TY - JOUR AU - Pastushyna, Anna I. PY - 2016/09/28 Y2 - 2024/03/29 TI - Peculiarities of platelet hemostasis changes in patients with arterial hypertension and coronary artery disease, depending on the presence of microalbuminuria JF - Journal of Education, Health and Sport JA - J Educ Health Sport VL - 6 IS - 9 SE - Research Articles DO - UR - https://apcz.umk.pl/JEHS/article/view/3887 SP - 610-615 AB - <p class="A"><strong>Pastushyna Anna I.</strong><strong> </strong><strong>Peculiarities of platelet hemostasis changes in patients with arterial hypertension and coronary artery disease, depending on the presence of microalbuminuria. </strong><strong>Journal of Education, Health and </strong><strong>Sport. 2016;6(9):6</strong><strong>10</strong><strong>-6</strong><strong>15</strong><strong>. eISSN 2391-8306. DOI </strong><strong><span style="text-decoration: underline;"><a href="http://dx.doi.org/10.5281/zenodo.158164">http://dx.doi.org/10.5281/zenodo.158164</a></span></strong><strong></strong></p><p><strong><span style="text-decoration: underline;"><a href="/index.php/johs/article/view/3887">http://ojs.ukw.edu.pl/index.php/johs/article/view/3887</a></span></strong><strong></strong></p><p><strong> </strong></p><p><strong> </strong></p><p><strong> </strong></p><p><strong> </strong></p><p align="center"><strong>The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).</strong><strong></strong></p><p align="center"><strong>755 Journal of Education, Health and Sport eISSN 2391-8306 7</strong><strong></strong></p><p align="center"><strong>© The Author (s) 2016;</strong><strong></strong></p><p align="center"><strong>This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland</strong><strong></strong></p><p align="center"><strong>Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,</strong><strong></strong></p><p align="center"><strong>provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License</strong><strong></strong></p><p align="center"><strong>(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.</strong><strong></strong></p><p align="center"><strong>This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial</strong><strong></strong></p><p align="center"><strong>use, distribution and reproduction in any medium, provided the work is properly cited.</strong><strong></strong></p><p align="center"><strong>The authors declare that there is no conflict of interests regarding the publication of this paper.</strong><strong></strong></p><p align="center"><strong>Received: 02.09.2016. Revised 24.09.2016. Accepted: 24</strong><strong>.09.2016.</strong><strong></strong></p><p align="center"><strong> </strong></p><p align="center"><strong> </strong></p><p align="center"><strong> </strong></p><p class="A" align="center"><strong>Peculiarities of platelet hemostasis changes in patients with arterial hypertension and coronary artery disease, depending on the presence of microalbuminuria</strong><strong></strong></p><p class="A" align="center"><strong> </strong></p><p class="A" align="center"><strong>Anna I. Pastushyna</strong><strong></strong></p><p class="A" align="center"><strong> </strong></p><p class="A" align="center"><strong>Bogomolets national medical university,</strong></p><p class="A" align="center"><strong>Department of propedeutics of internal medicine N1 </strong><strong></strong></p><p class="A"><strong>Abstract</strong><strong></strong></p><p>The activity of platelets and microalbuminuria can be considered as a reflection of endothelial function both in arterial hypertension and in other cardiovascular diseases. To assess the platelet hemostasis we examined 98 people: 14 apparently healthy (Group 1, control), 34 patients with arterial hypertension, the 2-nd stage, in combination with coronary artery disease with concomitant MAU (group 2), 50 patients with arterial hypertension, the 2-nd stage, in combination with coronary artery disease without concomitant MAU (3 Group). Analysis of induced platelet aggregation revealed decrease in ADP and AA-induced aggregation in the study groups of patients, which may be due to the treatment of this category of patients with acetylsalicylic acid, which has a direct effect on the AA-stimulated aggregation. Decrease of expression of ADP aggregation in patients of surveyed groups may be due to a receiving clopidogrel by patients. It is noteworthy that despite treatment with antiplatelet drugs, collagen and epinephrine-induced aggregation were not significantly different from the control group.</p><p> </p><p class="A"><strong>Key words</strong><strong>: arterial hypertension, coronary artery disease, microalbuminuria, hemostasis, platelets aggregation. </strong><strong></strong></p> ER -