@article{Glazunov_Glazunova_Moroz_2015, title={Влияние токсиканта делагила на морфологические изменения в слизистой оболочке полости рта крыс при разном уровне поступления алиментарных полифенолов = The influence of the toxicant delagil on the morphological changes in the oral mucosa of rats in the different levels of receipts of alimentary polyphenols}, volume={5}, url={https://apcz.umk.pl/JEHS/article/view/3162}, abstractNote={<p><strong>Glazunov</strong><strong> </strong><strong>O</strong><strong>. </strong><strong>A</strong><strong>., </strong><strong>Glazunova</strong><strong> </strong><strong>S</strong><strong>. </strong><strong>A</strong><strong>., </strong><strong>Moroz</strong><strong> </strong><strong>V</strong><strong>. </strong><strong>E</strong><strong>. Влияние токсиканта делагила на морфологические изменения в слизистой оболочке полости рта крыс при разном уровне поступления алиментарных полифенолов = </strong><strong>The</strong><strong> </strong><strong>influence</strong><strong> </strong><strong>of</strong><strong> </strong><strong>the</strong><strong> </strong><strong>toxicant</strong><strong> </strong><strong>delagil</strong><strong> </strong><strong>on</strong><strong> </strong><strong>the</strong><strong> </strong><strong>morphological</strong><strong> </strong><strong>changes</strong><strong> </strong><strong>in</strong><strong> </strong><strong>the</strong><strong> </strong><strong>oral</strong><strong> </strong><strong>mucosa</strong><strong> </strong><strong>of</strong><strong> </strong><strong>rats</strong><strong> </strong><strong>in</strong><strong> </strong><strong>the</strong><strong> </strong><strong>different</strong><strong> </strong><strong>levels</strong><strong> </strong><strong>of</strong><strong> </strong><strong>receipts</strong><strong> </strong><strong>of</strong><strong> </strong><strong>alimentary</strong><strong> </strong><strong>polyphenols. </strong><strong>Journal of Education, Health and Sport</strong><strong>. </strong><strong>2015;5(12):326-332</strong><strong>. </strong><strong>ISSN 2391-8306</strong><strong>. DOI</strong><strong></strong><strong><span style="text-decoration: underline;"><a href="http://dx.doi.org/10.5281/zenodo.35466">http://dx.doi.org/10.5281/zenodo.35466</a></span></strong></p><p><strong><span style="text-decoration: underline;"><a href="/index.php/johs/article/view/2015%3B5%2812%29%3A326-332%0d">http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2812%29%3A326-332</a></span></strong></p><p><strong><span style="text-decoration: underline;"><a href="http://pbn.nauka.gov.pl/works/682259%0d">http://pbn.nauka.gov.pl/works/682259</a></span></strong></p><p><strong>Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014</strong><a href="http://journal.rsw.edu.pl/index.php/JHS/issue/archive"><strong>http://journal.rsw.edu.pl/index.php/JHS/issue/archive</strong></a></p><p> </p><p align="center"><strong>Deklaracja.</strong></p><p align="center"><strong>Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.</strong></p><p align="center"><strong>Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.</strong></p><p align="center"><strong>The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).</strong></p><p align="center"><strong>© The Author (s) 2015;</strong></p><p align="center"><strong>This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland</strong></p><p align="center"><strong>Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,</strong></p><p align="center"><strong>provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License</strong></p><p align="center"><strong>(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.</strong></p><p align="center"><strong>This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial</strong></p><p align="center"><strong>use, distribution and reproduction in any medium, provided the work is properly cited.</strong></p><p align="center"><strong>The authors declare that there is no conflict of interests regarding the publication of this paper.</strong></p><p align="center"><strong>Received: 10.11.2015. Revised 15.12.2015. Accepted: 17.12.2015.</strong></p><p align="center"><strong> </strong></p><p><strong>УДК</strong><strong>: (579.23 – 036.632+615.372): 616.311:599.323.4</strong></p><p><strong>UDC: (579.23 – 036.632+615.372): 616.311:599.323.4</strong></p><p><strong> </strong></p><p><strong> </strong></p><p align="center"><strong>Влияние токсиканта делагила на морфологические изменения в слизистой оболочке полости рта крыс при разном уровне поступления алиментарных полифенолов</strong></p><p align="center"><strong> </strong></p><p align="center"><strong>THE INFLUENCE OF THE TOXICANT DELAGIL ON THE MORPHOLOGICAL CHANGES IN THE ORAL MUCOSA OF RATS IN THE DIFFERENT LEVELS OF RECEIPTS OF ALIMENTARY POLYPHENOLS</strong></p><p><strong> </strong></p><p align="center"><strong>Глазунов О. А., Глазунова С. А., Мороз В. Е.</strong></p><p align="center"><strong>Glazunov O. A., Glazunova S. A., Moroz V. E.</strong></p><p><strong> </strong></p><p align="center"><strong>Днепропетровская медицинская академия МОЗ Украины,</strong></p><p align="center"><strong>Стоматологическая поликлиника № 1 г. Кривой Рог</strong></p><p align="center"><strong>Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine,</strong></p><p align="center"><strong>Stomatologic polyclinic number</strong><strong> 1 of the</strong><strong> Krivoy Rog</strong><strong></strong></p><p><strong> </strong></p><p align="center"><strong>Реферат</strong></p><p>В опытах на 22 белых крысах линии Вистар изучено влияние токсиканта делагила на морфологические изменения слизистой оболочки полости рта крыс в условиях нормального поступления и лишения животных растительной пищи. Введение на фоне полноценного рациона вивария вызвало на поверхности эпителиального пласта появление гигантских эпителиоцитов и отека в межклеточных пространствах. Хроническое лишение крыс алиментарных растительных полифенолов усиливало чувствительность слизистой оболочки полости рта к действию делагила и вызывало более значительные изменения в эпителиальном пласте и в соединительной ткани собственной пластинки слизистой оболочки щеки крыс.</p><p><strong> </strong></p><p><strong>Ключевые слова:</strong> делагил, алиментарная недостаточность полифенолов, эпителиальный пласт, гигантские эпителиоциты, митотические процессы, соединительная ткань собственной пластинки, деструктивно-воспалительные изменения, белые крысы.</p><p> </p><p> </p><p> </p><p align="center"><strong>Summary</strong></p><p><strong>The Aim</strong><strong> </strong>of  study was to investigate the the influence of delagila on the morphological changes in the connective tissue of the lamina propria and the epithelium of the buccal mucosa of rats under conditions of normal receipts and deprivation of the animals plant foods.</p><p><strong>Materials and methods.</strong> In the experiment were taken 22 white rats, distributed in the following groups. 1st group (7 rats) - intact; 2nd group (7) was obtained delagil per os at a dose of 5 mg / kg body weight of rats 5 times a week, against full vivarium ration. Rats of group 3 (8) was prepared delagil with the content on their diet, devoid of plant food. Time of the experiment was 60 days.</p><p><strong>Results and conclusions. </strong>The introduction on the background of a full ration of vivarium caused on the surface of the epithelial layer appearance of a gigant epithelial cells and swelling in the intercellular spaces. Chronic nutritional deprivation ratsof the plant polyphenols increased the sensitivity of the oral mucosa to the action delagila and caused a significant change in the epithelial layer of connective tissue in the lamina propria of the buccal mucosa of rats.</p><p><strong> </strong></p><p><strong>Key words: </strong>delagil, nutritional deficiency of polyphenols, epithelial layer, giant epithelial cells, mitotic process, the connective tissue of the lamina propria, destructive and inflammatory changes, white rats.</p>}, number={12}, journal={Journal of Education, Health and Sport}, author={Glazunov, Oleh Anatolievich and Glazunova, Svetlana Aleksandrovna and Moroz, Victoria Evgenievna}, year={2015}, month={Dec.}, pages={326–332} }