabolic syndrome // Clinical Endocrinol and endocrine surgery.- 2016.- N 3.- C. 65-75

Anfinogenova Ye. A. Active and inactive adenomiosis: comparative analysis in foci of ectopic endometrium (expression of aromatize p-450, receptors of estrogenes alfa and beta, receptors of progesterone) // Herald of education and development of Russian academy of natural sciences.- 20116.- N 20.- P. 74 -82

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

POL-index 2011 - 2014

BASE 2011 - 2014

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska, EuroPub database, NLM Catalog Result - NCBI, BASE, Russian Sciences Index, Arianta.

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

Find a library that holds this journal:


PBN Poland



Redaction, Publisher and Editorial Office

Publisher and Editorial Office
Department of Physical Culture,
Faculty of Earth Sciences and Spatial Management,
Nicolaus Copernicus University in Toruń, Poland
Address: Str. Lwowska 1, 87-100 Toruń, Poland

  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at

Indexed in Index Copernicus Journals Master List.,p24782242,3.html

ICV 2019 = 100.00 ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

RG Journal Impact: 0.18 *

*This value is calculated using ResearchGate data and is based on average citation counts from work published in this journal. The data used in the calculation may not be exhaustive.

RG Journal impact history

2020Available summer 2021
2018 / 20190.18

RG Journal impact over time

RG Journal impact

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ)

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski


Partnerzy platformy czasopism